R A Anderson

Summary

Affiliation: Agricultural Research Service
Country: USA

Publications

  1. ncbi request reprint Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes
    R A Anderson
    Beltsville Human Nutrition Research Center, U S Department of Agriculture, Maryland 20705 2350, USA
    Diabetes 46:1786-91. 1997
  2. ncbi request reprint Chromium in the prevention and control of diabetes
    R A Anderson
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research, U S Department of Agriculture, ARS, Beltsville, Maryland 20705 2350, USA
    Diabetes Metab 26:22-7. 2000
  3. ncbi request reprint Potential antioxidant effects of zinc and chromium supplementation in people with type 2 diabetes mellitus
    R A Anderson
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, USDA, ARS, MD 20705, USA
    J Am Coll Nutr 20:212-8. 2001
  4. doi request reprint Chromium and polyphenols from cinnamon improve insulin sensitivity
    Richard A Anderson
    Beltsville Human Nutrition Research Center, USDA, Beltsville, MD 20705, USA
    Proc Nutr Soc 67:48-53. 2008
  5. ncbi request reprint Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity
    Richard A Anderson
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, USDA, ARS, Bldg 307C, Rm 223, Beltsville, Maryland 20705 2350, USA
    J Agric Food Chem 52:65-70. 2004
  6. doi request reprint A procyanidin type A trimer from cinnamon extract attenuates glial cell swelling and the reduction in glutamate uptake following ischemia-like injury in vitro
    K S Panickar
    United States Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Beltsville, MD 20705, USA
    Neuroscience 202:87-98. 2012
  7. ncbi request reprint Tea enhances insulin activity
    Richard A Anderson
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, U S Department of Agriculture, Beltsville, Maryland 20705, USA
    J Agric Food Chem 50:7182-6. 2002
  8. doi request reprint Green tea polyphenols improve cardiac muscle mRNA and protein levels of signal pathways related to insulin and lipid metabolism and inflammation in insulin-resistant rats
    Bolin Qin
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD 20705, USA
    Mol Nutr Food Res 54:S14-23. 2010
  9. doi request reprint Cinnamon extract regulates plasma levels of adipose-derived factors and expression of multiple genes related to carbohydrate metabolism and lipogenesis in adipose tissue of fructose-fed rats
    B Qin
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, Maryland 20705, USA
    Horm Metab Res 42:187-93. 2010
  10. doi request reprint Elevation of tumor necrosis factor-alpha induces the overproduction of postprandial intestinal apolipoprotein B48-containing very low-density lipoprotein particles: evidence for related gene expression of inflammatory, insulin and lipoprotein signaling in
    Bolin Qin
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, Building 307C, 10300 Baltimore Avenue, Beltsville, MD 20705 2350, USA
    Exp Biol Med (Maywood) 235:199-205. 2010

Collaborators

Detail Information

Publications61

  1. ncbi request reprint Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes
    R A Anderson
    Beltsville Human Nutrition Research Center, U S Department of Agriculture, Maryland 20705 2350, USA
    Diabetes 46:1786-91. 1997
    ..The beneficial effects of chromium in individuals with diabetes were observed at levels higher than the upper limit of the Estimated Safe and Adequate Daily Dietary Intake...
  2. ncbi request reprint Chromium in the prevention and control of diabetes
    R A Anderson
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research, U S Department of Agriculture, ARS, Beltsville, Maryland 20705 2350, USA
    Diabetes Metab 26:22-7. 2000
    ..Additional studies are urgently needed to elucidate the mechanism of action of chromium and its role in the prevention and control of diabetes...
  3. ncbi request reprint Potential antioxidant effects of zinc and chromium supplementation in people with type 2 diabetes mellitus
    R A Anderson
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, USDA, ARS, MD 20705, USA
    J Am Coll Nutr 20:212-8. 2001
    ..To determine the effects of combined zinc (Zn) and chromium (Cr) supplementation on oxidative stress and glucose homeostasis of people with type 2 diabetes...
  4. doi request reprint Chromium and polyphenols from cinnamon improve insulin sensitivity
    Richard A Anderson
    Beltsville Human Nutrition Research Center, USDA, Beltsville, MD 20705, USA
    Proc Nutr Soc 67:48-53. 2008
    ....
  5. ncbi request reprint Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity
    Richard A Anderson
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, USDA, ARS, Bldg 307C, Rm 223, Beltsville, Maryland 20705 2350, USA
    J Agric Food Chem 52:65-70. 2004
    ..These polyphenolic polymers found in cinnamon may function as antioxidants, potentiate insulin action, and may be beneficial in the control of glucose intolerance and diabetes...
  6. doi request reprint A procyanidin type A trimer from cinnamon extract attenuates glial cell swelling and the reduction in glutamate uptake following ischemia-like injury in vitro
    K S Panickar
    United States Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics and Immunology Laboratory, Beltsville, MD 20705, USA
    Neuroscience 202:87-98. 2012
    ..Thus, the effects of trimer 1 in attenuating the reduction in glutamate uptake are likely mediated through their action on the mitochondria...
  7. ncbi request reprint Tea enhances insulin activity
    Richard A Anderson
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, U S Department of Agriculture, Beltsville, Maryland 20705, USA
    J Agric Food Chem 50:7182-6. 2002
    ..Nondairy creamers and soy milk also decreased the insulin-enhancing activity. These data demonstrate that tea contains in vitro insulin-enhancing activity and the predominant active ingredient is epigallocatechin gallate...
  8. doi request reprint Green tea polyphenols improve cardiac muscle mRNA and protein levels of signal pathways related to insulin and lipid metabolism and inflammation in insulin-resistant rats
    Bolin Qin
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD 20705, USA
    Mol Nutr Food Res 54:S14-23. 2010
    ..In summary, consumption of GTP ameliorated the detrimental effects of high-fructose diet on insulin signaling, lipid metabolism and inflammation in the cardiac muscle of rats...
  9. doi request reprint Cinnamon extract regulates plasma levels of adipose-derived factors and expression of multiple genes related to carbohydrate metabolism and lipogenesis in adipose tissue of fructose-fed rats
    B Qin
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, Maryland 20705, USA
    Horm Metab Res 42:187-93. 2010
    ..These results suggest that CE effectively ameliorates circulating levels of adipokines partially mediated via regulation of the expression of multiple genes involved in insulin sensitivity and lipogenesis in the EAT...
  10. doi request reprint Elevation of tumor necrosis factor-alpha induces the overproduction of postprandial intestinal apolipoprotein B48-containing very low-density lipoprotein particles: evidence for related gene expression of inflammatory, insulin and lipoprotein signaling in
    Bolin Qin
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, Building 307C, 10300 Baltimore Avenue, Beltsville, MD 20705 2350, USA
    Exp Biol Med (Maywood) 235:199-205. 2010
    ..These findings provide mechanistic links among the inflammatory factor, TNF-alpha, intestinal inflammatory/insulin insensitivity and the overproduction of intestinal apoB48-containing lipoproteins...
  11. doi request reprint A polyphenol mixture from cinnamon targets p38 MAP kinase-regulated signaling pathways to produce G2/M arrest
    Norberta W Schoene
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, ARS, USDA, Beltsville, MD 20705 2350, USA
    J Nutr Biochem 20:614-20. 2009
    ..Overall, the data provide evidence that CE affects proliferation in a leukemic cell line by disrupting critical phosphorylating/dephosphorylating signaling events that propel cells through the G2/M phase...
  12. doi request reprint Insulin increases tristetraprolin and decreases VEGF gene expression in mouse 3T3-L1 adipocytes
    Heping Cao
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, Maryland, USA
    Obesity (Silver Spring) 16:1208-18. 2008
    ..We analyzed the relative abundance of TTP family mRNAs in 3T3-L1 adipocytes compared to RAW264.7 macrophages and investigated insulin effects on the expression of 43 genes in 3T3-L1 adipocytes...
  13. pmc Production and characterization of ZFP36L1 antiserum against recombinant protein from Escherichia coli
    Heping Cao
    Diet, Genomics and Immunology Laboratory, Beltsville Human Nutrition Research Center, U S Department of Agriculture ARS, 10300 Baltimore Avenue, Beltsville, MD 20705, USA
    Biotechnol Prog 24:326-33. 2008
    ..These results demonstrate that ZFP36L1 antiserum is useful in the detection of this protein and that TTP and ZFP36L1 are differentially expressed and regulated at the mRNA and protein levels in mouse adipocytes and macrophages...
  14. ncbi request reprint Green tea polyphenol extract regulates the expression of genes involved in glucose uptake and insulin signaling in rats fed a high fructose diet
    Heping Cao
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, U S Department of Agriculture, Beltsville, Maryland 20705, USA
    J Agric Food Chem 55:6372-8. 2007
    ..This study shows that green tea extract at 1 or 2 g/kg diet regulates gene expression in the glucose uptake and insulin signaling pathway in rats fed a fructose-rich diet...
  15. ncbi request reprint Water-soluble polymeric polyphenols from cinnamon inhibit proliferation and alter cell cycle distribution patterns of hematologic tumor cell lines
    Norberta W Schoene
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, ARS, USDA, Bldg 307C, Rm 227, BARC East, Beltsville, MD 20705 2350, USA
    Cancer Lett 230:134-40. 2005
    ..The results suggest the potential of CE to interact with phosphorylation/dephosphorylation signaling activities to reduce cellular proliferation in tandem with a block at the G2/M phase of the cell cycle...
  16. ncbi request reprint Burn-induced alterations of chromium and the glucose/insulin system in rats
    Richard A Anderson
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, Agriculture Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Burns 32:46-51. 2006
    ..These observations strongly suggest a mobilization and utilization of Cr following severe burn. Additional studies are needed to document that improved Cr status might lead to improved recovery following burn...
  17. doi request reprint Cinnamon extract inhibits the postprandial overproduction of apolipoprotein B48-containing lipoproteins in fructose-fed animals
    Bolin Qin
    Beltsville Human Nutrition Research Center, Agricultural Research Service, U S Department of Agriculture, Beltsville, MD 20705, USA
    J Nutr Biochem 20:901-8. 2009
    ....
  18. doi request reprint Cinnamon polyphenols attenuate cell swelling and mitochondrial dysfunction following oxygen-glucose deprivation in glial cells
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, 10300 Baltimore Ave, Bldg 307C, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Exp Neurol 216:420-7. 2009
    ..Our results show that CPE reduces OGD-induced cell swelling as well as the decline in DeltaPsi(m) in cultures and some of its protective effects may be through inhibiting the mPT...
  19. ncbi request reprint Cinnamon polyphenol extract affects immune responses by regulating anti- and proinflammatory and glucose transporter gene expression in mouse macrophages
    Heping Cao
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, USDA, Beltsville, MD 20705 2350, USA
    J Nutr 138:833-40. 2008
    ..These results suggest that CPE can affect immune responses by regulating anti- and proinflammatory and GLUT gene expression...
  20. doi request reprint Cinnamon polyphenol extract regulates tristetraprolin and related gene expression in mouse adipocytes
    Heping Cao
    Commodity Utilization Research Unit, Southern Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 1100 Robert E Lee Boulevard, New Orleans, Louisiana 70124, United States
    J Agric Food Chem 59:2739-44. 2011
    ..This study demonstrated that CPE rapidly induces TTP mRNA and reduces VEGF mRNA and affects the expression of a number of other genes in the cultured adipocytes...
  21. doi request reprint Cinnamon extract regulates glucose transporter and insulin-signaling gene expression in mouse adipocytes
    Heping Cao
    Commodity Utilization Research Unit, Southern Regional Research Center, Agricultural Research Service, US Department of Agriculture, 1100 Robert E Lee Blvd, New Orleans, LA 70124, USA
    Phytomedicine 17:1027-32. 2010
    ..This study indicates that CE regulates the expression of multiple genes in adipocytes and this regulation could contribute to the potential health benefits of CE...
  22. ncbi request reprint Role of dietary polyphenols in attenuating brain edema and cell swelling in cerebral ischemia
    Kiran S Panickar
    Department of Agriculture, Diet, Genomics, and Immunology Laboratory, Agricultural Research Service, Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA
    Recent Pat CNS Drug Discov 5:99-108. 2010
    ..A review of currently known mechanisms underlying edema/cell swelling will be undertaken and the potential of dietary polyphenols to reduce edema will be critically reviewed with the discussion of some recent patents...
  23. doi request reprint Green tea polyphenols attenuate glial swelling and mitochondrial dysfunction following oxygen-glucose deprivation in cultures
    Kiran S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705, USA
    Nutr Neurosci 12:105-13. 2009
    ..It appears that effects on cell swelling are mediated by the concerted action of more than one of the individual components of GTE...
  24. ncbi request reprint Cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3-L1 adipocytes
    Heping Cao
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD 20705 2350, USA
    Arch Biochem Biophys 459:214-22. 2007
    ..These results suggest that cinnamon exhibits the potential to increase the amount of proteins involved in insulin signaling, glucose transport, and anti-inflammatory/anti-angiogenesis response...
  25. ncbi request reprint Cinnamon extract attenuates TNF-alpha-induced intestinal lipoprotein ApoB48 overproduction by regulating inflammatory, insulin, and lipoprotein pathways in enterocytes
    B Qin
    U S Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Diet, Genomics, and Immunology Laboratory, Beltsville, Maryland 20705, USA
    Horm Metab Res 41:516-22. 2009
    ..In conclusion, Cinulin PF improves inflammation related intestinal dyslipidemia...
  26. doi request reprint Mechanisms underlying the protective effects of myricetin and quercetin following oxygen-glucose deprivation-induced cell swelling and the reduction in glutamate uptake in glial cells
    K S Panickar
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA
    Neuroscience 183:1-14. 2011
    ..The differential effects of myricetin and quercetin on OGD-induced reduction on glutamate uptake may be due to their differential effects on mitochondria...
  27. pmc Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes
    Bolin Qin
    Diet, Genomics, and Immunology Laboratory, Beltsville Human Nutrition Research Center, United States Department of Agriculture, Agricultural Research Service, Beltsville, Maryland 20705 2350, USA
    J Diabetes Sci Technol 4:685-93. 2010
    ..In summary, components of cinnamon may be important in the alleviation and prevention of the signs and symptoms of metabolic syndrome, type 2 diabetes, and cardiovascular and related diseases...
  28. ncbi request reprint Apparent mineral retention is similar in control and hyperinsulinemic men after consumption of high amylose cornstarch
    Kay M Behall
    Diet and Human Performance, Beltsville Human Nutrition Research Center, Agricultural Research Service, U S Department of Agriculture, MD, USA
    J Nutr 132:1886-91. 2002
    ..In summary, a high amylose cornstarch diet containing 30 g RS could be consumed long term without markedly affecting, and possibly enhancing, retention of some minerals...
  29. ncbi request reprint Stability and absorption of chromium and absorption of chromium histidinate complexes by humans
    Richard A Anderson
    Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, Beltsville, MD 20705, USA
    Biol Trace Elem Res 101:211-8. 2004
    ..Chromium histidinate complexes are absorbed better than any of the Cr complexes currently available and need to be evaluated as Cr nutritional supplements...
  30. ncbi request reprint Beneficial effects of hormonal replacement therapy on chromium status and glucose and lipid metabolism in postmenopausal women
    Anne Marie Roussel
    LBSO, Universite Joseph Fourier, Domaine de la Merci, La Tronche, France
    Maturitas 42:63-9. 2002
    ....
  31. ncbi request reprint The effect of cinnamon extract on insulin resistance parameters in polycystic ovary syndrome: a pilot study
    Jeff G Wang
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, College of Physicians and Surgeons, Columbia University, New York, New York 10023, USA
    Fertil Steril 88:240-3. 2007
    ..A larger trial is needed to confirm the findings of this pilot study and to evaluate the effect of cinnamon extract on menstrual cyclicity...
  32. ncbi request reprint Phosphatidylinositol phosphate kinase type Igamma directly associates with and regulates Shp-1 tyrosine phosphatase
    Shawn F Bairstow
    Department of Pharmacology, University of Wisconsin Medical School, Madison, Wisconsin 53706, USA
    J Biol Chem 280:23884-91. 2005
    ..These combined results suggest a model in which the reciprocal actions of Src tyrosine kinase and Shp-1 tyrosine phosphatase dynamically regulate the association between PIPKI gamma661 and talin...
  33. ncbi request reprint Prostaglandin E2 mediates phosphorylation and down-regulation of the tuberous sclerosis-2 tumor suppressor (tuberin) in human endometrial adenocarcinoma cells via the Akt signaling pathway
    Kurt J Sales
    MRC Human Reproductive Sciences Unit, Center for Reproductive Biology, The University of Edinburgh Academic Center, Edinburgh EH16 4SB, United Kingdom
    J Clin Endocrinol Metab 89:6112-8. 2004
    ..These data suggest that PGE2 signaling may promote endometrial tumorigenesis by inactivation of tuberin after its phosphorylation via the Akt signaling pathway...
  34. ncbi request reprint Localization and quantification of cyclic changes in the expression of endocrine gland vascular endothelial growth factor in the human corpus luteum
    Hamish M Fraser
    Medical Research Council Human Reproductive Sciences Unit, Centre for Reproductive Biology, Edinburgh, Scotland, United Kingdom
    J Clin Endocrinol Metab 90:427-34. 2005
    ..These results establish that in the human corpus luteum EG-VEGF is principally derived from granulosa lutein cells and that its synthesis is highest during the mid- to late luteal phase...
  35. ncbi request reprint Cinnamon improves glucose and lipids of people with type 2 diabetes
    Alam Khan
    Department of Human Nutrition, NWFP Agricultural University, Peshawar, Pakistan
    Diabetes Care 26:3215-8. 2003
    ..The objective of this study was to determine whether cinnamon improves blood glucose, triglyceride, total cholesterol, HDL cholesterol, and LDL cholesterol levels in people with type 2 diabetes...
  36. ncbi request reprint The human fetal testis is a site of expression of neurotrophins and their receptors: regulation of the germ cell and peritubular cell population
    Lynne L L Robinson
    Medical Research Council Human Reproductive Sciences Unit, Centre for Reproductive Biology, Edinburgh EH16 4SB, United Kingdom
    J Clin Endocrinol Metab 88:3943-51. 2003
    ..These data demonstrate the expression of NTs and their receptors in the human fetal testis during the second trimester and indicate possible roles in the regulation of proliferation and survival of germ cells and peritubular cells...
  37. ncbi request reprint Antioxidant effects of zinc supplementation in Tunisians with type 2 diabetes mellitus
    Anne Marie Roussel
    LBSO, Oxidative Stress Laboratory, Joseph Fourier University, Grenoble, France
    J Am Coll Nutr 22:316-21. 2003
    ..To determine the effects of zinc (Zn) supplementation on oxidative stress in persons with type 2 diabetes mellitus (type 2 DM)...
  38. ncbi request reprint Food chromium content, dietary chromium intake and related biological variables in French free-living elderly
    Anne Marie Roussel
    Laboratoire NVMC, EA 3746 Université Joseph Fourier, 38700, Grenoble, France
    Br J Nutr 98:326-31. 2007
    ..The low Cr intakes were due to the low Cr density of the foods. We found a negative correlation between Cr intakes and insulin, BMI and leptin...
  39. ncbi request reprint Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling
    Renee L Doughman
    Molecular and Cellular Pharmacology Program, Department of Pharmacology, University of Wisconsin Medical School, Madison, Wisconsin 53706, USA
    J Biol Chem 278:23036-45. 2003
    ..Combined, these data support a model where the localized production of PIP2 by PIPKIalpha is necessary for actin remodeling, whereas formation of membrane ruffles required Rac signaling...
  40. ncbi request reprint Prospective analysis of the relationships between the ovarian follicle cohort and basal FSH concentration, the inhibin response to exogenous FSH and ovarian follicle number at different stages of the normal menstrual cycle and after pituitary down-regulat
    Peter Y K Yong
    Royal Infirmary of Edinburgh, University of Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK
    Hum Reprod 18:35-44. 2003
    ..We have carried out a prospective analysis of endocrine and biophysical assessments under three differing basal conditions: the early follicular and mid-luteal phases, and following GnRH analogue down-regulation...
  41. ncbi request reprint Effects of resistive training and chromium picolinate on body composition and skeletal muscle size in older women
    Wayne W Campbell
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
    Int J Sport Nutr Exerc Metab 12:125-35. 2002
    ..Further, these data show that, under these experimental conditions, whole body composition and skeletal muscle size were not significantly changed due to resistive training and were not influenced by supplemental chromium picolinate...
  42. ncbi request reprint Trace mineral status in post menopausal women: impact of hormonal replacement therapy
    Isabelle Bureau
    Laboratoire de Biologie du Stress Oxydant, J Fourier University, Domaine de la Merci, La Tronche, France
    J Trace Elem Med Biol 16:9-13. 2002
    ..The HRT group also exhibited lower losses of urinary zinc and magnesium than untreated women. These data suggest that hormonal replacement therapy provides beneficial effects on trace mineral status related to menopause...
  43. ncbi request reprint Neurotropins and their receptors are expressed in the human fetal ovary
    Richard A Anderson
    Medical Research Council Human Reproductive Sciences Unit, Center for Reproductive Biology, University of Edinburgh, Edinburgh, United Kingdom EH3 9ET
    J Clin Endocrinol Metab 87:890-7. 2002
    ....
  44. ncbi request reprint Acute prooxidant effects of vitamin C in EDTA chelation therapy and long-term antioxidant benefits of therapy
    Isabelle Hininger
    Laboratoire NVMC Nutrition, Vieillissement, Maladies Cardiovasculaires, EA 3746, J Fourier University, Domaine de la Merci, 38700 La Tronche, France
    Free Radic Biol Med 38:1565-70. 2005
    ..However, standard high amounts of vitamin C added to EDTA chelation solutions also display short term prooxidant effects. The added benefits of lower levels of vitamin C in chelation therapy need to be documented...
  45. doi request reprint Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling
    Bolin Qin
    Department of Laboratory Medicine and Pathobiology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    Am J Physiol Gastrointest Liver Physiol 294:G1120-9. 2008
    ....
  46. pmc CKIalpha is associated with and phosphorylates star-PAP and is also required for expression of select star-PAP target messenger RNAs
    Michael L Gonzales
    Molecular and Cellular Pharmacology Training Program, Department of Pharmacology, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Biol Chem 283:12665-73. 2008
    ..The Star-PAP complex therefore represents a location where multiple signaling pathways converge to regulate the expression of specific mRNAs...
  47. ncbi request reprint Type Igamma661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis
    Shawn F Bairstow
    Department of Pharmacology, University of Wisconsin Medical School, Madison, Wisconsin 53706, USA
    J Biol Chem 281:20632-42. 2006
    ..Collectively, this evidence implies an important role for PIPKIgamma661 in the AP2-mediated endocytosis of transferrin...
  48. ncbi request reprint Is atrial fibrillation an inflammatory disorder?
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, UK
    Eur Heart J 27:136-49. 2006
    ....
  49. pmc Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the human
    Nina Hallmark
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, Queen s Medical Research Institute, Edinburgh, United Kingdom
    Environ Health Perspect 115:390-6. 2007
    ..Certain phthalates can impair Leydig cell distribution and steroidogenesis in the fetal rat in utero, but it is unknown whether similar effects might occur in the human...
  50. ncbi request reprint Safety of trivalent chromium complexes: no evidence for DNA damage in human HaCaT keratinocytes
    Isabelle Hininger
    Laboratoire Nutrition, Vieillissement, Maladies Cardiovasculaires, EA 3746, J Fourier University, Domaine de la Merci, 38700 La Tronche, France
    Free Radic Biol Med 42:1759-65. 2007
    ..These data further support the low toxicity of trivalent Cr complexes used in nutrient supplements...
  51. ncbi request reprint Chromium picolinate and conjugated linoleic acid do not synergistically influence diet- and exercise-induced changes in body composition and health indexes in overweight women
    Megan L Diaz
    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA
    J Nutr Biochem 19:61-8. 2008
    ..The use of a combined CP and CLA supplement for 3 months does not affect diet- and exercise-induced changes in weight and body composition or improve indexes of metabolic and cardiovascular health in young overweight women...
  52. pmc A novel angiogenic role for prostaglandin F2alpha-FP receptor interaction in human endometrial adenocarcinomas
    Kurt J Sales
    Medical Research Council Human Reproductive Sciences Unit, Centre for Reproductive Biology, University of Edinburgh, Edinburgh, United Kingdom
    Cancer Res 65:7707-16. 2005
    ..Finally, we confirmed that PGF2alpha could potentiate angiogenesis in endometrial adenocarcinoma explants by transactivation of the EGFR and induction of VEGF mRNA expression...
  53. pmc Type I gamma phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migration
    Yue Sun
    Department of Pharmacology, School of Medicine and Public Health, University of Wisconsin Madison, Madison, WI 53706, USA
    J Cell Biol 178:297-308. 2007
    ..These interactions in turn define the spatial and temporal generation of PI4,5P(2) and derived messengers required for directional migration...
  54. ncbi request reprint Phenotype of subjects with type 2 diabetes mellitus may determine clinical response to chromium supplementation
    Zhong Q Wang
    Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
    Metabolism 56:1652-5. 2007
    ..4038) (P = .0004). Subject phenotype appears to be very important when assessing the clinical response to Cr because baseline insulin sensitivity was found to account for nearly 40% of the variance in the clinical response to Cr...
  55. ncbi request reprint Impact of obesity on female reproductive health: British Fertility Society, Policy and Practice Guidelines
    Adam H Balen
    Reproductive Medicine and Surgery, Leeds Teaching Hospitals, Leeds, UK
    Hum Fertil (Camb) 10:195-206. 2007
    ..Even a moderate weight loss of 5-10% of body weight can be sufficient to restore fertility and improve metabolic markers...
  56. pmc Conserved and divergent patterns of expression of DAZL, VASA and OCT4 in the germ cells of the human fetal ovary and testis
    Richard A Anderson
    Division of Reproductive and Developmental Sciences, Queen s Medical Research Institute, Edinburgh EH16 4TJ, UK
    BMC Dev Biol 7:136. 2007
    ....
  57. ncbi request reprint Molecular profiling of the human testis reveals stringent pathway-specific regulation of RNA expression following gonadotropin suppression and progestogen treatment
    Rosemary A L Bayne
    MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Queen s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, United Kingdom
    J Androl 29:389-403. 2008
    ....
  58. doi request reprint Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate
    Matthew W Bunce
    Department of Pharmacology, University of Wisconsin, Madison, WI 53706, USA
    J Biol Chem 283:8678-86. 2008
    ....
  59. ncbi request reprint A positive feedback loop that regulates cyclooxygenase-2 expression and prostaglandin F2alpha synthesis via the F-series-prostanoid receptor and extracellular signal-regulated kinase 1/2 signaling pathway
    Henry N Jabbour
    Medical Research Council Human Reproductive Sciences Unit, The Queen s Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland, United Kingdom
    Endocrinology 146:4657-64. 2005
    ..Finally, we have shown that PGF2alpha could potentiate tumorigenesis in endometrial adenocarcinoma explants by inducing the expression of COX-2 mRNA...
  60. ncbi request reprint Chromium supplementation shortens QTc interval duration in patients with type 2 diabetes mellitus
    Matjaz Vrtovec
    Ljubljana University Medical Centre, Ljubljana, Slovenia
    Am Heart J 149:632-6. 2005
    ..We investigated the potential effects of chromium supplementation on QTc interval duration in type 2 diabetic patients...
  61. ncbi request reprint Stereo-specific substrate recognition by phosphatidylinositol phosphate kinases is swapped by changing a single amino acid residue
    Jeannette Kunz
    Department of Pharmacology, University of Wisconsin Medical School, Madison, Wisconsin 53706, USA
    J Biol Chem 277:5611-9. 2002
    ..These results clearly establish the role of the activation loop in determining both signaling specificity and plasma membrane targeting of type I PIP kinases...