DANIEL A LLANO

Summary

Affiliation: Abbott Laboratories
Country: USA

Publications

  1. ncbi Derivation of a new ADAS-cog composite using tree-based multivariate analysis: prediction of conversion from mild cognitive impairment to Alzheimer disease
    DANIEL A LLANO
    Abbott Laboratories, Abbott Park, IL, USA
    Alzheimer Dis Assoc Disord 25:73-84. 2011
  2. ncbi Magnetic resonance imaging detection and time course of cerebral microhemorrhages during passive immunotherapy in living amyloid precursor protein transgenic mice
    Feng Luo
    Translational Imaging and Biochemical Biomarkers, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, Illinois 60064, USA
    J Pharmacol Exp Ther 335:580-8. 2010
  3. ncbi Pharmacokinetic modeling and [¹²³]5-IA-85380 single photon emission computed tomography imaging in baboons: optimization of dosing regimen for ABT-089
    Chih Liang Chin
    Advanced Technology, Global Pharmaceutical Research and Development, Abbott Park, IL 60064, USA
    J Pharmacol Exp Ther 336:716-23. 2011

Collaborators

  • Viswanath Devanarayan
  • Chih Liang Chin
  • Gerard B Fox
  • Mark Day
  • Feng Luo
  • Michael W Decker
  • Gilles Tamagnan
  • Olivier Barret
  • Jeffrey Batis
  • Andrei O Koren
  • Kennan C Marsh
  • Robert A Carr
  • John P Seibyl
  • Hongyu Xu
  • Nathan R Rustay
  • Terese Seifert
  • Ulrich Ebert
  • Heinz Hillen
  • Beate Roesner
  • Bryan F Cox
  • Vincent Hradil
  • Jean M Severin

Detail Information

Publications3

  1. ncbi Derivation of a new ADAS-cog composite using tree-based multivariate analysis: prediction of conversion from mild cognitive impairment to Alzheimer disease
    DANIEL A LLANO
    Abbott Laboratories, Abbott Park, IL, USA
    Alzheimer Dis Assoc Disord 25:73-84. 2011
    ..These suggest that a modified subscore weighting scheme applied to the 13-item ADAS-cog is comparable to imaging or CSF markers in prediction of conversion from MCI to AD at 12 months...
  2. ncbi Magnetic resonance imaging detection and time course of cerebral microhemorrhages during passive immunotherapy in living amyloid precursor protein transgenic mice
    Feng Luo
    Translational Imaging and Biochemical Biomarkers, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, Illinois 60064, USA
    J Pharmacol Exp Ther 335:580-8. 2010
    ..A highly selective antibody for soluble Aβ is needed to address the question of whether antibodies that do not bind to deposited Aβ have microhemorrhage liability...
  3. ncbi Pharmacokinetic modeling and [¹²³]5-IA-85380 single photon emission computed tomography imaging in baboons: optimization of dosing regimen for ABT-089
    Chih Liang Chin
    Advanced Technology, Global Pharmaceutical Research and Development, Abbott Park, IL 60064, USA
    J Pharmacol Exp Ther 336:716-23. 2011
    ..Our data demonstrate the feasibility of predicting plasma exposures using a two-compartment pharmacokinetic model and its potential for optimizing dosing regimens...