Research Topics
| J U AdelmanSummaryCountry: USA Publications
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Publications
Analysis of safety and tolerability data obtained from over 1,500 patients receiving topiramate for migraine prevention in controlled trialsJames Adelman
Headache Wellness Center, Greensboro, North Carolina 27405, USA
Pain Med 9:175-85. 2008....
Meta-analysis of oral triptan therapy for migraine: number needed to treat and relative cost to achieve relief within 2 hoursJames U Adelman
Headache Wellness Center, 301 E Wendover Ave, Greensboro, NC 27401, USA
J Manag Care Pharm 9:45-52. 2003..To determine the cost-effectiveness of the 5-HT1B/1D agonists, or triptans, in the acute treatment of migraine...
Comparative aspects of triptans in treating migraineJ U Adelman
Department of Neurology, University of North Carolina, Chapel Hill, North Carolina, USA
Clin Cornerstone 4:53-64. 2001..The many triptans available offer the opportunity to individualize migraine treatment, depending on the patient's attack characteristics, tolerance, and preferences...
Cost-effectiveness of antiepileptic drugs in migraine prophylaxisJames U Adelman
Headache Wellness Center, Greensboro, North Carolina, 27401, USA
Headache 42:978-83. 2002..To analyze the cost-effectiveness of antiepileptics in migraine prophylaxis...
Comparison of rizatriptan and other triptans on stringent measures of efficacyJ U Adelman
Headache Wellness Center, Greensboro, NC 27401, USA
Neurology 57:1377-83. 2001..To compare the efficacy of oral rizatriptan 10 mg with oral doses of sumatriptan, naratriptan, and zolmitriptan on stringent outcome measures...
Current options for the prevention and treatment of migraineJ U Adelman
Headache Wellness Center Greensboro, North Carolina 27401, USA
Clin Ther 23:772-88; discussion 771. 2001..Migraine is a common condition affecting approximately 18% of women and 6% of men in the United States. The goals of managing migraine are 2-fold: to prevent attacks from occurring and to effectively and rapidly end them when they do occur...
Rizatriptan tablet versus wafer: patient preferenceJ U Adelman
Headache Wellness Center, Greensboro, NC 27403, USA
Headache 40:371-2. 2000..Of the 367 patients studied, 188 selected the oral disintegrating tablet, while 179 preferred the conventional tablet. Although individual patients had strong preferences for one preparation over the other, no group preference was found...
Oral narcotic protocol to reduce narcotic injections in refractory migraine patientsR L Von Seggern
Adelman Headache Center, Greensboro, NC 27403, USA
Headache 37:341-5. 1997..This was offset by an oral narcotic protocol medication cost of only $392. This treatment method has been well accepted by patients and has proven to be a safe and cost-effective approach to treating refractory migraine patients...
Cost considerations in headache treatment. Part 2: Acute migraine treatmentR L Von Seggern
Adelman Headache Center, Greensboro, NC 27403, USA
Headache 36:493-502. 1996..Sophisticated comparative studies are needed to evaluate, not only the direct costs of medications, but all costs of treatment of an acute migraine attack, as well as indirect costs to the patient, family, and society...
Cost considerations in headache treatment. Part 1: Prophylactic migraine treatmentJ U Adelman
Adelman Headache Center, Greensboro, NC 27403, USA
Headache 35:479-87. 1995..62/month). Better information is needed concerning effectiveness and optimal dosing of some older low-cost medications in the preventive treatment of migraine...
Almotriptan versus sumatriptan in migraine treatment: direct medical costs of managing adverse chest symptomsLisa K Mannix
Headache Wellness Center, Greensboro, North Carolina, USA
Am J Manag Care 8:S94-101. 2002..64 for patients treated with sumatriptan, a difference of $1.42 per patient. CONCLUSION: Relative to sumatriptan, treatment with almotriptan is likely to reduce patient care costs associated with chest symptom adverse events...
Venlafaxine extended release (XR) for the prophylaxis of migraine and tension-type headache: A retrospective study in a clinical settingL C Adelman
Headache Wellness Center, Greensboro, NC 27403, USA
Headache 40:572-80. 2000..We recommend a double-blind, placebo-controlled study to further assess the role of extended-release venlafaxine in headache prevention...
Efficacy of topiramate in migraine prophylaxis: a retrospective chart analysisRandal L Von Seggern
Headache Wellness Center, Greensboro, North Carolina 27401, USA
Headache 42:804-9. 2002..In particular, topiramate may offer relief to patients with moderate/severe migraines who do not respond to other treatments...
The effect of early intervention with sumatriptan tablets on migraine-associated productivity lossW Jacqueline Kwong
GlaxoSmithKline, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
J Occup Environ Med 47:1167-73. 2005..This analysis examined productivity loss as a result of migraine after treatment with sumatriptan tablets and patients' usual non-triptan therapy when pain was mild (early intervention) versus when pain was moderate/severe...
Cost considerations of acute migraine treatmentJames U Adelman
Headache Wellness Center, Greensboro, NC 27401, USA
Headache 44:271-85. 2004..89 dollars. CONCLUSIONS: Practitioners can optimize the use of health care dollars without compromising quality of care through awareness of cost-saving treatment strategies, as well as price variations among medications...
A randomized trial of frovatriptan for the intermittent prevention of menstrual migraineJames U Adelman
Neurology 64:931; author reply 931. 2005
Meta-analysis methodology: the battle continuesJonathan Belsey
Headache 43:1119-21; author reply 1121. 2003
Sumatriptan-naproxen for acute treatment of migraine: a randomized trialJan Lewis Brandes
Nashville Neuroscience Group, Nashville, Tenn 37203, USA
JAMA 297:1443-54. 2007..Multiple pathogenic mechanisms may be involved in generating the migraine symptom complex, and multimechanism-targeted therapy may confer advantages over monotherapy...
Does migraine preventive medication actually reduce resource utilization?James U Adelman
Headache 43:1116-8; author reply 1118. 2003
