Eduardo De Stefani

Summary

Affiliation: Departamento de Emergencia
Country: Uruguay

Publications

  1. doi request reprint Meat intake, meat mutagens and risk of lung cancer in Uruguayan men
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Facultad de Medicina, Hospital de Clinicas, Avenida Brasil 3080 department 402, 11300, Montevideo, Uruguay
    Cancer Causes Control 20:1635-43. 2009
  2. doi request reprint Meat consumption, cooking methods, mutagens, and risk of squamous cell carcinoma of the esophagus: a case-control study in Uruguay
    Eduardo De Stefani
    Epidemiology Group, Department of Pathology, School of Medicine, Montevideo, Uruguay
    Nutr Cancer 64:294-9. 2012
  3. doi request reprint Dietary patterns and risk of cancer: a factor analysis in Uruguay
    Eduardo De Stefani
    Departamento de Anatomia Patologica, Grupo de Epidemiologia, Universidad de Clínicas, Facultad de Medicina, Montevideo, Uruguay
    Int J Cancer 124:1391-7. 2009
  4. ncbi request reprint Salted meat consumption and the risk of cancer: a multisite case-control study in Uruguay
    Eduardo De Stefani
    Departamento de Anatomia Patologica, Hospital de Clíínicas, Uruguay
    Asian Pac J Cancer Prev 10:853-7. 2009
  5. pmc Non-alcoholic beverages and risk of bladder cancer in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Montevideo, Uruguay
    BMC Cancer 7:57. 2007
  6. ncbi request reprint Nutrient intake and risk of squamous cell carcinoma of the esophagus: a case-control study in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Montevideo, Uruguay
    Nutr Cancer 56:149-57. 2006
  7. doi request reprint Nutrient patterns and risk of lung cancer: a factor analysis in Uruguayan men
    Eduardo De Stefani
    Departamento de Anatomia Patologica, Facultad de Medicina, Grupo de Epidemiologia, Hospital de Clinicas, Montevideo, Uruguay
    Lung Cancer 61:283-91. 2008
  8. doi request reprint Exploratory factor analysis of squamous cell carcinoma of the esophagus in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clínicas Facultad de Medicina, Montevideo, Uruguay
    Nutr Cancer 60:188-95. 2008
  9. doi request reprint Dietary patterns and risk of bladder cancer: a factor analysis in Uruguay
    Eduardo De Stefani
    Departamento de Anatomia Patologica, Facultad de Medicina, Hospital de Clinicas, Montevideo, Uruguay
    Cancer Causes Control 19:1243-9. 2008
  10. ncbi request reprint The effect of smoking and drinking in oral and pharyngeal cancers: a case-control study in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Facultad de Medicina, Hospital de Clinicas, Avenida Brasil 3080 dep 402, 11300 Montevideo, Uruguay
    Cancer Lett 246:282-9. 2007

Detail Information

Publications40

  1. doi request reprint Meat intake, meat mutagens and risk of lung cancer in Uruguayan men
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Facultad de Medicina, Hospital de Clinicas, Avenida Brasil 3080 department 402, 11300, Montevideo, Uruguay
    Cancer Causes Control 20:1635-43. 2009
    ..To determine the role of meat consumption and related mutagens in the etiology of lung cancer, we conducted a case-control study among Uruguayan males in the time period 1996-2004...
  2. doi request reprint Meat consumption, cooking methods, mutagens, and risk of squamous cell carcinoma of the esophagus: a case-control study in Uruguay
    Eduardo De Stefani
    Epidemiology Group, Department of Pathology, School of Medicine, Montevideo, Uruguay
    Nutr Cancer 64:294-9. 2012
    ..Red meat, lamb, and boiled meat were directly associated with the risk of ESCC, whereas total white meat, poultry, fish, and liver were mainly protective against this malignancy...
  3. doi request reprint Dietary patterns and risk of cancer: a factor analysis in Uruguay
    Eduardo De Stefani
    Departamento de Anatomia Patologica, Grupo de Epidemiologia, Universidad de Clínicas, Facultad de Medicina, Montevideo, Uruguay
    Int J Cancer 124:1391-7. 2009
    ..The study allowed for the reproducibility of the prudent, drinker and Western patterns, whereas the traditional pattern appears to be country specific...
  4. ncbi request reprint Salted meat consumption and the risk of cancer: a multisite case-control study in Uruguay
    Eduardo De Stefani
    Departamento de Anatomia Patologica, Hospital de Clíínicas, Uruguay
    Asian Pac J Cancer Prev 10:853-7. 2009
    ..Previous studies have suggested that a high intake of salted meat may increase the risk of esophageal and stomach cancers, but the results are not conclusive...
  5. pmc Non-alcoholic beverages and risk of bladder cancer in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Montevideo, Uruguay
    BMC Cancer 7:57. 2007
    ..We conducted an additional case-control study in order to further explore the role of non-alcoholic beverages in bladder carcinogenesis...
  6. ncbi request reprint Nutrient intake and risk of squamous cell carcinoma of the esophagus: a case-control study in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Montevideo, Uruguay
    Nutr Cancer 56:149-57. 2006
    ..4 (95% confidence interval, CI = 1.2-1.6), whereas lycopene displayed a strong protective effect (OR = 0.7; 95% CI = 0.6-0.9). The possible role of these and other dietary constituents in esophageal carcinogenesis is discussed...
  7. doi request reprint Nutrient patterns and risk of lung cancer: a factor analysis in Uruguayan men
    Eduardo De Stefani
    Departamento de Anatomia Patologica, Facultad de Medicina, Grupo de Epidemiologia, Hospital de Clinicas, Montevideo, Uruguay
    Lung Cancer 61:283-91. 2008
    ..91-4.40). The carbohydrates pattern was not associated with risk of lung cancer. Although nutrients could be important determinants in the etiology of lung cancer, stop smoking continue to be the major preventive measure for this disease...
  8. doi request reprint Exploratory factor analysis of squamous cell carcinoma of the esophagus in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clínicas Facultad de Medicina, Montevideo, Uruguay
    Nutr Cancer 60:188-95. 2008
    ..Because diet represents a complex set of highly correlated exposures, dietary patterns could be more explicative of the etiology of squamous cell carcinoma of the esophagus than the traditional reductionist approach...
  9. doi request reprint Dietary patterns and risk of bladder cancer: a factor analysis in Uruguay
    Eduardo De Stefani
    Departamento de Anatomia Patologica, Facultad de Medicina, Hospital de Clinicas, Montevideo, Uruguay
    Cancer Causes Control 19:1243-9. 2008
    ..To determine the major dietary patterns associated with bladder cancer risk, we conducted a principal components analysis (PCA) in a case-control study from Uruguay...
  10. ncbi request reprint The effect of smoking and drinking in oral and pharyngeal cancers: a case-control study in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Facultad de Medicina, Hospital de Clinicas, Avenida Brasil 3080 dep 402, 11300 Montevideo, Uruguay
    Cancer Lett 246:282-9. 2007
    ..Our results raise the possibility that oral and pharyngeal carcinomas are in fact different entities. Further studies are needed in order to clarify this important point...
  11. doi request reprint Dietary patterns and risk of advanced prostate cancer: a principal component analysis in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Facultad de Medicina, Hospital de Clinicas, Avenida Brasil 3080 dep 402, 11300 Montevideo, Uruguay
    Cancer Causes Control 21:1009-16. 2010
    ..In order to explore the role of broader eating patterns in the etiology of prostate cancer, we conducted a principal components analysis among Uruguayan men...
  12. ncbi request reprint Dietary patterns and risk of cancer of the oral cavity and pharynx in Uruguay
    Eduardo De Stefani
    Departamento de Patologia, Instituto Nacional de Oncologia, Montevideo, Uruguay
    Nutr Cancer 51:132-9. 2005
    ..0 (95% CI, 4.1-34.6). Our study confirms the important role of dietary factors in oral and pharyngeal cancer risk and suggests that the analysis of dietary patterns is a powerful tool to investigate the links between nutrition and cancer...
  13. ncbi request reprint The role of vegetable and fruit consumption in the aetiology of squamous cell carcinoma of the oesophagus: a case-control study in Uruguay
    Eduardo De Stefani
    Departamento de Patologia, Instituto Nacional de Oncologia, Montevideo, Uruguay
    Int J Cancer 116:130-5. 2005
    ..47, 95% CI 0.34-0.67). The results of our study point towards an important role of fruits in the prevention of squamous cell carcinoma of the oesophagus...
  14. ncbi request reprint Meat consumption, meat cooking and risk of lung cancer among Uruguayan men
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Uruguay
    Asian Pac J Cancer Prev 11:1713-7. 2010
    ..90, 95 % CI 1.99-4.25, p-value for trend<0.0001), boiled red meat was mainly protective. We conclude that salted meat was the main risk factor. The mechanisms could be related to the content of N-nitroso compounds in salted meat...
  15. ncbi request reprint Squamous and small cell carcinomas of the lung: similarities and differences concerning the role of tobacco smoking
    Eduardo De Stefani
    Registro Nacional de Cancer, Avenida Brasil 3080 dep 402, Montevideo, Uruguay
    Lung Cancer 47:1-8. 2005
    ..These results suggests that SCLC display the strongest relation with tobacco smoking than SCC...
  16. ncbi request reprint Supraglottic and glottic carcinomas: epidemiologically distinct entities?
    Eduardo De Stefani
    Registro Nacional de Cancer, Montevideo, Uruguay
    Int J Cancer 112:1065-71. 2004
    ..It could be suggested that concerning tobacco and alcohol effects, supraglottic and glottic squamous cell cancers are probably distinct epidemiologic entities...
  17. ncbi request reprint Cigarette smoking and risk of large cell carcinoma of the lung: a case-control study in Uruguay
    Eduardo De Stefani
    Registro Nacional de Cancer, Avda Brasil 3080 dep 402, Montevideo, Uruguay
    Lung Cancer 43:267-74. 2004
    ..Finally, filter use was not associated with any reduction in risk. It could be concluded that undifferentiated large cell carcinoma of the lung could be included among those lung tumors classified as Kreyberg I cancers...
  18. doi request reprint Dietary patterns and risk of adenocarcinoma of the lung in males: a factor analysis in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Facultad de Medicina, Uruguay
    Nutr Cancer 63:699-706. 2011
    ..54, 95% CI 0.32-0.92) were significantly protective against this malignancy. The results suggests that adenocarcinoma of the lung could be considered a different nosologic entity, compared with the other histologies of lung cancer...
  19. ncbi request reprint Nutrient patterns and risk of squamous cell carcinoma of the esophagus: a factor analysis in uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Montevideo, Uruguay
    Anticancer Res 28:2499-506. 2008
    ..Squamous cell carcinoma of the esophagus is a common disease, with an age-standardized incidence rate of 55 cases per 100,000 persons in the northern counties of Uruguay. These rates are comparable to those observed in Iran and China...
  20. doi request reprint Dietary patterns and risk of cancers of the upper aerodigestive tract: a factor analysis in Uruguay
    Eduardo De Stefani
    Department of Pathology, School of Medicine, University of the Republic, Montevideo, Uruguay
    Nutr Cancer 65:384-9. 2013
    ....
  21. doi request reprint Food groups and risk of prostate cancer: a case-control study in Uruguay
    Hugo Deneo-Pellegrini
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Universidad de la Republica, Montevideo, Uruguay
    Cancer Causes Control 23:1031-8. 2012
    ..The role of foods and beverages has been studied in detail in order to establish probable risk factors for prostate cancer...
  22. ncbi request reprint Alcohol intake and risk of adenocarcinoma of the lung. A case-control study in Uruguay
    Eduardo De Stefani
    Registro Nacional de Cancer, Montevideo, Uruguay
    Lung Cancer 38:9-14. 2002
    ..These findings suggest that wine drinking has a protective effect in adenocarcinoma of the lung, whereas hard liquor increases moderately the risk of this cell type of lung cancer...
  23. ncbi request reprint Food groups and risk of lung cancer in Uruguay
    Eduardo De Stefani
    Registro Nacional de Cancer, Avda Brasi1 3080 dep 402, Montevideo, Uruguay
    Lung Cancer 38:1-7. 2002
    ....
  24. doi request reprint Meat, milk and risk of lymphoid malignancies: a case-control study in Uruguay
    Eduardo De Stefani
    Department of Pathology, School of Medicine, University of the Republic, Montevideo, Uruguay
    Nutr Cancer 65:375-83. 2013
    ..63-3.63). On the other hand, plant foods, particularly total fruits, and alcoholic beverages (mainly red wine) were protective. We could conclude that these foods could play a significant role in the etiology of lymphoid malignancies...
  25. ncbi request reprint Nutrient patterns and risk of breast cancer in Uruguay
    Alvaro L Ronco
    Instituto de Radiología y Centro de Lucha Contra el Cáncer, Centro Hospitalario Pereira Rossell, Montevideo, Uruguay
    Asian Pac J Cancer Prev 11:519-24. 2010
    ..To explore the role of nutrient patterns in the etiology of breast cancer (BC) among Uruguayan women...
  26. ncbi request reprint Diet and adenocarcinoma of the lung: a case-control study in Uruguay
    Eduardo De Stefani
    Registro Nacional de Cancer, Montevideo, Uruguay
    Lung Cancer 35:43-51. 2002
    ..Low consumption of plant foods, and in a lesser degree, high consumption of red meat, total fat and cholesterol contribute to a high risk of adenocarcinoma of the lung...
  27. ncbi request reprint Dietary patterns and risk of ductal carcinoma of the breast: a factor analysis in Uruguay
    Alvaro L Ronco
    Depto De Epidemiología y Método Científico, Facultad de Medicina, Uruguay
    Asian Pac J Cancer Prev 11:1187-93. 2010
    ..17) as well as the fried white meat (OR=2.28) and Western patterns (OR 2.13). Ductal BC shared similar dietary risk patterns as those identified by studies not discriminating between histologic type of breast cancer...
  28. ncbi request reprint Occupational exposures and risk of adenocarcinoma of the lung in Uruguay
    Eduardo De Stefani
    Departamento de Patologia, Instituto Nacional de Oncologia, Montevideo, Uruguay
    Cancer Causes Control 16:851-6. 2005
    ..To investigate occupational risks of lung adenocarcinoma in Uruguay and to confirm a previously reported increased risk among butchers...
  29. ncbi request reprint Nutrient-derived dietary patterns and risk of colorectal cancer: a factor analysis in Uruguay
    Eduardo De Stefani
    Epidemiology Group, Department of Pathology, School of Medicine, UDELAR, Uruguay
    Asian Pac J Cancer Prev 13:231-5. 2012
    ..Since herocyclic amines are formed in the well-done red meat through the action of amino acids and creatine, it is suggestive that this pattern could be an important etiologic agent for colorectal cancer...
  30. ncbi request reprint Dietary patterns and risk of gastric cancer: a case-control study in Uruguay
    Eduardo De Stefani
    Registro Nacional de Cancer, Avenida Brasil 3080 dep 402, Montevideo, Uruguay
    Gastric Cancer 7:211-20. 2004
    ..For this purpose, we included 240 cases and 960 controls...
  31. ncbi request reprint Dietary patterns and risk of laryngeal cancer: an exploratory factor analysis in Uruguayan men
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Montevideo, Uruguay
    Int J Cancer 121:1086-91. 2007
    ..This study also suggests that the analysis of dietary patterns might be a useful approach for investigating nutritional factors implicated in laryngeal carcinogenesis...
  32. doi request reprint Hormonal and metabolic modulation through nutrition: towards a primary prevention of breast cancer
    Alvaro L Ronco
    Depto de Epidemiologia, Facultad de Medicina, IUCLAEH, Prado and Salt Lake P 16, Maldonado, Uruguay
    Breast 19:322-32. 2010
    ..From a medical and ethical viewpoint, it is justified to recommend certain nutritional changes to women, because no adverse side effects are expected to occur...
  33. ncbi request reprint Dietary patterns and risk of colorectal cancer: a factor analysis in uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Uruguay
    Asian Pac J Cancer Prev 12:753-9. 2011
    ..49, 95 % CI 0.28-0.57 for the traditional pattern). In conclusion, whereas the Western pattern was directly associated with colon cancer, the prudent pattern was strongly protective for rectal cancer...
  34. doi request reprint Nutrient-based dietary patterns of head and neck squamous cell cancer: a factor analysis in Uruguay
    Hugo Deneo-Pellegrini
    Epidemiology Group, Department of Pathology, School of Medicine, Avenida Brasil 3080 department 402, 11300, Montevideo, Uruguay
    Cancer Causes Control 24:1167-74. 2013
    ..The aim of this study was to investigate the association between nutrient-based dietary patterns and squamous cell cancers of the head and neck...
  35. ncbi request reprint Food patterns and risk of breast cancer: A factor analysis study in Uruguay
    Alvaro L Ronco
    Departamento de Epidemiologia, Sección de Radiología, Centro Hospitalario Pereira Rossell, Montevideo, Uruguay
    Int J Cancer 119:1672-8. 2006
    ..03, 95% CI 1.11-3.72) and high-fat (OR 2.72, 95%CI 1.16-6.37) dietary patterns. This finding could suggest that gene-dietary interaction could play an important role in breast carcinogenesis...
  36. ncbi request reprint Risk factors for premenopausal breast cancer: a case-control study in Uruguay
    Alvaro L Ronco
    Depto de Epidemiologia, Facultad de Medicina, IUCLAEH, Uruguay
    Asian Pac J Cancer Prev 13:2879-86. 2012
    ..Preventive strategies could broaden their scope if new studies confirm the present results, in view of the limited prevention measures that premenopausal BC currently has...
  37. doi request reprint Maté consumption and risk of oral cancer: Case-control study in Uruguay
    Hugo Deneo-Pellegrini
    Epidemiology Group, Department of Pathology, School of Medicine, Uruguay
    Head Neck 35:1091-5. 2013
    ..In the period 1990 to 2001, a case-control study on oral cancer and maté consumption was conducted at the Cancer Institute of Uruguay...
  38. ncbi request reprint Diabetes, overweight and risk of postmenopausal breast cancer: a case-control study in Uruguay
    Alvaro L Ronco
    Oncology and Radiotherapy Unit, Pereira Rossell Women s Hospital, Montevideo, Uruguay
    Asian Pac J Cancer Prev 13:139-46. 2012
    ..The present results could contribute to define new high risk groups and individuals for primary as well as for secondary prevention, since this pattern linked to the metabolic syndrome is usually not considered for BC prevention...
  39. doi request reprint Rh factor, family history and risk of breast cancer: a case-control study in Uruguay
    Alvaro L Ronco
    Departamento de Epidemiología y Métodos Científicos, Facultad de Medicina, IUCLAEH, Maldonado, Uruguay
    Cancer Detect Prev 32:277-85. 2009
    ..To explore possible relationships among blood factors, family history of breast cancer (BC) and the risk of the disease, a case-control study was carried out in Montevideo, Uruguay...
  40. doi request reprint Mate drinking and esophageal squamous cell carcinoma in South america: pooled results from two large multicenter case-control studies
    Jay H Lubin
    Authors Affiliations Biostatistics Branch and Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland Epidemiology Group, Department of Pathology Department of Pathology, School of Medicine, University of the Republic Deneo Pellegrini, Director, Department of Pathology, Cancer Institute Unit of Oncology and Radiotherapy, Pereira Rossell Women s Hospital, Montevideo IUCLAEH School of Medicine, Maldonado, Uruguay The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, New York Post Graduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil Nubia Muñoz, Cancer Institute of Colombia, Bogota, Colombia Infections and Cancer Epidemiology Group, International Agency for Research on Cancer, Lyon, France and Catalan Institute of Oncology ICO, IDIBELL, CIBERESP, L Hospitalet de Llobregat 08908, Catalonia, Spain
    Cancer Epidemiol Biomarkers Prev 23:107-16. 2014
    ..Maté tea is a nonalcoholic infusion widely consumed in southern South America, and may increase risk of esophageal squamous cell carcinoma (ESCC) and other cancers due to polycyclic aromatic hydrocarbons (PAH) and/or thermal injury...