Scott R Baerson

Summary

Affiliation: Agricultural Research Service
Country: USA

Publications

  1. ncbi request reprint A functional genomics investigation of allelochemical biosynthesis in Sorghum bicolor root hairs
    Scott R Baerson
    United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, University, Mississippi 38677, USA
    J Biol Chem 283:3231-47. 2008
  2. pmc Alkylresorcinol synthases expressed in Sorghum bicolor root hairs play an essential role in the biosynthesis of the allelopathic benzoquinone sorgoleone
    Daniel Cook
    U S Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, University, Mississippi 38677, USA
    Plant Cell 22:867-87. 2010
  3. pmc Alkylresorcinol biosynthesis in plants: new insights from an ancient enzyme family?
    Scott R Baerson
    United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, MS, USA
    Plant Signal Behav 5:1286-9. 2010
  4. ncbi request reprint Functional characterization of desaturases involved in the formation of the terminal double bond of an unusual 16:3Delta(9,12,150) fatty acid isolated from Sorghum bicolor root hairs
    Zhiqiang Pan
    United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, University of Mississippi, University, Mississippi 38677, USA
    J Biol Chem 282:4326-35. 2007
  5. doi request reprint In planta production of the highly potent resveratrol analogue pterostilbene via stilbene synthase and O-methyltransferase co-expression
    Agnes M Rimando
    Natural Products Utilization Research Unit, Agricultural Research Service, United States Department of Agriculture, University, MS, USA
    Plant Biotechnol J 10:269-83. 2012
  6. doi request reprint Sorgoleone
    Franck E Dayan
    United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, P O Box 8048, University, MS 38677, USA
    Phytochemistry 71:1032-9. 2010
  7. ncbi request reprint Detoxification and transcriptome response in Arabidopsis seedlings exposed to the allelochemical benzoxazolin-2(3H)-one
    Scott R Baerson
    Agricultural Research Service, Natural Products Utilization Research Unit, United States Department of Agriculture, PO Box 8048, University, MS 38677, USA
    J Biol Chem 280:21867-81. 2005
  8. pmc Saururus cernuus lignans--potent small molecule inhibitors of hypoxia-inducible factor-1
    Chowdhury Faiz Hossain
    Department of Pharmacognosy, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, MS 38677 1848, USA
    Biochem Biophys Res Commun 333:1026-33. 2005
  9. pmc A potent plant-derived antifungal acetylenic acid mediates its activity by interfering with fatty acid homeostasis
    Tao Xu
    National Center for Natural Products Research, University of Mississippi, University, Mississippi, USA
    Antimicrob Agents Chemother 56:2894-907. 2012
  10. ncbi request reprint United States Department of Agriculture-Agricultural Research Service research on natural products for pest management
    Stephen O Duke
    USDA, ARS, Natural Products Utilization Research Unit, PO Box 8048, University, MS 38677, USA
    Pest Manag Sci 59:708-17. 2003

Detail Information

Publications13

  1. ncbi request reprint A functional genomics investigation of allelochemical biosynthesis in Sorghum bicolor root hairs
    Scott R Baerson
    United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, University, Mississippi 38677, USA
    J Biol Chem 283:3231-47. 2008
    ..SbOMT3 is therefore proposed to be involved in the biosynthesis of the allelochemical sorgoleone...
  2. pmc Alkylresorcinol synthases expressed in Sorghum bicolor root hairs play an essential role in the biosynthesis of the allelopathic benzoquinone sorgoleone
    Daniel Cook
    U S Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, University, Mississippi 38677, USA
    Plant Cell 22:867-87. 2010
    ..The sequences of ARS1 and ARS2 were also used to identify several rice (Oryza sativa) genes encoding ARSs, which are likely involved in the production of defense-related alkylresorcinols...
  3. pmc Alkylresorcinol biosynthesis in plants: new insights from an ancient enzyme family?
    Scott R Baerson
    United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, MS, USA
    Plant Signal Behav 5:1286-9. 2010
    ....
  4. ncbi request reprint Functional characterization of desaturases involved in the formation of the terminal double bond of an unusual 16:3Delta(9,12,150) fatty acid isolated from Sorghum bicolor root hairs
    Zhiqiang Pan
    United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, University of Mississippi, University, Mississippi 38677, USA
    J Biol Chem 282:4326-35. 2007
    ..Collectively, the present results strongly suggest that these fatty acid desaturases represent key enzymes involved in the biosynthesis of the allelochemical sorgoleone...
  5. doi request reprint In planta production of the highly potent resveratrol analogue pterostilbene via stilbene synthase and O-methyltransferase co-expression
    Agnes M Rimando
    Natural Products Utilization Research Unit, Agricultural Research Service, United States Department of Agriculture, University, MS, USA
    Plant Biotechnol J 10:269-83. 2012
    ....
  6. doi request reprint Sorgoleone
    Franck E Dayan
    United States Department of Agriculture, Agricultural Research Service, Natural Products Utilization Research Unit, P O Box 8048, University, MS 38677, USA
    Phytochemistry 71:1032-9. 2010
    ..Due to its hydrophobic nature, sorgoleone is strongly sorbed in soil which increases its persistence, but experiments show that it is mineralized by microorganisms over time...
  7. ncbi request reprint Detoxification and transcriptome response in Arabidopsis seedlings exposed to the allelochemical benzoxazolin-2(3H)-one
    Scott R Baerson
    Agricultural Research Service, Natural Products Utilization Research Unit, United States Department of Agriculture, PO Box 8048, University, MS 38677, USA
    J Biol Chem 280:21867-81. 2005
    ..The data significantly expand upon previous studies examining plant transcriptional responses to allelochemicals and other environmental toxins and provide novel insights into xenobiotic detoxification mechanisms in plants...
  8. pmc Saururus cernuus lignans--potent small molecule inhibitors of hypoxia-inducible factor-1
    Chowdhury Faiz Hossain
    Department of Pharmacognosy, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University, MS 38677 1848, USA
    Biochem Biophys Res Commun 333:1026-33. 2005
    ..In addition, preliminary structure-activity studies suggest specific structural requirements for this class of HIF-1 inhibitors...
  9. pmc A potent plant-derived antifungal acetylenic acid mediates its activity by interfering with fatty acid homeostasis
    Tao Xu
    National Center for Natural Products Research, University of Mississippi, University, Mississippi, USA
    Antimicrob Agents Chemother 56:2894-907. 2012
    ..albicans. Collectively, our results indicate that the antifungal activity of 6-NDA is mediated by a disruption in fatty acid homeostasis and that 6-NDA has potential utility in the treatment of superficial Candida infections...
  10. ncbi request reprint United States Department of Agriculture-Agricultural Research Service research on natural products for pest management
    Stephen O Duke
    USDA, ARS, Natural Products Utilization Research Unit, PO Box 8048, University, MS 38677, USA
    Pest Manag Sci 59:708-17. 2003
    ..Gene expression profiles in response to fungicides and herbicides are being generated as tools to understand more fully the mode of action and to rapidly determine the molecular target site of new, natural fungicides and herbicides...
  11. pmc Hypoxia-inducible factor-1 activation by (-)-epicatechin gallate: potential adverse effects of cancer chemoprevention with high-dose green tea extracts
    Yu Dong Zhou
    National Center for Natural Products Research and Department of Pharmacognosy, Research Institute of Pharmaceutical Sciences, School of Pharmacy, P O Box 1848, University of Mississippi, University, Mississippi 38677, USA
    J Nat Prod 67:2063-9. 2004
    ..These results suggest that intended cancer chemoprevention with high-dose green tea extracts may be compromised, by the ability of tea catechins to promote tumor cell survival pathways associated with HIF-1 activation...
  12. ncbi request reprint Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae
    Ameeta K Agarwal
    National Center for Natural Products Research, University of Mississippi School of Pharmacy, University, Mississippi 38677, USA
    J Biol Chem 278:34998-5015. 2003
    ..Taken together, these data shed new light on the mechanisms of action of these classes of antifungal agents and demonstrate the potential utility of gene expression profiling in antifungal drug development...
  13. pmc Glyphosate-resistant goosegrass. Identification of a mutation in the target enzyme 5-enolpyruvylshikimate-3-phosphate synthase
    Scott R Baerson
    Monsanto Company, 700 Chesterfield Parkway North, St Louis, Missouri 63198, USA
    Plant Physiol 129:1265-75. 2002
    ..These results provide the first evidence for an altered EPSPS enzyme as an underlying component of evolved glyphosate resistance in any plant species...