Michel WarnySummaryAffiliation: Acambis Inc Country: USA Publications
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Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and EuropeMichel Warny
Acambis Inc, Cambridge, MA, USA
Lancet 366:1079-84. 2005..We characterised the dominant strain of this epidemic to determine whether it produces higher amounts of toxins A and B than those produced by non-epidemic strains...
Active and passive immunization against Clostridium difficile diarrhea and colitisPaul J Giannasca
Acambis Inc, 38 Sidney Street, Cambridge, MA 02139, USA
Vaccine 22:848-56. 2004..An active vaccine and various immunotherapeutic strategies under evaluation may prove to be effective against severe or relapsing C. difficile infection...
Clostridium difficile vaccine and serum immunoglobulin G antibody response to toxin ASamer Aboudola
Gastroenterology Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
Infect Immun 71:1608-10. 2003..These findings support the feasibility of using a vaccine to protect high-risk individuals against C. difficile-associated diarrhea and colitis...
Clostridium difficile toxoid vaccine in recurrent C. difficile-associated diarrheaStavros Sougioultzis
Gastroenterology Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, 02215, USA
Gastroenterology 128:764-70. 2005..The results of this study support the feasibility of active vaccination against C difficile and its toxins in high-risk individuals but must be validated in larger, randomized, controlled trials...
