William T Golde

Summary

Affiliation: Agricultural Research Service
Country: USA

Publications

  1. ncbi A rapid, simple, and humane method for submandibular bleeding of mice using a lancet
    William T Golde
    Plum Island Animal Disease Center ARS, US Department of Agriculture, Greenport, NY 11944, USA
    Lab Anim (NY) 34:39-43. 2005
  2. pmc IgA antibody response of swine to foot-and-mouth disease virus infection and vaccination
    Juan M Pacheco
    Plum Island Animal Disease Center, Agricultural Research Service, USDA, Greenport, NY 11944 0848, USA
    Clin Vaccine Immunol 17:550-8. 2010
  3. pmc Constitutive expression of alpha interferon by skin dendritic cells confers resistance to infection by foot-and-mouth disease virus
    Elida M Bautista
    PIADC, ARS, USDA, P O Box 848, Greenport, NY 11944 0848, USA
    J Virol 79:4838-47. 2005
  4. ncbi Vaccination against foot-and-mouth disease virus confers complete clinical protection in 7 days and partial protection in 4 days: Use in emergency outbreak response
    William T Golde
    Plum Island Animal Disease Center, Foot and Mouth Disease Unit PIADC, ARS, USDA P O Box 848 Greenport, NY 11944, USA
    Vaccine 23:5775-82. 2005
  5. doi Loss of plasmacytoid dendritic cell function coincides with lymphopenia and viremia during foot-and-mouth disease virus infection
    Charles K Nfon
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944 0848, USA
    Viral Immunol 23:29-41. 2010
  6. doi Activation of porcine natural killer cells and lysis of foot-and-mouth disease virus infected cells
    Felix N Toka
    Plum Island Animal Disease Center, Agricultural Research Service, US Department of Agriculture, Greenport, New York 11944, USA
    J Interferon Cytokine Res 29:179-92. 2009
  7. doi Immune evasion during foot-and-mouth disease virus infection of swine
    William T Golde
    Plum Island Animal Disease Center, ARS, USDA, Greenport, NY 11944 0848, USA
    Immunol Rev 225:85-95. 2008
  8. ncbi Immunopotentiation of a foot-and-mouth disease virus subunit vaccine by interferon alpha
    Sonia de Avila Botton
    Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, U S Department of Agriculture, P O Box 848, Greenport, NY 11944, United States
    Vaccine 24:3446-56. 2006
  9. pmc Natural killer cell dysfunction during acute infection with foot-and-mouth disease virus
    Felix N Toka
    Plum Island Animal Disease Center, Agricultural Research Service, USDA, Greenport, New York 11944, USA
    Clin Vaccine Immunol 16:1738-49. 2009
  10. ncbi Induction of lymphopenia and inhibition of T cell function during acute infection of swine with foot and mouth disease virus (FMDV)
    Elida M Bautista
    Plum Island Animal Diseases Center, Agricultural Research Service, USDA, P O Box 848, Greenport, NY 11944, USA
    Vet Immunol Immunopathol 92:61-73. 2003

Collaborators

Detail Information

Publications23

  1. ncbi A rapid, simple, and humane method for submandibular bleeding of mice using a lancet
    William T Golde
    Plum Island Animal Disease Center ARS, US Department of Agriculture, Greenport, NY 11944, USA
    Lab Anim (NY) 34:39-43. 2005
    ..The authors describe an inexpensive, disposable, single-use lancet for submandibular bleeding of mice that allows investigators to quickly draw 0.2-0.5 ml of blood without the use of anesthesia...
  2. pmc IgA antibody response of swine to foot-and-mouth disease virus infection and vaccination
    Juan M Pacheco
    Plum Island Animal Disease Center, Agricultural Research Service, USDA, Greenport, NY 11944 0848, USA
    Clin Vaccine Immunol 17:550-8. 2010
    ..Further, the presence of the IgA antivirus in serum correlates with the presence of such antibodies in saliva...
  3. pmc Constitutive expression of alpha interferon by skin dendritic cells confers resistance to infection by foot-and-mouth disease virus
    Elida M Bautista
    PIADC, ARS, USDA, P O Box 848, Greenport, NY 11944 0848, USA
    J Virol 79:4838-47. 2005
    ..This is the first demonstration of the constitutive expression of IFN-alpha in resident, tissue-derived DC and indicates that skin DC can play an important role in the innate immune response of swine to viral infections...
  4. ncbi Vaccination against foot-and-mouth disease virus confers complete clinical protection in 7 days and partial protection in 4 days: Use in emergency outbreak response
    William T Golde
    Plum Island Animal Disease Center, Foot and Mouth Disease Unit PIADC, ARS, USDA P O Box 848 Greenport, NY 11944, USA
    Vaccine 23:5775-82. 2005
    ..These significant effects at 4 days post vaccination, confirmed in two separate trials, support the value of using currently available vaccines as a first line of defense against foot-and-mouth disease (FMD) outbreaks...
  5. doi Loss of plasmacytoid dendritic cell function coincides with lymphopenia and viremia during foot-and-mouth disease virus infection
    Charles K Nfon
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944 0848, USA
    Viral Immunol 23:29-41. 2010
    ..Rapid induction of serum IFN-alpha, albeit short-lived, may contribute to the rapid resolution of FMDV viremia prior to induction of specific immunity...
  6. doi Activation of porcine natural killer cells and lysis of foot-and-mouth disease virus infected cells
    Felix N Toka
    Plum Island Animal Disease Center, Agricultural Research Service, US Department of Agriculture, Greenport, New York 11944, USA
    J Interferon Cytokine Res 29:179-92. 2009
    ..The enhancement of porcine NK cell activity by proinflammatory cytokines offers a promising tool for development of antiviral approaches against virus infection...
  7. doi Immune evasion during foot-and-mouth disease virus infection of swine
    William T Golde
    Plum Island Animal Disease Center, ARS, USDA, Greenport, NY 11944 0848, USA
    Immunol Rev 225:85-95. 2008
    ..Understanding how this virus subverts the innate response will provide valuable information for the development of rapidly acting biotherapeutics to use in response to an outbreak of FMDV...
  8. ncbi Immunopotentiation of a foot-and-mouth disease virus subunit vaccine by interferon alpha
    Sonia de Avila Botton
    Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, U S Department of Agriculture, P O Box 848, Greenport, NY 11944, United States
    Vaccine 24:3446-56. 2006
    ..Thus, pIFN-alpha enhances the long-term level of protection induced by the Ad5-FMD vaccine, supporting its use as a potential adjuvant in FMD vaccination strategies...
  9. pmc Natural killer cell dysfunction during acute infection with foot-and-mouth disease virus
    Felix N Toka
    Plum Island Animal Disease Center, Agricultural Research Service, USDA, Greenport, New York 11944, USA
    Clin Vaccine Immunol 16:1738-49. 2009
    ..These effects likely culminate in brief but effective viral immune evasion, allowing the virus to replicate and disseminate within the host...
  10. ncbi Induction of lymphopenia and inhibition of T cell function during acute infection of swine with foot and mouth disease virus (FMDV)
    Elida M Bautista
    Plum Island Animal Diseases Center, Agricultural Research Service, USDA, P O Box 848, Greenport, NY 11944, USA
    Vet Immunol Immunopathol 92:61-73. 2003
    ..These characteristics of acute phase infection likely play an important role in viral pathogenesis, propagation and shedding of viral particles and may be targeted as a way of improving vaccine formulations...
  11. doi Interferon-alpha production by swine dendritic cells is inhibited during acute infection with foot-and-mouth disease virus
    Charles K Nfon
    Plum Island Animal Disease Center, Agricultural Research Service, U S Department of Agriculture, Greenport, New York 11944 0848, USA
    Viral Immunol 21:68-77. 2008
    ..These data indicate that inhibition of the IFN-alpha response of dendritic cell populations from blood and skin by FMDV enhances viral pathogenesis in infected animals...
  12. pmc Characterization of cytotoxic T lymphocyte function after foot-and-mouth disease virus infection and vaccination
    Jared R Patch
    Plum Island Animal Disease Center, Agricultural Research Service, USDA, Greenport, New York, USA
    Viral Immunol 26:239-49. 2013
    ..These results provide new insights showing induction of CTL responses to FMDV following infection or vaccination, and create the potential for improving vaccine performance by targeting cellular immunity...
  13. ncbi Rapid protection of cattle from direct challenge with foot-and-mouth disease virus (FMDV) by a single inoculation with an adenovirus-vectored FMDV subunit vaccine
    Juan M Pacheco
    Plum Island Animal Disease Center, North Atlantic Area, Agricultural Research Service, U S Department of Agriculture, Greenport, NY 11944, USA
    Virology 337:205-9. 2005
    ..Both control animals developed typical signs of FMD including fever and vesicular lesions on all 4 feet. All 5 vaccinated animals were protected against disseminated disease...
  14. ncbi A synthetic peptide containing the consensus sequence of the G-H loop region of foot-and-mouth disease virus type-O VP1 and a promiscuous T-helper epitope induces peptide-specific antibodies but fails to protect cattle against viral challenge
    Luis L Rodriguez
    Agricultural Research Service, US Department of Agriculture, Plum Island Animal Disease Center, Greenport, NY 11944, USA
    Vaccine 21:3751-6. 2003
    ..We conclude that although the synthetic peptide induced an antibody response in cattle, it failed to confer protection against FMDV challenge...
  15. pmc Induction of foot-and-mouth disease virus-specific cytotoxic T cell killing by vaccination
    Jared R Patch
    Plum Island Animal Disease Center, Agricultural Research Service, USDA, Greenport, New York 11944, USA
    Clin Vaccine Immunol 18:280-8. 2011
    ..Further, we confirm these results by MHC tetramer staining. This work presents the first demonstration of FMDV-specific CTL killing and confirmation by MHC tetramer staining in response to vaccination against FMDV...
  16. doi An alternate delivery system improves vaccine performance against foot-and-mouth disease virus (FMDV)
    Mital Pandya
    Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, NY, United States
    Vaccine 30:3106-11. 2012
    ....
  17. doi Langerhans cells in porcine skin
    Charles K Nfon
    Plum Island Animal Disease Center, ARS, USDA, Greenport, NY 11944, United States
    Vet Immunol Immunopathol 126:236-47. 2008
    ....
  18. pmc Accessory-cell-mediated activation of porcine NK cells by toll-like receptor 7 (TLR7) and TLR8 agonists
    Felix N Toka
    Plum Island Animal Disease Center, ARS, USDA, P O Box 848, Greenport, NY 11944, USA
    Clin Vaccine Immunol 16:866-78. 2009
    ....
  19. doi Rapid and transient activation of γδ T cells to IFN-γ production, NK cell-like killing, and antigen processing during acute virus infection
    Felix N Toka
    Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Greenport, NY 11944, USA
    J Immunol 186:4853-61. 2011
    ..However, these results are unique in that all these functions are detected in the same samples of WC1(+) γδ T cells, suggesting a pivotal role of these cells in controlling virus infection...
  20. ncbi Vesicular stomatitis New Jersey virus (VSNJV) infects keratinocytes and is restricted to lesion sites and local lymph nodes in the bovine, a natural host
    Charles F C Scherer
    Plum Island Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, PO Box 848, Greenport, NY 11944, USA
    Vet Res 38:375-90. 2007
    ..The pathogenesis model shown herein could be useful for in-vivo tracking of virus infection and local immune responses...
  21. ncbi Characterization and functional analysis of skin-derived dendritic cells from swine without a requirement for in vitro propagation
    Elida M Bautista
    Foot and Mouth Disease Unit, Agricultural Research Service, USDA, Plum Island Animal Disease Center, P O Box 848, Greenport, NY 11944 0848, USA
    Vet Immunol Immunopathol 88:131-48. 2002
    ..This study provides important information to further characterize the cutaneous DCs and develop models to analyze the role of these cells in immune responses in vivo...
  22. ncbi IL-13 replaces IL-4 in development of monocyte derived dendritic cells (MoDC) of swine
    Elida M Bautista
    Foot and Mouth Disease Research Unit, Plum Island Animal Disease Center, ARS, USDA, Greenport, NY 11944, USA
    Vet Immunol Immunopathol 115:56-67. 2007
    ..However, for swine, in vitro generation of MoDC in IL-13 is likely to induce a more physiological cell population to study given expression of IL-4 is lacking in the periphery of these animals...
  23. pmc Interactions of foot-and-mouth disease virus with soluble bovine alphaVbeta3 and alphaVbeta6 integrins
    Hernando Duque
    Foot and Mouth Disease Research Unit, Plum Island Animal Disease Center, USDA Agricultural Research Service, Greenport, NY 11944 0848, USA
    J Virol 78:9773-81. 2004
    ....