Leslie K Diaz

Summary

Affiliation: Abbott Northwestern Hospital
Country: USA

Publications

  1. pmc COX-2 and PPARgamma expression are potential markers of recurrence risk in mammary duct carcinoma in-situ
    Swati Kulkarni
    Lynn Sage Breast Center and Feinberg School of Medicine of Northwestern University, Chicago USA
    BMC Cancer 8:36. 2008
  2. ncbi request reprint Triple negative breast carcinoma and the basal phenotype: from expression profiling to clinical practice
    Leslie K Diaz
    Piper Breast Center, Virginia Piper Cancer Institute, Abbott Northwestern Hospital, Minneapolis, MN 55407, USA
    Adv Anat Pathol 14:419-30. 2007
  3. doi request reprint Clinical, histopathologic, and immunohistochemical features of microglandular adenosis and transition into in situ and invasive carcinoma
    Ibrahim M Khalifeh
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 32:544-52. 2008
  4. ncbi request reprint CD44 expression is associated with increased survival in node-negative invasive breast carcinoma
    Leslie K Diaz
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 11:3309-14. 2005
  5. ncbi request reprint alphaB-crystallin is a novel predictor of resistance to neoadjuvant chemotherapy in breast cancer
    Olga Ivanov
    Department of Surgery, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA
    Breast Cancer Res Treat 111:411-7. 2008
  6. ncbi request reprint Estrogen receptor analysis for breast cancer: current issues and keys to increasing testing accuracy
    Leslie K Diaz
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Adv Anat Pathol 12:10-9. 2005
  7. ncbi request reprint Benign metastasizing leiomyoma: clonality, telomere length and clinicopathologic analysis
    Kurt T Patton
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Mod Pathol 19:130-40. 2006
  8. pmc AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer
    Jose V Moyano
    Cell Death Regulation Laboratory, Department of Medicine, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Clin Invest 116:261-70. 2006
  9. ncbi request reprint A 59-year-old woman with a spindle cell lesion of the breast. Low-grade (fibromatosis-like) spindle cell carcinoma of the breast
    Kristian T Schafernak
    Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Arch Pathol Lab Med 130:e81-3. 2006
  10. ncbi request reprint Assessment of two automated imaging systems in evaluating estrogen receptor status in breast carcinoma
    Sumita Gokhale
    Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Appl Immunohistochem Mol Morphol 15:451-5. 2007

Collaborators

Detail Information

Publications23

  1. pmc COX-2 and PPARgamma expression are potential markers of recurrence risk in mammary duct carcinoma in-situ
    Swati Kulkarni
    Lynn Sage Breast Center and Feinberg School of Medicine of Northwestern University, Chicago USA
    BMC Cancer 8:36. 2008
    ..We performed a case-control study to identify protein markers of local recurrence risk in DCIS...
  2. ncbi request reprint Triple negative breast carcinoma and the basal phenotype: from expression profiling to clinical practice
    Leslie K Diaz
    Piper Breast Center, Virginia Piper Cancer Institute, Abbott Northwestern Hospital, Minneapolis, MN 55407, USA
    Adv Anat Pathol 14:419-30. 2007
    ....
  3. doi request reprint Clinical, histopathologic, and immunohistochemical features of microglandular adenosis and transition into in situ and invasive carcinoma
    Ibrahim M Khalifeh
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 32:544-52. 2008
    ....
  4. ncbi request reprint CD44 expression is associated with increased survival in node-negative invasive breast carcinoma
    Leslie K Diaz
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Clin Cancer Res 11:3309-14. 2005
    ..The purpose of this study was to evaluate the prognostic significance of CD44 isoforms in early-stage, lymph node-negative invasive breast carcinoma...
  5. ncbi request reprint alphaB-crystallin is a novel predictor of resistance to neoadjuvant chemotherapy in breast cancer
    Olga Ivanov
    Department of Surgery, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA
    Breast Cancer Res Treat 111:411-7. 2008
    ..We examined whether alphaB-crystallin expression in breast cancer was associated with a poor response to neoadjuvant (preoperative) chemotherapy...
  6. ncbi request reprint Estrogen receptor analysis for breast cancer: current issues and keys to increasing testing accuracy
    Leslie K Diaz
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Adv Anat Pathol 12:10-9. 2005
    ..We additionally highlight recent biologic, molecular, and gene expression profiling data related to ER in breast cancer...
  7. ncbi request reprint Benign metastasizing leiomyoma: clonality, telomere length and clinicopathologic analysis
    Kurt T Patton
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Mod Pathol 19:130-40. 2006
    ..Our evidence supports the notion that benign metastasizing leiomyoma is clonally derived from benign-appearing uterine leiomyomas...
  8. pmc AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer
    Jose V Moyano
    Cell Death Regulation Laboratory, Department of Medicine, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Clin Invest 116:261-70. 2006
    ..Our data also implicate the MEK/ERK pathway as a potential therapeutic target for these tumors...
  9. ncbi request reprint A 59-year-old woman with a spindle cell lesion of the breast. Low-grade (fibromatosis-like) spindle cell carcinoma of the breast
    Kristian T Schafernak
    Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    Arch Pathol Lab Med 130:e81-3. 2006
  10. ncbi request reprint Assessment of two automated imaging systems in evaluating estrogen receptor status in breast carcinoma
    Sumita Gokhale
    Department of Pathology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Appl Immunohistochem Mol Morphol 15:451-5. 2007
    ..In 4 of these, the percentage of cells staining for ER was low (0% to 20%). Overall, the 2 systems were comparable, and discrepant results were most frequently seen when analyzing tumors with low levels of ER positive cells...
  11. doi request reprint AlphaB-crystallin: a novel marker of invasive basal-like and metaplastic breast carcinomas
    Stephanie M Sitterding
    Department of Pathology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Ann Diagn Pathol 12:33-40. 2008
    ....
  12. ncbi request reprint Cyclin D1 expression in melanocytic lesions of the skin
    James A Ramirez
    Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Ann Diagn Pathol 9:185-8. 2005
    ..The role of cyclin D1 in the development and progression of melanomas is controversial. The goal of this study is to evaluate the role of cyclin D1 in benign and malignant melanocytic lesions of the skin...
  13. ncbi request reprint Predictors of residual disease in repeat excisions for lumpectomies with margins less than 0.1 cm
    Norma Rodriguez
    Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
    Clin Breast Cancer 6:169-72. 2005
    ....
  14. ncbi request reprint Immunohistochemical detection of the beta4 integrin subunit in pancreatic adenocarcinoma
    Brianna Gleason
    Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
    J Histochem Cytochem 53:799-801. 2005
    ..We found that the beta4 integrin subunit protein was overexpressed in the majority of pancreatic carcinoma cases tested, whereas chronic pancreatitis and normal pancreas did not display substantial levels of expression...
  15. ncbi request reprint Effect of time interval on residual disease in breast cancer
    Elizabeth L Wiley
    Lynn Sage Breast Cancer Northwestern Memorial Hospital, Department of Pathology, Northwestern University School of Medicine, Chicago, Illinois, USA
    Am J Surg Pathol 27:194-8. 2003
    ..0043); this decrease was not found associated with ductal carcinoma in situ. These findings suggest that the host response to injury may destroy residual infiltrating carcinoma cells in some margin-positive cases...
  16. ncbi request reprint Histologic localization of sentinel lymph node metastases in breast cancer
    Leslie K Diaz
    Department of Pathology, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Am J Surg Pathol 27:385-9. 2003
    ..This information may be useful in determining the optimal method for evaluating axillary sentinel lymph node specimens from breast cancer patients...
  17. pmc Chromogenic in situ hybridization for alpha6beta4 integrin in breast cancer: correlation with protein expression
    Leslie K Diaz
    Department of Pathology, MD Anderson Cancer Center, Houston, Texas 77030, USA
    J Mol Diagn 6:10-5. 2004
    ....
  18. ncbi request reprint The use of TMA for interlaboratory validation of FISH testing for detection of HER2 gene amplification in breast cancer
    Leslie K Diaz
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    J Histochem Cytochem 52:501-7. 2004
    ..Good concordance was observed between HER2 IHC and in situ hybridization testing. TMA is a robust and effective method for the technical validation of HER2 FISH testing and should be considered for use by quality assessment programs...
  19. ncbi request reprint High-quality HER-2 testing: setting a standard for oncologic biomarker assessment
    Elizabeth L Wiley
    JAMA 291:2019-20. 2004
  20. ncbi request reprint Interobserver agreement for estrogen receptor immunohistochemical analysis in breast cancer: a comparison of manual and computer-assisted scoring methods
    Leslie K Diaz
    Department of Surgical Pathology, Northwestern Memorial Hospital, Chicago, IL, USA
    Ann Diagn Pathol 8:23-7. 2004
    ..Our findings show that interobserver agreement for manual scoring of ER is strong, and that manual or computer-aided scoring techniques are comparable...
  21. pmc A comparison of ductoscopy-guided and conventional surgical excision in women with spontaneous nipple discharge
    Robyn M Moncrief
    Department of Surgery, Feinberg School of Medicine and Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, USA
    Ann Surg 241:575-81. 2005
    ..Ductoscopy has been reported to result in improved localization of intraductal lesions and may avoid surgery in women with endoscopically normal ducts...
  22. ncbi request reprint Beta4 integrin subunit gene expression correlates with tumor size and nuclear grade in early breast cancer
    Leslie K Diaz
    Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Mod Pathol 18:1165-75. 2005
    ....
  23. ncbi request reprint Extensive myxoid change in well-differentiated papillary mesothelioma of the pelvic peritoneum
    Leslie K Diaz
    Department of Pathology, Northwestern Memorial Hospital and Northwestern University Medical School, Chicago, IL, USA
    Ann Diagn Pathol 6:164-7. 2002
    ..It is suggested that mesothelioma with myxoid change should be included with differential diagnoses of myxoid lesions of the peritoneum...