B B Spear

Summary

Affiliation: Abbott Laboratories
Country: USA

Publications

  1. ncbi request reprint Clinical application of pharmacogenetics
    B B Spear
    Abbott Laboratories, D424 Bldg AP6A, 100 Abbott Park Road, North Chicago, IL 60064 6008, USA
    Trends Mol Med 7:201-4. 2001
  2. ncbi request reprint Pharmacogenetics and antiepileptic drugs
    B B Spear
    Pharmacogenetics Department, Abbott Laboratories, Abbott Park, Illinois 60064 6008, USA
    Epilepsia 42:31-4. 2001
  3. ncbi request reprint Variants in Apaf-1 segregating with major depression promote apoptosome function
    J Harlan
    Advanced Technologies, Abbott Laboratories, 100 Abbott Park Road R424 AP10, Abbott Park, IL 60064, USA
    Mol Psychiatry 11:76-85. 2006

Collaborators

  • A Hahn
  • M Gopalakrishnan
  • Y Chen
  • J Harlan
  • J P Sullivan
  • C D Neff
  • S Dorwin
  • D A Katz
  • V Abkevich
  • U Ladror
  • M Lake
  • M H Skolnick
  • K Walter
  • A Beck
  • D A Egan
  • J M Roch
  • J Potter
  • R W Johnson
  • J Severin
  • C Davenport
  • T F Holzman
  • R Mueller
  • P Metzger
  • T Olsen
  • D Shattuck
  • D N Halbert
  • E Gubbins
  • K Voelp

Detail Information

Publications3

  1. ncbi request reprint Clinical application of pharmacogenetics
    B B Spear
    Abbott Laboratories, D424 Bldg AP6A, 100 Abbott Park Road, North Chicago, IL 60064 6008, USA
    Trends Mol Med 7:201-4. 2001
    ..By predicting the drug response of an individual, it will be possible to increase the success of therapies and reduce the incidence of adverse side effects...
  2. ncbi request reprint Pharmacogenetics and antiepileptic drugs
    B B Spear
    Pharmacogenetics Department, Abbott Laboratories, Abbott Park, Illinois 60064 6008, USA
    Epilepsia 42:31-4. 2001
    ..The combination of clinical investigations, genomics, and emerging testing methodologies should lead to new tools for the effective management of epilepsy...
  3. ncbi request reprint Variants in Apaf-1 segregating with major depression promote apoptosome function
    J Harlan
    Advanced Technologies, Abbott Laboratories, 100 Abbott Park Road R424 AP10, Abbott Park, IL 60064, USA
    Mol Psychiatry 11:76-85. 2006
    ..The depression-associated alleles thus have a common phenotype that is distinct from that of non-associated variants. This result suggests an etiologic role for enhanced apoptosis in major depression...