- Clinical application of pharmacogeneticsB B Spear
Abbott Laboratories, D424 Bldg AP6A, 100 Abbott Park Road, North Chicago, IL 60064 6008, USA
Trends Mol Med 7:201-4. 2001..By predicting the drug response of an individual, it will be possible to increase the success of therapies and reduce the incidence of adverse side effects...
- Pharmacogenetics and antiepileptic drugsB B Spear
Pharmacogenetics Department, Abbott Laboratories, Abbott Park, Illinois 60064 6008, USA
Epilepsia 42:31-4. 2001..The combination of clinical investigations, genomics, and emerging testing methodologies should lead to new tools for the effective management of epilepsy...
- Variants in Apaf-1 segregating with major depression promote apoptosome functionJ Harlan
Advanced Technologies, Abbott Laboratories, 100 Abbott Park Road R424 AP10, Abbott Park, IL 60064, USA
Mol Psychiatry 11:76-85. 2006..The depression-associated alleles thus have a common phenotype that is distinct from that of non-associated variants. This result suggests an etiologic role for enhanced apoptosis in major depression...