Gustavo J Rodrigo

Summary

Affiliation: Departamento de Emergencia
Country: Uruguay

Publications

  1. ncbi Tiotropium for the treatment of stable chronic obstructive pulmonary disease: a systematic review with meta-analysis
    Gustavo J Rodrigo
    Clinica Respirar, Benito Nardone 2310, Montevideo 11300, Uruguay
    Pulm Pharmacol Ther 20:495-502. 2007
  2. ncbi The role of antileukotriene therapy in seasonal allergic rhinitis: a systematic review of randomized trials
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, and Clinica Respirar, Benito Nardone, Montevideo, Uruguay
    Ann Allergy Asthma Immunol 96:779-86. 2006
  3. ncbi Comparison of inhaled fluticasone with intravenous hydrocortisone in the treatment of adult acute asthma
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Am J Respir Crit Care Med 171:1231-6. 2005
  4. doi Tiotropium and risk for fatal and nonfatal cardiovascular events in patients with chronic obstructive pulmonary disease: systematic review with meta-analysis
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Respir Med 103:1421-9. 2009
  5. doi Predicting response to therapy in acute asthma
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
    Curr Opin Pulm Med 15:35-8. 2009
  6. doi Safety of regular use of long-acting beta agonists as monotherapy or added to inhaled corticosteroids in asthma. A systematic review
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Pulm Pharmacol Ther 22:9-19. 2009
  7. doi Safety of long-acting beta-agonists in stable COPD: a systematic review
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Chest 133:1079-87. 2008
  8. ncbi Rapid effects of inhaled corticosteroids in acute asthma: an evidence-based evaluation
    Gustavo J Rodrigo
    Clinica Respirar, Benito Nardone 2310, Montevideo 11300, Uruguay
    Chest 130:1301-11. 2006
  9. ncbi [Critical analysis of asthma guidelines: are they really evidence-based?]
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Facultad de Medicina, Centro Latinoamericano de Economía Humana del Uruguay CLAEH, Punta del Este, Uruguay
    Arch Bronconeumol 44:81-6. 2008
  10. ncbi Body mass index and response to emergency department treatment in adults with severe asthma exacerbations: a prospective cohort study
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las FF AA, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Chest 132:1513-9. 2007

Detail Information

Publications34

  1. ncbi Tiotropium for the treatment of stable chronic obstructive pulmonary disease: a systematic review with meta-analysis
    Gustavo J Rodrigo
    Clinica Respirar, Benito Nardone 2310, Montevideo 11300, Uruguay
    Pulm Pharmacol Ther 20:495-502. 2007
    ....
  2. ncbi The role of antileukotriene therapy in seasonal allergic rhinitis: a systematic review of randomized trials
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, and Clinica Respirar, Benito Nardone, Montevideo, Uruguay
    Ann Allergy Asthma Immunol 96:779-86. 2006
    ..To evaluate the effect of oral leukotriene receptor antagonists as monotherapy or combined with other drugs in the treatment of seasonal allergic rhinitis...
  3. ncbi Comparison of inhaled fluticasone with intravenous hydrocortisone in the treatment of adult acute asthma
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Am J Respir Crit Care Med 171:1231-6. 2005
    ..Several studies published in the second half of the 1990s have shown a therapeutic early effect of inhaled corticosteroids in acute asthma. However, systemic corticosteroids are considered the standard of care...
  4. doi Tiotropium and risk for fatal and nonfatal cardiovascular events in patients with chronic obstructive pulmonary disease: systematic review with meta-analysis
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Respir Med 103:1421-9. 2009
    ..The purpose of this review was to evaluate the cardiovascular risk of regular use of inhaled tiotropium bromide in patients with COPD of any severity...
  5. doi Predicting response to therapy in acute asthma
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
    Curr Opin Pulm Med 15:35-8. 2009
    ..To analyze the prediction of response of therapy into the context of acute adult asthma assessment in the emergency department (ED) setting...
  6. doi Safety of regular use of long-acting beta agonists as monotherapy or added to inhaled corticosteroids in asthma. A systematic review
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Pulm Pharmacol Ther 22:9-19. 2009
    ..Safety of long-acting beta agonists (LABA) has been questioned and recent evidence suggested a detrimental effect on asthma control as well as an increased risk of death...
  7. doi Safety of long-acting beta-agonists in stable COPD: a systematic review
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Chest 133:1079-87. 2008
    ..The purpose of this review was to assess the safety, and secondarily the efficacy of LABAs...
  8. ncbi Rapid effects of inhaled corticosteroids in acute asthma: an evidence-based evaluation
    Gustavo J Rodrigo
    Clinica Respirar, Benito Nardone 2310, Montevideo 11300, Uruguay
    Chest 130:1301-11. 2006
    ..Current reviews on the use of inhaled corticosteroids (ICS) for acute asthma underestimated their early (minutes) clinical impact and produced conclusions of questionable validity...
  9. ncbi [Critical analysis of asthma guidelines: are they really evidence-based?]
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Facultad de Medicina, Centro Latinoamericano de Economía Humana del Uruguay CLAEH, Punta del Este, Uruguay
    Arch Bronconeumol 44:81-6. 2008
    ..Our main sources of information should therefore be those that apply the best research designs, namely randomized controlled trials or meta-analyses of such trials with consistent results and a low probability of bias...
  10. ncbi Body mass index and response to emergency department treatment in adults with severe asthma exacerbations: a prospective cohort study
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las FF AA, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Chest 132:1513-9. 2007
    ..In acute asthma (AA), overweight/obesity (body mass index [BMI]>or=25 kg/m2) have been related to poorer outcomes and higher risk of complications...
  11. doi Safety and efficacy of combined long-acting beta-agonists and inhaled corticosteroids vs long-acting beta-agonists monotherapy for stable COPD: a systematic review
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo 11600, Uruguay
    Chest 136:1029-38. 2009
    ..However, the evidence has been inconclusive. The aim of this review was to assess the safety and efficacy of LABAs/ICSs compared with LABA monotherapy for patients with moderate-to-very severe COPD...
  12. ncbi Acute asthma in adults: a review
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
    Chest 125:1081-102. 2004
    ..This review describes the epidemiology, costs, pathophysiology, mortality, and management of adult AA in the ED and in the ICU...
  13. doi Formoterol for acute asthma in the emergency department: a systematic review with meta-analysis
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
    Ann Allergy Asthma Immunol 104:247-52. 2010
    ..Although several published studies have suggested that formoterol fumarate could be equivalent to short-acting beta2-agonists (SABAs) for the treatment of asthma exacerbations, its role in acute asthma treatment remains undefined...
  14. ncbi The role of anticholinergics in acute asthma treatment: an evidence-based evaluation
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
    Chest 121:1977-87. 2002
    ..In patients with mild-to-moderate acute asthma, there is no apparent benefit from adding a single dose of an anticholinergic medication...
  15. ncbi Continuous vs intermittent beta-agonists in the treatment of acute adult asthma: a systematic review with meta-analysis
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
    Chest 122:160-5. 2002
    ..These studies have suggested that this therapy is safe, is at least as effective as intermittent nebulization, and may be superior to intermittent nebulization in patients with the most severely impaired pulmonary function...
  16. ncbi Use of helium-oxygen mixtures in the treatment of acute asthma: a systematic review
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
    Chest 123:891-6. 2003
    ..To determine the effect of the addition of heliox to standard medical care on the course of acute asthma...
  17. doi Efficacy and safety of subcutaneous omalizumab vs placebo as add-on therapy to corticosteroids for children and adults with asthma: a systematic review
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Chest 139:28-35. 2011
    ..Omalizumab is a humanized monoclonal anti-IgE for the treatment of severe allergic asthma. Because omalizumab targets an immune system molecule, there has been particular interest in the drug's safety...
  18. ncbi Triple inhaled drug protocol for the treatment of acute severe asthma
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
    Chest 123:1908-15. 2003
    ....
  19. ncbi Inhaled therapy for acute adult asthma
    Gustavo J Rodrigo
    Emergency Department, Hospital Central de las Fuerzas Armadas, Uruguay
    Curr Opin Allergy Clin Immunol 3:169-75. 2003
    ..To evaluate recent developments on emergency department inhalotherapy in non-intubated acute adult asthma patients...
  20. ncbi Inhaled corticosteroids as rescue medication in acute severe asthma
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Avenue 8 de Octubre 3020, Montevideo 11600, Uruguay and Facultad de Medicina Claeh, Prado y Salt Lake, Parada 16, Avenue Roosevelt, Punta del Este, Maldonado, Uruguay
    Expert Rev Clin Immunol 4:723-9. 2008
    ....
  21. ncbi Effects of short-term 28% and 100% oxygen on PaCO2 and peak expiratory flow rate in acute asthma: a randomized trial
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uraguay
    Chest 124:1312-7. 2003
    ..We conducted the first randomized controlled study to assess the effects of short-term 28% and 100% oxygen on PaCO(2) and peak expiratory flow rate (PEFR) in patients with acute severe asthma...
  22. doi Reliability and factor analysis of the Spanish version of the asthma control test
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
    Ann Allergy Asthma Immunol 100:17-22. 2008
    ..The Asthma Control Test (ACT) has been developed to evaluate asthma control and to reflect its nature. A Spanish version of the test has been widely disseminated to physicians, but it has not yet been validated...
  23. doi Comparison of three combined pharmacological approaches with tiotropium monotherapy in stable moderate to severe COPD: a systematic review
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11300, Uruguay
    Pulm Pharmacol Ther 25:40-7. 2012
    ..Guidelines recommend the use of inhaled long-acting bronchodilators, inhaled corticosteroids (ICS) and their combinations for maintenance treatment of moderate to severe COPD. However, there are limited data supporting combination therapy...
  24. doi Daily vs. intermittent inhaled corticosteroids for recurrent wheezing and mild persistent asthma: a systematic review with meta-analysis
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11300, Uruguay
    Respir Med 107:1133-40. 2013
    ..This systematic revue compares the efficacy of daily vs. intermittent ICS among preschoolers, children and adults with persistent wheezing and mild to moderate stable persistent asthma...
  25. ncbi There are no excuses for not performing spirometry in acute asthmatics in the emergency department setting
    Gustavo J Rodrigo
    Chest 131:1615. 2007
  26. ncbi Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis
    Anahí Yánez
    Servicio de alergia e inmunologia clinica, Hospital Aeronautico Central, Buenos Aires, Argentina
    Ann Allergy Asthma Immunol 89:479-84. 2002
    ..We performed a systematic review of randomized, controlled trials to determine whether intranasal corticosteroids offered an advantage over topical antihistamines in the treatment of allergic rhinitis...
  27. ncbi IV magnesium in the treatment of acute severe asthma?
    Gustavo J Rodrigo
    Chest 123:1314-5; author reply 1315-6. 2003
  28. ncbi [Cost effectiveness of the application of inhaled ipratropium bromide in the treatment of adult patients with acute asthma in Uruguay]
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Av 8 de octubre 3020, Montevideo 11600, Uruguay
    Rev Alerg Mex 50:103-7. 2003
    ..However, there is a scarce evidence demonstrating that this therapeutic intervention in cost-effective...
  29. ncbi Intravenous montelukast in acute asthma
    Gustavo J Rodrigo
    Am J Respir Crit Care Med 169:130-1; author reply 131. 2004
  30. ncbi beta-agonists through metered-dose inhaler with valved holding chamber versus nebulizer for acute exacerbation of wheezing or asthma in children under 5 years of age: a systematic review with meta-analysis
    Jose A Castro-Rodriguez
    Pediatric Pulmonary Section, Department of Pediatrics, School of Medicine, University of Chile, Santiago, Chile
    J Pediatr 145:172-7. 2004
    ..To compare the efficacy of beta-agonists given by metered-dose inhaler with a valved holding chamber (MDI+VHC) or nebulizer in children under 5 years of age with acute exacerbations of wheezing or asthma in the emergency department setting...
  31. ncbi Delivery of beta-agonists in the emergency department setting: metered-dose inhalers or nebulizers?
    Gustavo J Rodrigo
    Chest 128:1890. 2005
  32. ncbi Comparison between nebulized adrenaline and beta2 agonists for the treatment of acute asthma. A meta-analysis of randomized trials
    Gustavo J Rodrigo
    Departamento de Emergencia, Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay
    Am J Emerg Med 24:217-22. 2006
    ..To evaluate the efficacy of aerosolized adrenaline compared to inhaled beta(2) agonists in the treatment of acute asthma in the emergency setting...
  33. ncbi There is no evidence to support the use of aerosolized magnesium for acute asthma
    Gustavo J Rodrigo
    Chest 130:304-5; author reply 305-6. 2006
  34. ncbi Status asthmaticus in children: evidence-based recommendations
    Gustavo J Rodrigo
    Chest 121:667-9. 2002