J Robert Manak

Summary

Affiliation: Affymetrix Inc
Country: USA

Publications

  1. ncbi request reprint Biological function of unannotated transcription during the early development of Drosophila melanogaster
    J Robert Manak
    Affymetrix, Inc, Santa Clara, California, 95051, USA
    Nat Genet 38:1151-8. 2006
  2. pmc Spatial regulation of microRNA gene expression in the Drosophila embryo
    Frederic Biemar
    Division of Genetics and Development, Department of Molecular Cell Biology, Center for Integrative Genomics, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 102:15907-11. 2005
  3. pmc Comprehensive identification of Drosophila dorsal-ventral patterning genes using a whole-genome tiling array
    Frederic Biemar
    Division of Genetics and Development, Department of Molecular Cell Biology, Center for Integrative Genomics, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 103:12763-8. 2006
  4. pmc Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability
    J Robert Manak
    Department of Pathology, Stanford University School of Medicine, Room L216, 300 Pasteur Drive, Stanford, CA 94305 5324, USA
    Proc Natl Acad Sci U S A 99:7438-43. 2002
  5. ncbi request reprint Role for a Drosophila Myb-containing protein complex in site-specific DNA replication
    Eileen L Beall
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Nature 420:833-7. 2002
  6. ncbi request reprint Loss of Drosophila Myb interrupts the progression of chromosome condensation
    J Robert Manak
    Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5342, USA
    Nat Cell Biol 9:581-7. 2007
  7. pmc Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cells
    Daphne Georlette
    Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California 94720, USA
    Genes Dev 21:2880-96. 2007
  8. pmc Stability and dynamics of polycomb target sites in Drosophila development
    Camilla Kwong
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    PLoS Genet 4:e1000178. 2008

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Biological function of unannotated transcription during the early development of Drosophila melanogaster
    J Robert Manak
    Affymetrix, Inc, Santa Clara, California, 95051, USA
    Nat Genet 38:1151-8. 2006
    ..Collectively, these data indicate that at least 85% of the fly genome is transcribed and processed into mature transcripts representing at least 30% of the fly genome...
  2. pmc Spatial regulation of microRNA gene expression in the Drosophila embryo
    Frederic Biemar
    Division of Genetics and Development, Department of Molecular Cell Biology, Center for Integrative Genomics, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 102:15907-11. 2005
    ..These results provide evidence that restricted activities of the 8-miR and miR-1 miRNAs are mediated by classical tissue-specific enhancers...
  3. pmc Comprehensive identification of Drosophila dorsal-ventral patterning genes using a whole-genome tiling array
    Frederic Biemar
    Division of Genetics and Development, Department of Molecular Cell Biology, Center for Integrative Genomics, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 103:12763-8. 2006
    ..We discuss the potential functions of these recently identified genes and suggest that intronic enhancers are a common feature of the DV gene network...
  4. pmc Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability
    J Robert Manak
    Department of Pathology, Stanford University School of Medicine, Room L216, 300 Pasteur Drive, Stanford, CA 94305 5324, USA
    Proc Natl Acad Sci U S A 99:7438-43. 2002
    ..Together these findings imply that Dm-Myb provides an essential nontranscriptional function during chromosomal replication...
  5. ncbi request reprint Role for a Drosophila Myb-containing protein complex in site-specific DNA replication
    Eileen L Beall
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Nature 420:833-7. 2002
    ..These data provide evidence that specific protein complexes bound to replication enhancer elements work together with the general replication machinery for site-specific origin utilization during replication...
  6. ncbi request reprint Loss of Drosophila Myb interrupts the progression of chromosome condensation
    J Robert Manak
    Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305 5342, USA
    Nat Cell Biol 9:581-7. 2007
    ....
  7. pmc Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cells
    Daphne Georlette
    Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California 94720, USA
    Genes Dev 21:2880-96. 2007
    ....
  8. pmc Stability and dynamics of polycomb target sites in Drosophila development
    Camilla Kwong
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    PLoS Genet 4:e1000178. 2008
    ..Pc/Pho binding does not preclude transcription, but levels of Pc/Pho binding change during development, and loss of Pc/Pho binding can be associated with both stable gene activity and inactivity...