Derya Unutmaz

Summary

Publications

  1. doi request reprint RORC2: the master of human Th17 cell programming
    Derya Unutmaz
    Department of Microbiology, Department of Pathology, NYU School of Medicine, NY, USA
    Eur J Immunol 39:1452-5. 2009
  2. pmc Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response
    Mark S Sundrud
    Department of Pathology, Harvard Medical School and Immune Disease Institute, Boston, MA 02115, USA
    Science 324:1334-8. 2009
  3. pmc Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells
    Qi Wan
    Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 208:1875-87. 2011
  4. pmc CCR5 is a receptor for Staphylococcus aureus leukotoxin ED
    Francis Alonzo
    Department of Microbiology, New York University School of Medicine, New York, New York 10016, USA
    Nature 493:51-5. 2013
  5. pmc Probing the effector and suppressive functions of human T cell subsets using antigen-specific engineered T cell receptors
    Qi Wan
    Department of Microbiology, New York University School of Medicine, New York, New York, USA
    PLoS ONE 8:e56302. 2013
  6. pmc GARP-TGF-β Complexes Negatively Regulate Regulatory T Cell Development and Maintenance of Peripheral CD4+ T Cells In Vivo
    Angela X Zhou
    Department of Microbiology, New York University School of Medicine, New York, NY 10016
    J Immunol 190:5057-64. 2013
  7. pmc Th17 cells and HIV infection
    Aimee Elhed
    Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA
    Curr Opin HIV AIDS 5:146-50. 2010

Collaborators

Detail Information

Publications7

  1. doi request reprint RORC2: the master of human Th17 cell programming
    Derya Unutmaz
    Department of Microbiology, Department of Pathology, NYU School of Medicine, NY, USA
    Eur J Immunol 39:1452-5. 2009
    ..These findings support the notion that RORC2 is a master switch that initiates a wide range of phenotypic and functional programming during Th17 cell differentiation...
  2. pmc Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response
    Mark S Sundrud
    Department of Pathology, Harvard Medical School and Immune Disease Institute, Boston, MA 02115, USA
    Science 324:1334-8. 2009
    ..These results indicate that the AAR pathway is a potent and selective regulator of inflammatory T cell differentiation in vivo...
  3. pmc Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells
    Qi Wan
    Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 208:1875-87. 2011
    ..Furthermore, these findings suggest that ex vivo analysis of IL-17 expression may greatly underestimate the frequency and pathogenic potential of the human Th17 compartment...
  4. pmc CCR5 is a receptor for Staphylococcus aureus leukotoxin ED
    Francis Alonzo
    Department of Microbiology, New York University School of Medicine, New York, New York 10016, USA
    Nature 493:51-5. 2013
    ..aureus infection, highlighting the importance of CCR5 targeting in S. aureus pathogenesis. Thus, depletion of CCR5(+) leukocytes by LukED suggests a new immune evasion mechanism of S. aureus that can be therapeutically targeted...
  5. pmc Probing the effector and suppressive functions of human T cell subsets using antigen-specific engineered T cell receptors
    Qi Wan
    Department of Microbiology, New York University School of Medicine, New York, New York, USA
    PLoS ONE 8:e56302. 2013
    ....
  6. pmc GARP-TGF-β Complexes Negatively Regulate Regulatory T Cell Development and Maintenance of Peripheral CD4+ T Cells In Vivo
    Angela X Zhou
    Department of Microbiology, New York University School of Medicine, New York, NY 10016
    J Immunol 190:5057-64. 2013
    ..These findings suggest a role for GARP in natural and induced Treg development through activation of bound latent TGF-β and signaling, which negatively regulates GARP expression on Tregs...
  7. pmc Th17 cells and HIV infection
    Aimee Elhed
    Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA
    Curr Opin HIV AIDS 5:146-50. 2010
    ..We discuss the recent findings on Th17 deficiency in HIV/simian immunodeficiency virus (SIV) infection and how this deficiency may impact the mucosal host defenses, potentially contributing to chronic immune activation...