Luis M Vila

Summary

Affiliation: University of Puerto Rico

Publications

  1. ncbi request reprint Early clinical manifestations, disease activity and damage of systemic lupus erythematosus among two distinct US Hispanic subpopulations
    L M Vila
    Department of Internal Medicine, Division of Rheumatology, University of Puerto Rico, Medical Sciences Campus, PO Box 365067, San Juan, Puerto Rico 00936 5067, USA
    Rheumatology (Oxford) 43:358-63. 2004
  2. ncbi request reprint Systemic lupus erythematosus in a multiethnic cohort (LUMINA): XXIX. Elevation of erythrocyte sedimentation rate is associated with disease activity and damage accrual
    Luis M Vila
    Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    J Rheumatol 32:2150-5. 2005
  3. ncbi request reprint Association of serum MIP-1alpha, MIP-1beta, and RANTES with clinical manifestations, disease activity, and damage accrual in systemic lupus erythematosus
    Luis M Vila
    Department of Internal Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    Clin Rheumatol 26:718-22. 2007
  4. ncbi request reprint Systemic lupus erythematosus in a multiethnic US cohort, XXXVII: association of lymphopenia with clinical manifestations, serologic abnormalities, disease activity, and damage accrual
    Luis M Vila
    Division of Rheumatology, Department of Internal Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico
    Arthritis Rheum 55:799-806. 2006
  5. ncbi request reprint Clinical and prognostic value of autoantibodies in puerto Ricans with systemic lupus erythematosus
    L M Vila
    Department of Internal Medicine, Division of Rheumatology, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico
    Lupus 15:892-8. 2006
  6. ncbi request reprint Chronic anemia and thrombocytosis as the initial presentation of Still's disease in an elderly patient
    Luis M Vila
    Department of Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    Gerontology 53:289-92. 2007
  7. ncbi request reprint Systemic lupus erythematosus in a multiethnic US cohort LUMINA LI: anaemia as a predictor of disease activity and damage accrual
    A M Bertoli
    Division of Rheumatology, Department of Medicine, University of Puerto Rico Medical Sciences Campus, PO Box 365067, San Juan, PR 00936 5067
    Rheumatology (Oxford) 46:1471-6. 2007
  8. pmc Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups
    Wenfeng Tan
    David Geffen School of Medicine, Department of Medicine, University of California, Los Angeles, CA 90095 1670, USA
    Arthritis Rheum 63:2755-63. 2011
  9. pmc Systemic lupus erythematosus in a multiethnic US cohort (LUMINA): LXI. Value of C-reactive protein as a marker of disease activity and damage
    Ana M Bertoli
    Department of Medicine, Division of Rheumatology, The University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    J Rheumatol 35:2355-8. 2008
  10. pmc Association of hand or knee osteoarthritis with diabetes mellitus in a population of Hispanics from Puerto Rico
    Mariely Nieves-Plaza
    Puerto Rico Clinical and Translational Research Consortium, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    J Clin Rheumatol 19:1-6. 2013

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Early clinical manifestations, disease activity and damage of systemic lupus erythematosus among two distinct US Hispanic subpopulations
    L M Vila
    Department of Internal Medicine, Division of Rheumatology, University of Puerto Rico, Medical Sciences Campus, PO Box 365067, San Juan, Puerto Rico 00936 5067, USA
    Rheumatology (Oxford) 43:358-63. 2004
    ..To compare the baseline clinical manifestations, immunological features, disease activity and damage accrual in systemic lupus erythematosus (SLE) patients from two US Hispanic subgroups...
  2. ncbi request reprint Systemic lupus erythematosus in a multiethnic cohort (LUMINA): XXIX. Elevation of erythrocyte sedimentation rate is associated with disease activity and damage accrual
    Luis M Vila
    Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    J Rheumatol 32:2150-5. 2005
    ..To determine if different categories of erythrocyte sedimentation rate (ESR) elevation are associated with disease activity and/or damage in systemic lupus erythematosus (SLE)...
  3. ncbi request reprint Association of serum MIP-1alpha, MIP-1beta, and RANTES with clinical manifestations, disease activity, and damage accrual in systemic lupus erythematosus
    Luis M Vila
    Department of Internal Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    Clin Rheumatol 26:718-22. 2007
    ..MIP-1alpha is associated with discoid lupus, and MIP-1beta correlates with damage accrual in SLE. This study suggests that chemokines may have a role in the pathogenesis of SLE...
  4. ncbi request reprint Systemic lupus erythematosus in a multiethnic US cohort, XXXVII: association of lymphopenia with clinical manifestations, serologic abnormalities, disease activity, and damage accrual
    Luis M Vila
    Division of Rheumatology, Department of Internal Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico
    Arthritis Rheum 55:799-806. 2006
    ..To determine if lymphopenia is associated with clinical/immunologic manifestations, disease activity, and disease damage in systemic lupus erythematosus (SLE)...
  5. ncbi request reprint Clinical and prognostic value of autoantibodies in puerto Ricans with systemic lupus erythematosus
    L M Vila
    Department of Internal Medicine, Division of Rheumatology, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico
    Lupus 15:892-8. 2006
    ..These findings provide valuable clinical and prognostic information for this ethnic population...
  6. ncbi request reprint Chronic anemia and thrombocytosis as the initial presentation of Still's disease in an elderly patient
    Luis M Vila
    Department of Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    Gerontology 53:289-92. 2007
    ..Rheumatoid factor and antinuclear antibodies were negative. She responded favorably to prednisone and methotrexate treatment. Anemia and thrombocytosis as well as Still's disease manifestations resolved...
  7. ncbi request reprint Systemic lupus erythematosus in a multiethnic US cohort LUMINA LI: anaemia as a predictor of disease activity and damage accrual
    A M Bertoli
    Division of Rheumatology, Department of Medicine, University of Puerto Rico Medical Sciences Campus, PO Box 365067, San Juan, PR 00936 5067
    Rheumatology (Oxford) 46:1471-6. 2007
    ..To examine if anaemia (and its severity) is associated with disease activity and damage accrual in systemic lupus erythematosus (SLE)...
  8. pmc Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups
    Wenfeng Tan
    David Geffen School of Medicine, Department of Medicine, University of California, Los Angeles, CA 90095 1670, USA
    Arthritis Rheum 63:2755-63. 2011
    ..This study was designed to determine whether genetic variants of PPP2AC are linked to the expression of SLE and specific clinical manifestations and account for the increased expression of PP2Ac...
  9. pmc Systemic lupus erythematosus in a multiethnic US cohort (LUMINA): LXI. Value of C-reactive protein as a marker of disease activity and damage
    Ana M Bertoli
    Department of Medicine, Division of Rheumatology, The University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    J Rheumatol 35:2355-8. 2008
    ..To determine whether C-reactive protein (CRP) measured by a high sensitivity (hs) assay is a surrogate marker of disease activity and damage in systemic lupus erythematosus (SLE)...
  10. pmc Association of hand or knee osteoarthritis with diabetes mellitus in a population of Hispanics from Puerto Rico
    Mariely Nieves-Plaza
    Puerto Rico Clinical and Translational Research Consortium, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    J Clin Rheumatol 19:1-6. 2013
    ..Although a higher prevalence of osteoarthritis (OA) has been reported among diabetes mellitus (DM) patients, inconsistencies and limitations of observational studies have precluded a conclusive association...
  11. pmc Outcome and predictors of kidney disease progression in Puerto Ricans with systemic lupus erythematosus initially presenting with mild renal involvement
    Mariely Nieves-Plaza
    Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico Medical Sciences Campus, San Juan, PR
    J Clin Rheumatol 17:179-84. 2011
    ..The aims of this study were to determine the outcomes and predictors of renal disease progression in Puerto Ricans with systemic lupus erythematosus (SLE) initially presenting mild renal involvement...
  12. pmc Predictors of cardiovascular damage in patients with systemic lupus erythematosus: data from LUMINA (LXVIII), a multiethnic US cohort
    Guillermo J Pons-Estel
    Department of Medicine, Division of Clinical Immunology and Rheumatology, Schools of Medicine and Public Health, The University of Alabama at Birmingham, Birmingham, AL, USA
    Rheumatology (Oxford) 48:817-22. 2009
    ..To determine the features predictive of atherosclerotic cardiovascular damage in patients with SLE...
  13. ncbi request reprint Systemic lupus erythematosus in a multiethnic US cohort (LUMINA L II): relationship between vascular events and the use of hormone replacement therapy in postmenopausal women
    Mónica Fernández
    Division of Clinical Immunology and Rheumatology, Department of Medicine, Schools of Medicine and Public Health, The University of Alabama at Birmingham, 510 20th Street South, Birmingham, AL 35294, USA
    J Clin Rheumatol 13:261-5. 2007
    ..To examine the influence of hormone replacement therapy (HRT) in the occurrence of vascular arterial and venous thrombotic events in postmenopausal women with systemic lupus erythematosus (SLE)...
  14. pmc MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus
    Yun Deng
    Division of Rheumatology, University of California Los Angeles, Los Angeles, California, USA
    PLoS Genet 9:e1003336. 2013
    ..0×10(-19), OR = 1.25 [1.20-1.32]), which confers allelic effect on transcript turnover via differential binding to the epigenetic factor miR-3148...
  15. pmc Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups
    Kenneth M Kaufman
    Division of Rheumatology and The Center for Autoimmune Genomics and Etiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    Ann Rheum Dis 72:437-44. 2013
    ..However, due to the strong linkage disequilibrium between IRAK1 and MECP2, it remains unclear which gene is affected by the underlying causal variant(s) conferring risk of SLE...
  16. pmc Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry
    Paula S Ramos
    Department of Medicine, Medical University of South Carolina, Charleston, SC, USA
    J Rheumatol 40:842-9. 2013
    ..We analyzed variation in reactive intermediate genes for association with SLE in 2 populations with African ancestry...
  17. pmc Factors predictive of thrombotic events in LUMINA, a multi-ethnic cohort of SLE patients (LXXII)
    Paula I Burgos
    Department of Medicine, Division of Clinical Immunology and Rheumatology, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    Rheumatology (Oxford) 49:1720-5. 2010
    ..Thrombosis is an important cause of morbidity and mortality in SLE. We have explored the factors associated with time to the occurrence of thrombotic events in SLE patients to expand our cohort's previous observations...
  18. pmc Impact of managed care health insurance system for indigent patients with rheumatoid arthritis in Puerto Rico
    Yesenia Santiago-Casas
    Division of Rheumatology, Department of Medicine, University of Puerto Rico Medical Sciences Campus, PO Box 365067, 00936 5067 San Juan, Puerto Rico
    Clin Rheumatol 32:763-9. 2013
    ..Efforts should be undertaken to curtail the gap of health disparities among these Hispanic patients in order to improve their long-term outcomes...
  19. pmc Impact of age on clinical manifestations and outcome in Puerto Ricans with rheumatoid arthritis
    Yesenia Santiago-Casas
    Division of Rheumatology, Department of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    Ethn Dis 20:S1-191-5. 2010
    ..Thus, we determined the demographic characteristics, clinical manifestations, comorbidities, pharmacologic profile, and functional status among Puerto Ricans with RA of different age groups...
  20. pmc Association of discoid lupus erythematosus with clinical manifestations and damage accrual in a multiethnic lupus cohort
    Yesenia Santiago-Casas
    University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico 00936
    Arthritis Care Res (Hoboken) 64:704-12. 2012
    ..To determine the clinical manifestations and disease damage associated with discoid rash in a large multiethnic systemic lupus erythematosus (SLE) cohort...
  21. pmc Renal damage is the most important predictor of mortality within the damage index: data from LUMINA LXIV, a multiethnic US cohort
    Maria I Danila
    Department of Medicine, Division of Clinical Immunology and Rheumatology, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA
    Rheumatology (Oxford) 48:542-5. 2009
    ..Damage accrual in SLE has been previously shown to be an independent predictor of mortality. We sought to discern which SLICC Damage Index (SDI) domains are the most important predictors of survival in SLE...
  22. pmc Utilization of health services and prescription patterns among lupus patients followed by primary care physicians and rheumatologists in Puerto Rico
    María J Molina
    Department of Medicine, Division of Rheumatology, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico, USA
    Ethn Dis 18:S2-205-10. 2008
    ..To examine the utilization of health services and prescription patterns among patients with systemic lupus erythematosus (SLE) followed by primary care physicians and rheumatologists in Puerto Rico...
  23. ncbi request reprint The impact of increased body mass index on systemic lupus erythematosus: data from LUMINA, a multiethnic cohort (LUMINA XLVI) [corrected]
    Sumapa Chaiamnuay
    Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Clin Rheumatol 13:128-33. 2007
    ....
  24. pmc Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus
    Travis Hughes
    Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA
    Ann Rheum Dis 71:694-9. 2012
    ..The genetic basis of sexual dimorphism in SLE is not clearly defined. A study was undertaken to examine sex-specific genetic effects among SLE susceptibility loci...
  25. pmc Prevalence of systemic lupus erythematosus and associated comorbidities in Puerto Rico
    María J Molina
    Department of Internal Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    J Clin Rheumatol 13:202-4. 2007
    ..To examine the prevalence of systemic lupus erythematosus (SLE) and its associated comorbidities in patients from Puerto Rico using a database from a health insurance company...
  26. pmc Efficacy of two cyclophosphamide regimens for the treatment of lupus nephritis in Puerto Ricans: low vs. standard dose
    Lesliane E Castro-Santana
    Division of Rheumatology, Department of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    Ethn Dis 20:S1-116-21. 2010
    ..Thus, we evaluated the efficacy of two established treatment protocols for lupus nephritis (low-dose versus standard-dose cyclophosphamide) in Puerto Ricans with systemic lupus erythematosus (SLE)...
  27. pmc Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility
    Jian Zhao
    Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS Genet 7:e1002079. 2011
    ....
  28. doi request reprint Rheumatology practice profiles in teaching and community settings in Puerto Rico: implications to subspecialty training
    Amarie M Negrón
    Division of Rheumatology, Department of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico
    J Clin Rheumatol 19:67-71. 2013
    ..University-based fellowship training programs may not always provide the required experience to manage common and less complex medical conditions usually seen at the community setting. Few studies have addressed this concern...
  29. pmc Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus
    Chaim O Jacob
    The Lupus Genetic Group, Department of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 106:6256-61. 2009
    ..This demonstration of an X chromosome gene as a disease susceptibility factor in human SLE raises the possibility that the gender difference in SLE may in part be attributed to sex chromosome genes...