Research Topics
| Mendel FriedmanSummaryAffiliation: Agricultural Research Service Country: USA Publications
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Detail Information
Publications
Review of the inhibition of biological activities of food-related selected toxins by natural compoundsMendel Friedman
Produce Safety and Microbiology Research Unit, Agricultural Research Service, USDA, Albany, CA 94710, USA
Toxins (Basel) 5:743-75. 2013....
Nutritional and medicinal aspects of D-amino acidsMendel Friedman
Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA
Amino Acids 42:1553-82. 2012..The described results provide a valuable record and resource for further progress on the multifaceted aspects of D-amino acids in food and biological samples...
The olive compound 4-hydroxytyrosol inactivates Staphylococcus aureus bacteria and Staphylococcal Enterotoxin A (SEA)Mendel Friedman
Produce Safety and Microbiology Research Unit, Western Regional Research Center, Agricultural Research Service, U S Dept of Agriculture, 800 Buchanan Street, Albany, CA 94710, USA
J Food Sci 76:M558-63. 2011..Practical Application: The results of this study suggest that food-compatible and safe antitoxin olive compounds can be used to reduce both pathogens and toxins produced by the pathogens in foods...
Nutritional value of D-amino acids, D-peptides, and amino acid derivatives in miceMendel Friedman
United States Department of Agriculture, Western Regional Research Center, Agricultural Research Service, Albany, CA, USA
Methods Mol Biol 794:337-53. 2012....
Changes in the composition of raw tea leaves from the Korean Yabukida plant during high-temperature processing to pan-fried Kamairi-cha green teaMendel Friedman
Western Regional Research Center, U S Dept of Agriculture, Albany, CA, USA
J Food Sci 74:C406-12. 2009..The possible significance of the results for the human diet is discussed...
Tomatine-containing green tomato extracts inhibit growth of human breast, colon, liver, and stomach cancer cellsMendel Friedman
US Department of Agriculture, Agricultural Research Service, Western Regional Research Center, Albany, California 94710, USA
J Agric Food Chem 57:5727-33. 2009..Possible mechanisms of the anticarcinogenic and other beneficial effects and the significance of the cited observations for breeding improved tomatoes and for the human diet are discussed...
Stability of green tea catechins in commercial tea leaves during storage for 6 monthsMendel Friedman
US Dept of Agriculture, Albany, CA 94710, USA
J Food Sci 74:H47-51. 2009..Possible mechanisms of degradations of catechins during storage and the possible significance of the results to consumers of tea are discussed...
Origin, microbiology, nutrition, and pharmacology of D-amino acidsMendel Friedman
Western Regional Research Center, Agricultural Research Service, USDA, Albany, CA 94710, USA
Chem Biodivers 7:1491-530. 2010..Also covered are the origin and distribution of DAAs in food and possible roles of DAAs in human physiology, aging, and the etiology and therapy of human diseases...
Review of antimicrobial and antioxidative activities of chitosans in foodMendel Friedman
Produce Safety and Microbiology Research Unit, Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, Albany, California 94710, USA
J Food Prot 73:1737-61. 2010..We are very hopeful that the described findings will be a valuable record and resource for further progress to improve microbial food safety and food quality...
Antibacterial effects of allspice, garlic, and oregano essential oils in tomato films determined by overlay and vapor-phase methodsW X Du
Processed Foods Research, Western Regional Research Center, US Dept of Agriculture, Agricultural Research Service, 800 Buchanan St, Albany, CA 94710, USA
J Food Sci 74:M390-7. 2009....
Structure-activity relationships of tea compounds against human cancer cellsMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, Albany, California 94710, USA
J Agric Food Chem 55:243-53. 2007..The findings extend related observations on the anticarcinogenic potential of tea ingredients and suggest that consumers may benefit more by drinking both green and black teas...
Effects of allspice, cinnamon, and clove bud essential oils in edible apple films on physical properties and antimicrobial activitiesW X Du
Processed Foods Research, Western Regional Research Center, US Dept of Agriculture, Agricultural Research Service, 800 Buchanan St, Albany, CA 94710, USA
J Food Sci 74:M372-8. 2009..The results show that apple-based films with allspice, cinnamon, or clove bud oils were active against 3 foodborne pathogens by both direct contact with the bacteria and indirectly by vapors emanating from the films...
Carvacrol, cinnamaldehyde, oregano oil, and thymol inhibit Clostridium perfringens spore germination and outgrowth in ground turkey during chillingVijay K Juneja
Microbial Food Safety Research Unit, Eastern Regional Research Center, U S Department of Agriculture, Agricultural Research Service, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, USA
J Food Prot 70:218-22. 2007..5%) at the most abusive chilling rate evaluated (21 h). These findings establish the value of the plant-derived antimicrobials for inhibiting C. perfringens in commercial ground turkey products...
Control of Clostridium perfringens spores by green tea leaf extracts during cooling of cooked ground beef, chicken, and porkVijay K Juneja
Microbial Food Safety Research Unit, Eastern Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, USA
J Food Prot 70:1429-33. 2007..perfringens spore germination and outgrowth during abusive cooling from 54.4 to 7.2 degrees C in 12, 15, 18, or 21 h of cooling for ground beef, chicken, and pork...
Sensory evaluation of baked chicken wrapped with antimicrobial apple and tomato edible films formulated with cinnamaldehyde and carvacrolWen Xian Du
Processed Foods Research, Western Regional Research Center, Agricultural Research Service ARS, United States Department of Agriculture USDA, Albany, California 94710, United States
J Agric Food Chem 60:7799-804. 2012..Films containing antibacterial active compounds derived from essential oils can be used to protect raw chicken pieces against bacterial contamination without adversely affecting preferences of wrapped chicken pieces after baking...
Thermal destruction of Escherichia coli O157:H7 in sous-vide cooked ground beef as affected by tea leaf and apple skin powdersVijay K Juneja
Microbial Food Safety Research Unit, Eastern Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, USA
J Food Prot 72:860-5. 2009..Thermal death times from this study will assist the retail food industry to design cooking regimes that ensure the safety of beef contaminated with E. coli O157:H7...
Antimicrobial activities of tea catechins and theaflavins and tea extracts against Bacillus cereusMendel Friedman
Western Regional Research Center, Agricultural Research Service, US Department of Agriculture, Albany, California 94710, USA
J Food Prot 69:354-61. 2006..These studies extend our knowledge about the antimicrobial effects of food ingredients...
Control of Clostridium perfringens in cooked ground beef by carvacrol, cinnamaldehyde, thymol, or oregano oil during chillingVijay K Juneja
Microbial Food Safety Research Unit, Eastern Regional Research Center, U S Department of Agriculture, Agricultural Research Service, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, USA
J Food Prot 69:1546-51. 2006..Incorporation of lower levels of these test compounds with other antimicrobials used in meat product formulations may reduce the potential risk of C. perfringens germination and outgrowth during abusive cooling regimes...
Recipes for antimicrobial wine marinades against Bacillus cereus, Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella entericaMendel Friedman
Western Regional Research Center, Agricultural Research Service, US Department of Agriculture, Albany, CA 94710, USA
J Food Sci 72:M207-13. 2007..These observations suggest that antimicrobial wine formulations have the potential to improve the microbiological safety of foods...
Antibacterial activity against E. coli O157:H7, physical properties, and storage stability of novel carvacrol-containing edible tomato filmsW X Du
Western Regional Research Center, Processed Foods, Agricultural Research Service, USDA, Albany, CA 94710, USA
J Food Sci 73:M378-83. 2008..This 1st report on tomato-based edible antimicrobial tomato films suggests that these films have the potential to prevent adverse effects of contaminated food and promote human health associated with the consumption of tomatoes...
Inhibition of Shiga toxin 2 (Stx2) in apple juices and its resistance to pasteurizationReuven Rasooly
Foodborne Contaminants Research Units, Western Regional Research Center, Agricultural Research Service, U S Dept of Agriculture, Albany, CA, USA
J Food Sci 75:M296-301. 2010..The results suggest that pasteurization of apple juice used to inactivate E. coli O157:H7 has no effect on Stx2, and that food-compatible and safe antitoxin compounds can be used to inhibit the biological activity of the Shiga toxin...
Antibacterial activities of plant essential oils and their components against Escherichia coli O157:H7 and Salmonella enterica in apple juiceMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 800 Buchanan Street, Albany, California 94710, USA
J Agric Food Chem 52:6042-8. 2004..These studies provide information about new ways to protect apple juice and other foods against human pathogens...
Anticarcinogenic effects of glycoalkaloids from potatoes against human cervical, liver, lymphoma, and stomach cancer cellsMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, Albany, California 94710, USA
J Agric Food Chem 53:6162-9. 2005..The decreases in cell populations were also observed visually by reversed-phase microscopy. The results complement related observations on the anticarcinogenic potential of food ingredients...
Carvacrol and cinnamaldehyde facilitate thermal destruction of Escherichia coli O157:H7 in raw ground beefVijay K Juneja
U S Department of Agriculture, Agricultural Research Service, Microbial Food Safety Research Unit, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, USA
J Food Prot 71:1604-11. 2008..5 to 1.0%. The observed thermal death times may facilitate the design of acceptance limits at critical control points for ground beef at lower times and temperatures of heating...
Storage stability and antibacterial activity against Escherichia coli O157:H7 of carvacrol in edible apple films made by two different casting methodsWen Xian Du
Western Regional Research Center, Processed Foods and Produce Safety and Microbiology Research, Agricultural Research Service, United States Department of Agriculture USDA, Albany, California 94710, USA
J Agric Food Chem 56:3082-8. 2008..The cited observations facilitate relating compositional and physicochemical properties of apple puree films containing volatile plant antimicrobials to their use in foods...
Inhibition of biological activity of staphylococcal enterotoxin A (SEA) by apple juice and apple polyphenolsReuven Rasooly
Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, California 94710, USA
J Agric Food Chem 58:5421-6. 2010..The significance of the results for microbial food safety and human health is discussed...
Antibacterial activities of phenolic benzaldehydes and benzoic acids against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, and Salmonella entericaMendel Friedman
Western Regional Research Center, Agricultural Research Service, US Department of Agriculture, 800 Buchanan Street, Albany, California 94710, USA
J Food Prot 66:1811-21. 2003..enterica at pH 7.0 as it was at pH 3.7, suggesting that the ionization of its OH groups may enhance bactericidal activity...
Kinetics of thermal destruction of Salmonella in ground chicken containing trans-cinnamaldehyde and carvacrolVijay K Juneja
Eastern Regional Research Center, U S Department of Agriculture, Agricultural Research Service, Wyndmoor, PA 19038, USA
J Food Prot 75:289-96. 2012..Thermal death times from this study will be beneficial to the food industry in designing hazard analysis and critical control point plans to effectively eliminate Salmonella contamination in chicken products used in this study...
Biological effects of Maillard browning products that may affect acrylamide safety in food: biological effects of Maillard productsMendel Friedman
Western Regional Research Center, Agricultural Reseach Service, USDA, 800 Buchanan Street, Albany, CA 94710, USA
Adv Exp Med Biol 561:135-56. 2005..Such studies should lead to safer foods...
Antibacterial activities of naturally occurring compounds against antibiotic-resistant Bacillus cereus vegetative cells and spores, Escherichia coli, and Staphylococcus aureusMendel Friedman
Western Regional Research Center, Agricultural Research Service, US Department of Agriculture, Albany, California 94710, USA
J Food Prot 67:1774-8. 2004..cereus (vegetative) >> S. aureus approximately E. coli >> B. cereus (spores). Some of the test substances may be effective against antibiotic-resistant bacteria in foods and feeds...
Growth-inhibitory effects of pigmented rice bran extracts and three red bran fractions against human cancer cells: relationships with composition and antioxidative activitiesMing Hsuan Chen
Dale Bumpers National Rice Research Center, Agricultural Research Service, U S Department of Agriculture, 2890 Highway 130 East, Stuttgart, Arkansas 72160, USA
J Agric Food Chem 60:9151-61. 2012..The red bran was further fractionated on a Sephadex column. Fraction 3 rich in proanthocyanidin oligomers and polymers had the greatest activity. Red bran has the potential to serve as a functional food supplement for human consumption...
Analysis by HPLC and LC/MS of pungent piperamides in commercial black, white, green, and red whole and ground peppercornsMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, Albany, California 94710, USA
J Agric Food Chem 56:3028-36. 2008..These results demonstrate the utility of the described extraction and analytical methods used to determine the wide-ranging individual and total piperamide contents of widely consumed peppers...
Protective effect of dietary tomatine against dibenzo[a,l]pyrene (DBP)-induced liver and stomach tumors in rainbow troutMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, Albany, CA 94710, USA
Mol Nutr Food Res 51:1485-91. 2007..Dose-response and chemopreventive mechanisms for tomatine protection remain to be examined. This is the first report on the anticarcinogenic effects of tomatine in vivo...
Review of methods for the reduction of dietary content and toxicity of acrylamideMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, Albany, California 94710, USA
J Agric Food Chem 56:6113-40. 2008....
Nutritional consequences of food processingMendel Friedman
Western Regional Research Center, Agricultural Research Service, USDA, Albany, California 94710, USA
Forum Nutr 56:350-2. 2003..Possible approaches to prevent the formation of deleterious food ingredients are also addressed...
Glycoalkaloid and calystegine contents of eight potato cultivarsMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 800 Buchanan Street, Albany, CA 94710, USA
J Agric Food Chem 51:2964-73. 2003..The possible significance of the results to plant and food sciences is discussed...
Tomato glycoalkaloids: role in the plant and in the dietMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 800 Buchanan Street, Albany, California 94710, USA
J Agric Food Chem 50:5751-80. 2002..Such an understanding can lead to the creation of improved tomatoes and to improved practices on the farm and in the consumption of tomatoes...
Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teasMendel Friedman
Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA, USA
Mol Nutr Food Res 51:116-34. 2007..Further research is suggested for each of these categories. The herein described findings are not only of fundamental interest, but also have practical implications for nutrition, food safety, and animal and human health...
Milk inhibits the biological activity of ricinReuven Rasooly
Unit of Foodborne Contaminants, Agricultural Research Service, United States Department of Agriculture, Albany, California 94710, USA
J Biol Chem 287:27924-9. 2012..These observations suggest that ricin toxicity may possibly be reduced at room temperature by a widely consumed natural liquid food...
Carvacrol facilitates heat-induced inactivation of Escherichia coli O157:H7 and inhibits formation of heterocyclic amines in grilled ground beef pattiesMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, Albany, CA 94710, USA
J Agric Food Chem 57:1848-53. 2009..The results show that carvacrol concurrently reduced E. coli O157:H7 and amines in a widely consumed meat product. Possible mechanisms of the beneficial effects and dietary significance of the results are discussed...
Thermal inactivation and postthermal treatment growth during storage of multiple Salmonella serotypes in ground beef as affected by sodium lactate and oregano oilVijay K Juneja
Microbial Food Safety Research Unit, Eastern Regional Research Center, Agricultural Research Service, U S Dept of Agriculture, Wyndmoor, PA 19038, USA
J Food Sci 75:M1-6. 2010..These findings indicate that lactate and oregano oil may be used to render Salmonella spp. more susceptible to the lethal effect of heat and to inhibit growth of Salmonella spp. that survive heat treatments...
Predictive model for the reduction of heat resistance of Listeria monocytogenes in ground beef by the combined effect of sodium chloride and apple polyphenolsVijay K Juneja
U S Department of Agriculture, Agricultural Research Service, Eastern Regional Research Center, 600 E Mermaid Lane, Wyndmoor, PA 19038, USA Electronic address
Int J Food Microbiol 164:54-9. 2013..Additional benefits include reduced energy use in cooking, and the addition of antioxidative apple polyphenols may provide beneficial health affects to consumers...
Bactericidal activities of plant essential oils and some of their isolated constituents against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, and Salmonella entericaMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, Albany, California 94710, USA
J Food Prot 65:1545-60. 2002..034 to 0.21) were thymol, cinnamaldehyde, carvacrol, eugenol, salicylaldehyde, geraniol, isoeugenol, terpineol, perillaldehyde, and estragole. The possible significance of these results with regard to food microbiology is discussed...
Analysis of biologically active compounds in potatoes (Solanum tuberosum), tomatoes (Lycopersicon esculentum), and jimson weed (Datura stramonium) seedsMendel Friedman
Western Regional Research Center, Agricultural Research Service, US Department of Agriculture, Albany, CA 94710, USA
J Chromatogr A 1054:143-55. 2004..Related studies by other investigators are also mentioned. Accurate analytical methods for these food ingredients help assure the consumer of eating a good-quality and safe diet...
Effect of feeding solanidine, solasodine and tomatidine to non-pregnant and pregnant miceMendel Friedman
Western Regional Research Center, Agricultural Research Service, USDA, 800 Buchanan Street, Albany, CA 94710, USA
Food Chem Toxicol 41:61-71. 2003..Generally, the biological effects of solanidine differ from those of the parent potato glycoalkaloids. Possible mechanisms of these effects and the implication of the results for food safety and plant physiology are discussed...
Potato glycoalkaloids and metabolites: roles in the plant and in the dietMendel Friedman
Western Regional Research Center, Agricultural Research Service, U.S. Department of Agriculture, Albany, California 94710, USA
J Agric Food Chem 54:8655-81. 2006..An enhanced understanding of the multiple and overlapping aspects of glycoalkaloids in the plant and in the diet will benefit producers and consumers of potatoes...
Ingested Shiga toxin 2 (Stx2) causes histopathological changes in kidney, spleen, and thymus tissues and mortality in miceReuven Rasooly
Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, California 94710, USA
J Agric Food Chem 58:9281-6. 2010..The results are clinically relevant for food safety because we also found that heat treatments (pasteurization) that destroy bacteria did not inactivate the heat-resistant toxin produced and secreted by the bacteria...
Bactericidal Activities of Health-Promoting, Food-Derived Powders Against the Foodborne Pathogens Escherichia coli, Listeria monocytogenes, Salmonella enterica, and Staphylococcus aureusMendel Friedman
Western Regional Research Center, Agricultural Research Service USDA, Produce Safety and Microbiology Research Unit, Albany, CA, 94710, U S A
J Food Sci 78:M270-5. 2013..Practical Application: Plant-derived health-promoting food supplements, high in bioactive compounds, are candidates for use as antimicrobials in food...
Novel cell-based method to detect Shiga toxin 2 from Escherichia coli O157:H7 and inhibitors of toxin activityBeatriz Quiñones
US Department of Agriculture, Agricultural Research Service, Western Regional Research Center, Produce Safety and Microbiology Research Unit, Albany, California, USA
Appl Environ Microbiol 75:1410-6. 2009..These results indicate that the Vero-d2EGFP fluorescence assay is an accurate and sensitive method to detect Stx2 activity and can be utilized to identify toxin inhibitors...
Applications of the ninhydrin reaction for analysis of amino acids, peptides, and proteins to agricultural and biomedical sciencesMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 800 Buchanan Street, Albany, California 94710, USA
J Agric Food Chem 52:385-406. 2004..A better understanding of these multifaceted ninhydrin reactions provide a scientific basis for further improvements of this important analytical technique...
Chemistry, biochemistry, and safety of acrylamide. A reviewMendel Friedman
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 800 Buchanan Street, Albany, California 94710, USA
J Agric Food Chem 51:4504-26. 2003..A better understanding of the chemistry and biology of pure acrylamide in general and its impact in a food matrix in particular can lead to the development of improved food processes to decrease the acrylamide content of the diet...
Immunoassays of soy proteinsDavid L Brandon
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 800 Buchanan Street, Albany, California 94710, USA
J Agric Food Chem 50:6635-42. 2002....
