Robert Eichler

Summary

Affiliation: Abbott Laboratories
Country: USA

Publications

  1. ncbi request reprint Evaluation of the new ARCHITECT Rubella IgM assay
    Robert Eichler
    Abbott GmbH and Co KG, Max Planck Ring 2, 65205 Wiesbaden Delkenheim, Germany
    J Clin Virol 39:182-7. 2007
  2. pmc The role of single N-glycans in proteolytic processing and cell surface transport of the Lassa virus glycoprotein GP-C
    Robert Eichler
    Institut für Virologie der Philipps Universität Marburg, Hans Meerwein Str, 3, 35037 Marburg, Germany
    Virol J 3:41. 2006
  3. pmc The role of myristoylation in the membrane association of the Lassa virus matrix protein Z
    Thomas Strecker
    Institut für Virologie der Philipps Universität Marburg, Hans Meerwein Str, 3, 35037 Marburg, Germany
    Virol J 3:93. 2006
  4. ncbi request reprint Characterization of the Lassa virus matrix protein Z: electron microscopic study of virus-like particles and interaction with the nucleoprotein (NP)
    Robert Eichler
    Institut für Virologie der Philipps Universität Marburg, Robert Koch Strasse 17, D 35037 Marburg, Germany
    Virus Res 100:249-55. 2004
  5. ncbi request reprint Signal peptide of Lassa virus glycoprotein GP-C exhibits an unusual length
    Robert Eichler
    Institut für Virologie der Philipps Universität Marburg, Robert Koch Strasse 17, D 35037 Marburg, Germany
    FEBS Lett 538:203-6. 2003
  6. pmc Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor
    Robert Eichler
    Institut für Virologie der Philipps Universität Marburg, Robert Koch Strasse 17, D 35037 Marburg, Germany
    EMBO Rep 4:1084-8. 2003
  7. ncbi request reprint Lassa virus glycoprotein signal peptide displays a novel topology with an extended endoplasmic reticulum luminal region
    Robert Eichler
    Institut für Virologie der Philipps Universität Marburg, Robert Koch Strasse 17, D 35037 Marburg, Germany
    J Biol Chem 279:12293-9. 2004
  8. pmc Lassa virus Z protein is a matrix protein and sufficient for the release of virus-like particles [corrected]
    Thomas Strecker
    Institut für Virologie der Philipps Universität Marburg, D 35037 Marburg, Germany
    J Virol 77:10700-5. 2003

Detail Information

Publications8

  1. ncbi request reprint Evaluation of the new ARCHITECT Rubella IgM assay
    Robert Eichler
    Abbott GmbH and Co KG, Max Planck Ring 2, 65205 Wiesbaden Delkenheim, Germany
    J Clin Virol 39:182-7. 2007
    ..Rubella serology of a primary rubella infection is mainly determined by diagnostic confirmation of levels of specific IgM...
  2. pmc The role of single N-glycans in proteolytic processing and cell surface transport of the Lassa virus glycoprotein GP-C
    Robert Eichler
    Institut für Virologie der Philipps Universität Marburg, Hans Meerwein Str, 3, 35037 Marburg, Germany
    Virol J 3:41. 2006
    ..The findings indicate that N-glycans are needed for correct conformation of GP-C in order to be cleaved by SKI-1/S1P...
  3. pmc The role of myristoylation in the membrane association of the Lassa virus matrix protein Z
    Thomas Strecker
    Institut für Virologie der Philipps Universität Marburg, Hans Meerwein Str, 3, 35037 Marburg, Germany
    Virol J 3:93. 2006
    ..Our data indicate that myristoylation of Z is critical for its binding ability to lipid membranes and thus, for effective virus budding...
  4. ncbi request reprint Characterization of the Lassa virus matrix protein Z: electron microscopic study of virus-like particles and interaction with the nucleoprotein (NP)
    Robert Eichler
    Institut für Virologie der Philipps Universität Marburg, Robert Koch Strasse 17, D 35037 Marburg, Germany
    Virus Res 100:249-55. 2004
    ..We assume that Z recruits NP to cellular membranes where virus assembly takes place. We conclude from our data that Lassa virus Z protein plays an essential role in Lassa virus maturation...
  5. ncbi request reprint Signal peptide of Lassa virus glycoprotein GP-C exhibits an unusual length
    Robert Eichler
    Institut für Virologie der Philipps Universität Marburg, Robert Koch Strasse 17, D 35037 Marburg, Germany
    FEBS Lett 538:203-6. 2003
    ..Interestingly, GP-C mutants with a non-cleavable signal peptide were not further processed by SKI-1/S1P. This observation suggests that the signal peptide cleavage is necessary for GP-C maturation and hence for Lassa virus replication...
  6. pmc Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor
    Robert Eichler
    Institut für Virologie der Philipps Universität Marburg, Robert Koch Strasse 17, D 35037 Marburg, Germany
    EMBO Rep 4:1084-8. 2003
    ..To our knowledge, this is the first report on a signal peptide that is essential for proteolytic processing of a secretory pathway protein...
  7. ncbi request reprint Lassa virus glycoprotein signal peptide displays a novel topology with an extended endoplasmic reticulum luminal region
    Robert Eichler
    Institut für Virologie der Philipps Universität Marburg, Robert Koch Strasse 17, D 35037 Marburg, Germany
    J Biol Chem 279:12293-9. 2004
    ....
  8. pmc Lassa virus Z protein is a matrix protein and sufficient for the release of virus-like particles [corrected]
    Thomas Strecker
    Institut für Virologie der Philipps Universität Marburg, D 35037 Marburg, Germany
    J Virol 77:10700-5. 2003
    ..contains two late domains, PTAP and PPXY, necessary for the release of virus-like particles. Our data provide evidence that Z is the Lassa virus matrix protein that is the driving force for virus particle release...