Research Topics
| Marc A SilverSummaryAffiliation: Advocate Christ Medical Center Country: USA Publications
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Publications
Current and emerging issues with B-type natriuretic peptide. Roundtable discussionMarc A Silver
Department of Medicine and the Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, IL 60453, USA
Congest Heart Fail 11:212-4. 2005..The panel gathered to review some of the questions that emerged from the symposium and the questions raised by the attendees. These are of interest and importance to all interested in heart failure and B-type natriuretic peptide...
BNP Consensus Panel 2004: A clinical approach for the diagnostic, prognostic, screening, treatment monitoring, and therapeutic roles of natriuretic peptides in cardiovascular diseasesMarc A Silver
Department of Medicine and Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, IL 60453 2600, USA
Congest Heart Fail 10:1-30. 2004..An expert Consensus Panel with basic, methodological, and clinical expertise was convened to summarize current knowledge in these areas and the findings and consensus statements are contained herein...
Systemic hypertension among women with uterine leiomyomata: potential final common pathways of target end-organ remodelingMarc A Silver
Heart Failure Institute and the Department of Medicine, Advocate Christ Medical Center, Oak Lawn, IL 60453, USA
J Clin Hypertens (Greenwich) 7:664-8. 2005..Thus there appears to be an association between leiomyomata and hypertension, which needs to be explored in future prospective trials...
Evaluation of impedance cardiography as an alternative to pulmonary artery catheterization in critically ill patientsMarc A Silver
Department of Medicine and the Heart Failure Institute, Advocate Christ Hospital and Medical Center, Oak Lawn, IL 60453, USA
Congest Heart Fail 10:17-21. 2004..2%-87.8%). ICG can replace the pulmonary artery catheter in coronary care unit patients, and clinicians utilizing ICG believe it aids medical decision making and improves patient outcomes...
Acute and chronic oral magnesium supplementation: effects on endothelial function, exercise capacity, and quality of life in patients with symptomatic heart failureJohanna C Fuentes
Department of Medicine and Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, IL 60453, USA
Congest Heart Fail 12:9-13. 2006..This study suggests that chronic supplementation with oral magnesium is well tolerated and could improve endothelial function in symptomatic heart failure patients...
Mechanisms and evidence for the role of enhanced external counterpulsation in heart failure managementMarc A Silver
Advocate Christ Medical Center, Suite 319 South, Oak Lawn, IL 60453, USA
Curr Heart Fail Rep 3:25-32. 2006..This paper summarizes some of the mechanisms and outcomes of EECP in HF patients and helps to elucidate the role of EECP in the management of patients with chronic HF...
Statin cardiomyopathy? A potential role for Co-Enzyme Q10 therapy for statin-induced changes in diastolic LV performance: description of a clinical protocolMarc A Silver
Heart Failure Institute, Division of Cardiology, Department of Medicine, Advocate Christ Medical Center and the University of Illinois Christ Cardiovascular Disease Fellowship Program, Oak Lawn, IL 60453, USA
Biofactors 18:125-7. 2003..RESULTS: Statistical analysis will be performed using the paired t test to compare coenzyme levels and echocardiographic indices at baseline and after treatment and after supplementation...
The natriuretic peptide system: kidney and cardiovascular effectsMarc A Silver
Advocate Christ Medical Center, 4440 West 95th Street, Oak Lawn, IL 60453, USA
Curr Opin Nephrol Hypertens 15:14-21. 2006..In addition, synthetic NPs such as nesiritide are available for use in management of patients with acutely decompensated congestive HF...
High incidence of elevated B-type natriuretic peptide levels and risk factors for heart failure in an unselected at-risk population (stage A): implications for heart failure screening programsMarc A Silver
Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, IL 60453, USA
Congest Heart Fail 9:127-32. 2003..Increased public and physician awareness and information are needed to transform screening opportunities into a strategic approach to improve health care and HF prevention...
Heart failure advances... going to the dogsMarc A Silver
Department of Medicine and the Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, IL 60453, USA
Congest Heart Fail 11:215. 2005
Depression and heart failure: an overview of what we know and don't knowMarc A Silver
Clinical Professor of Medicine, University of Illinois, Chicago, IL, USA
Cleve Clin J Med 77:S7-S11. 2010..Nevertheless, early identification of depression in heart failure patients is imperative, as it can facilitate intervention attempts...
Optimizing treatment and outcomes in acute heart failure: beyond initial triageMarc A Silver
Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, IL 60453, USA
Congest Heart Fail 12:137-45. 2006....
Effect of nesiritide versus dobutamine on short-term outcomes in the treatment of patients with acutely decompensated heart failureMarc A Silver
Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, Illinois 60453, USA
J Am Coll Cardiol 39:798-803. 2002....
Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunctionMarc A Silver
Heart Failure Institute, Department of Medicine, Advocate Christ Medical Center, University of Illinois Christ Cardiovascular Disease Fellowship Program, Oak Lawn, Illinois 60453, USA
Am J Cardiol 94:1306-10. 2004..Statin therapy worsened diastolic parameters in most patients; coenzyme Q(10) supplementation in patients with worsening diastolic function with statin therapy improved parameters of diastolic function...
Low incidence of neurologic events during long-term support with the HeartMate XVE left ventricular assist deviceMark S Slaughter
Cardiac Surgery Research and Mechanical Assist Device Program, Advocate Christ Medical Center, Oak Lawn, Illinois 60453, USA
Tex Heart Inst J 35:245-9. 2008..They also suggest that modifications made to the HeartMate LVAD since the REMATCH trial have resulted in fewer complications, and that better patient selection and supportive care have improved outcomes...
Self-management counseling in patients with heart failure: the heart failure adherence and retention randomized behavioral trialLynda H Powell
Department of Preventive Medicine, Rush University Medical Center, 1700 W Van Buren St, Chicago, IL 60612, USA
JAMA 304:1331-8. 2010..Motivating patients with heart failure to adhere to medical advice has not translated into clinical benefit, but past trials have had methodological limitations...
Improvement in early oxygen uptake kinetics with left ventricular assist device supportChad M Feldman
Internal Medicine, Advocate Christ Medical Center, Oak Lawn, Illinois, USA
ASAIO J 54:406-11. 2008..7 seconds to 35.8 +/- 13.3 seconds (p = 0.046) with LVAD support. Improved oxygen kinetics suggests improved peripheral utilization of oxygen, and may offer an additional clinical parameter to predict the likelihood of sustained recovery...
Destination therapy: safety and feasibility of national and international travelLaura A Coyle
Mechanical Assist Device Program, Advocate Christ Medical Center, Oak Lawn, Illinois, USA
ASAIO J 54:172-6. 2008..All patients returned home safely for routine follow-up. Long-distance travel is possible for DT patients. Anticipating potential problems and careful planning is necessary for safe national and international travel...
Treating heart failure with enhanced external counterpulsation (EECP): design of the Prospective Evaluation of EECP in Heart Failure (PEECH) trialArthur M Feldman
Department of Medicine, Jefferson Medical College, 1025 Walnut Street, Philadelphia, PA 19607, USA
J Card Fail 11:240-5. 2005....
Enhanced external counterpulsation: bringing the concept of the intraaortic balloon pump to the outpatient settingHelen Lonergan-Thomas
Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, Illinois 60453, USA
Dimens Crit Care Nurs 23:119-21. 2004..Enhanced external counterpulsation can now be used in patients with congestive heart failure. As our population ages, we will see more patients with this challenging diagnosis. The authors discuss this exciting treatment...
Utilization of acoustic signatures to identify HeartMate XVE device end-of-lifeMark S Slaughter
Mechanical Assist Device Program, Advocate Christ Medical Center, Oak Lawn, Illinois 60453, USA
J Heart Lung Transplant 26:579-83. 2007..In this study we assess a non-invasive technique using acoustic signals generated from the HeartMate XVE LVAD to potentially identify impending device end-of-life issues...
Enhanced external counterpulsation improves exercise tolerance in patients with chronic heart failureArthur M Feldman
Department of Medicine, Jefferson Medical College, Philadelphia, Pennsylvania, USA
J Am Coll Cardiol 48:1198-205. 2006....
Home discharge experience with the Thoratec TLC-II portable driverMark S Slaughter
Mechanical Assist Device Program, Advocate Christ Medical Center, Oak Lawn, IL 60453, USA
ASAIO J 53:132-5. 2007..There were no readmissions for device malfunction, emergency battery utilization or back-up unit use. These results demonstrate that the Thoratec TLC-II portable driver is safe, reliable, and can be effectively managed at home...
Optimizing treatment of chronic decompensated heart failure in the outpatient settingMarc A Silver
Department of Medicine, Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, Illinois, USA
Rev Cardiovasc Med 5:S28-36. 2004..In other patients, nonpharmacologic approaches used in combination with drug therapy may help improve functional status and reduce mortality...
Efficacy of nonsteroidal anti-inflammatory medications for prevention of atrial fibrillation following coronary artery bypass graft surgeryKiran K Cheruku
Advocate Christ Medical Center, Oak Lawn, IL 60453-2600, USA
Prev Cardiol 7:13-8. 2004..8%) in the ibuprofen group (p<0.017). Nonsteroidal anti-inflammatory medications were relatively safe and effective in significantly reducing the incidence of atrial fibrillation after coronary artery bypass graft surgery...
Left ventricular assist device weaning: hemodynamic response and relationship to stroke volume and rate reduction protocolsMark S Slaughter
Mechanical Assist Device Program, Advocate Christ Medical Center, Oak Lawn, IL 60453, USA
ASAIO J 52:228-33. 2006..The long-term effects of steady-state and transient LV mechanical reloading on myocardial structure and function toward achieving sustained myocardial recovery warrant further investigation...
Impact of body mass index on outcomes of enhanced external counterpulsation therapyPeter A McCullough
Division of Cardiology, Department of Medicine, Nutrition and Preventive Medicine, William Beaumont Hospital, Royal Oak, MI 48073, USA
Am Heart J 151:139. 2006..We evaluated the association of baseline body mass index (BMI) on the outcomes of enhanced external counterpulsation (EECP) therapy for chronic stable angina...
Management of aortic insufficiency with continuous flow left ventricular assist devices: bioprosthetic valve replacementChad M Feldman
Advocate Christ Medical Center, Mechanical Assist Device Program, Oak Lawn, Illinois 60453, USA
J Heart Lung Transplant 25:1410-2. 2006..We report on two patients with bioprosthetic aortic valve replacement for aortic insufficiency at the time of HeartMate II LVAD insertion...
Increasing self-management skills in heart failure patients: a pilot studyKristin J Flynn
Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612, USA
Congest Heart Fail 11:297-302. 2005..001) and in several psychosocial outcomes. The success of this pilot study suggests the need for a randomized clinical trial to test the efficacy of group-based self-management training on medical outcomes...
Current and potential applications of left ventricular assist devicesPamela Cianci
Advocate Christ Medical Center, Oak Lawn, Illinois, USA
J Cardiovasc Nurs 18:17-22. 2003..As VAD science advances, nurses will needs to understand its practice implications...
Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trialMichael S Cuffe
Northwestern University Medical School, Division of Cardiology, 201 E Huron St, Galter 10 240, Chicago, IL 60611, USA
JAMA 287:1541-7. 2002..Although intravenous inotropic therapy usually produces beneficial hemodynamic effects and is labeled for use in the care of such patients, the effect of such therapy on intermediate-term clinical outcomes is uncertain...
Management of anemia in heart failureThomas D Stamos
Department of Medicine, Section of Cardiology, University of Illinois at Chicago, Chicago, Illinois, USA
Curr Opin Cardiol 25:148-54. 2010..Anemia would appear to be a reasonable treatment target for patients with heart failure. The review will discuss the potential causes of anemia in heart failure patients and give an up-to-date overview of treatment trials...
Post-acute care: the role of natriuretic peptidesAlan Maisel
San Diego VA Medical Hospital and University of California San Diego, CA 92161, USA
Congest Heart Fail 18:S14-6. 2012....
Symptomatic calcific constrictive pericarditis presenting years after presumed resolved inflammatory heart diseaseTanyanan Tanawuttiwat
Heart Failure Institute, Department of Medicine, Advocate Christ Medical Center University of Illinois at Chicago, USA
Am Heart Hosp J 8:E130-2. 2010..In conclusion, close monitoring and careful evaluation of patients with presumed inflammatory heart disease is warranted because of the potential for late-occurring chronic constrictive sequelae...
Heat therapy in the management of heart failureAdrianna A Weber
Department of Medicine, Heart Failure Institute, University of Illinois at Chicago, Oak Lawn, IL 60453, USA
Congest Heart Fail 13:81-3. 2007..Hopefully future studies will continue to explore heat therapy as adjunctive care for heart failure patients...
Nuggets, pearls, and vignettes of master heart failure clinicians. Part 4--treatmentCarl V Leier
Division of Cardiology, Heart-Lung Research Institute, The Ohio State University Medical Center, Columbus, OH 43210, USA
Congest Heart Fail 8:98-124. 2002
Utility of impedance cardiography for the identification of short-term risk of clinical decompensation in stable patients with chronic heart failureMilton Packer
University of Texas Southwestern Medical Center, Dallas, Texas 75390 8822, USA
J Am Coll Cardiol 47:2245-52. 2006..This study sought to assess the potential utility of impedance cardiography (ICG) in predicting clinical deterioration in ambulatory patients with heart failure (HF)...
Safety and feasibility of using serial infusions of nesiritide for heart failure in an outpatient setting (from the FUSION I trial)Clyde W Yancy
University of Texas Southwestern Medical Center, Dallas, Texas, USA
Am J Cardiol 94:595-601. 2004..Additional studies are needed to determine the effect of outpatient serial infusions of nesiritide on rates of morbidity and mortality in advanced heart failure...
Beyond the four quadrants: the critical and emerging role of impedance cardiography in heart failureJohn E Strobeck
Congest Heart Fail 10:1-6. 2004
Nesiritide in acute heart failureAndrew J Burger
Lancet 362:998; author reply 998-9. 2003
Decompensated heart failure: is there a role for the outpatient use of nesiritide?Clyde W Yancy
University of Texas Southwestern Medical Center, Department of Internal Medicine Cardiology Division, CS7 102, 5323 Harry Hines Boulevard, Dallas, TX 75235, USA
Congest Heart Fail 10:230-6. 2004..Such an approach, once validated, should be integrated into an evidence-based HF disease management program...
New approaches to hemodynamic measurement cool devices but a shaky infrastructureMarc A Silver
J Am Coll Cardiol 50:2383-4. 2007
Outcomes of left ventricular assist device implantation as destination therapy in the post-REMATCH era: implications for patient selectionKatherine Lietz
Cardiovascular Division, University of Minnesota, Minneapolis, USA
Circulation 116:497-505. 2007..In the present study, we describe outcomes of DT in the post-REMATCH era in the United States...
Nesiritide added to standard care favorably reduces systolic blood pressure compared with standard care alone in patients with acute decompensated heart failureW Franklin Peacock
Department of Emergency Medicine, The Cleveland Clinic Foundation, OH 44195, USA
Am J Emerg Med 23:327-31. 2005..03]). Both treatment groups had similar incidences of symptomatic and asymptomatic hypotension. These data demonstrate that early administration of nesiritide in the emergency department is a safe and effective treatment of heart failure...
The Second Follow-up Serial Infusions of Nesiritide (FUSION II) trial for advanced heart failure: study rationale and designClyde W Yancy
Baylor University Medical Center, Heart and Vascular Institute, Dallas, TX 75246, USA
Am Heart J 153:478-84. 2007..Within a prespecified subset of high-risk patients, a potential signal of benefit on a combined end point of mortality and cardiovascular hospitalization was identified...
Enhanced external counterpulsation improves exercise duration and peak oxygen consumption in older patients with heart failure: a subgroup analysis of the PEECH trialCharles W Abbottsmith
The Ohio Heart and Vascular Center, Cincinnati, OH 45219, USA
Congest Heart Fail 12:307-11. 2006..017). The authors conclude that an older subgroup of PEECH subjects confirms the beneficial effect of EECP in patients with chronic, stable, mild-to-moderate heart failure...
Angina patients with diastolic versus systolic heart failure demonstrate comparable immediate and one-year benefit from enhanced external counterpulsationWilliam E Lawson
SUNY Stony Brook, Stony Brook, NY 11740, USA
J Card Fail 11:61-6. 2005..MACE at 1 year was also comparable (24.4 versus 23.8%). CONCLUSIONS: The benefits of EECP in heart failure patients were similar regardless of diastolic or systolic dysfunction. The improvement was sustained at 1 year with similar MACE...
Using homeostatic peptides in decompensated heart failure a reasonable paradigm but a flawed practice?Marc A Silver
J Am Coll Cardiol 50:1841-3. 2007
ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: executive summarySharon A Hunt
American College of Cardiology/American Heart Association Task Force on Practice Guidelines
J Heart Lung Transplant 21:189-203. 2002
Impact of nonfatal myocardial infarction on outcomes in patients with advanced heart failure and the effect of bucindolol therapyCHRISTOPHER M O'CONNOR
Duke University Medical Center, Durham, North Carolina, USA
Am J Cardiol 95:558-64. 2005..Beta-blocker therapy with bucindolol appears to attenuate the risk of nonfatal MI in this population...
Thermal therapy: a viable adjunct in the treatment of heart failure?Tofy Mussivand
University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Congest Heart Fail 14:180-6. 2008..The clinical evidence highlights repeatable and compelling data showing that thermal therapy may provide an important and viable adjunct in the treatment of heart failure...
