S Denic

Summary

Affiliation: Faculty of Medicine and Health Sciences
Country: United Arab Emirates

Publications

  1. pmc Acute Thrombocytopenia, Leucopenia, and Multiorgan Dysfunction: The First Case of SFTS Bunyavirus outside China?
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, P O Box 17666, Al Ain, UAE
    Case Rep Infect Dis 2011:204056. 2011
  2. pmc Hemoglobin A2 Lowered by Iron Deficiency and α -Thalassemia: Should Screening Recommendation for β -Thalassemia Change?
    Srdjan Denic
    Department of Medicine, College of Medicine and Health Sciences, United Arab Emirates University, P O Box 17666, Al Ain, Abu Dhabi, UAE
    ISRN Hematol 2013:858294. 2013
  3. doi request reprint β-Thalassemia in Abu Dhabi: consanguinity and tribal stratification are major factors explaining the high prevalence of the disease
    Srdjan Denic
    Department of Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates
    Hemoglobin 37:351-8. 2013
  4. doi request reprint Type 2 diabetes: the genetic conflict hypothesis
    S Denic
    College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, PO Box 17666, United Arab Emirates
    Med Hypotheses 80:436-40. 2013
  5. doi request reprint Choice of kin in consanguineous marriages: effects of altruism and ecological factors
    Srdjan Denic
    Faculty of Medicine and Health Sciences, UAE University, Al Ain, Abu Dhabi, United Arab Emirates
    Ann Hum Biol 37:738-53. 2010
  6. pmc Consanguineous marriages and endemic malaria: can inbreeding increase population fitness?
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, Abu Dhabi, UAE
    Malar J 7:150. 2008
  7. doi request reprint On some novel aspects of consanguineous marriages
    S Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates
    Public Health Genomics 14:162-8. 2011
  8. ncbi request reprint Consanguinity affects selection of alpha-thalassemia genotypes and the size of populations under selection pressure from malaria
    Srdjan Denic
    Faculty of Medicine and Health Sciences, UAE University, Al Ain, Abu Dhabi, United Arab Emirates
    Ann Hum Biol 34:620-31. 2007
  9. pmc Erythrocyte reference values in Emirati people with and without α+ thalassemia
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, Al Ain, UAE
    BMC Blood Disord 11:1. 2011
  10. ncbi request reprint Risk of cancer in an inbred population
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, Abu Dhabi, United Arab Emirates
    Cancer Detect Prev 31:263-9. 2007

Detail Information

Publications25

  1. pmc Acute Thrombocytopenia, Leucopenia, and Multiorgan Dysfunction: The First Case of SFTS Bunyavirus outside China?
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, P O Box 17666, Al Ain, UAE
    Case Rep Infect Dis 2011:204056. 2011
    ..The clinical manifestations, the time of disease onset, and geographical link of the patient with the region in which the disease is endemic suggest that the patient had SFTS bunyavirus infection...
  2. pmc Hemoglobin A2 Lowered by Iron Deficiency and α -Thalassemia: Should Screening Recommendation for β -Thalassemia Change?
    Srdjan Denic
    Department of Medicine, College of Medicine and Health Sciences, United Arab Emirates University, P O Box 17666, Al Ain, Abu Dhabi, UAE
    ISRN Hematol 2013:858294. 2013
    ..2 and 3.5% were at a risk of false negative diagnosis of BTT. Since iron deficiency and α (+)-thalassemia are both common and both lower HbA2, modifications in screening recommendations for BTT are proposed...
  3. doi request reprint β-Thalassemia in Abu Dhabi: consanguinity and tribal stratification are major factors explaining the high prevalence of the disease
    Srdjan Denic
    Department of Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates
    Hemoglobin 37:351-8. 2013
    ..1 in 226 couples, significantly (p = 0.02) more than expected by taking only inbreeding into account. Although β-thal mutations are relatively rare, the burden of β-thal disease is increased eight-fold by tribalism and consanguinity. ..
  4. doi request reprint Type 2 diabetes: the genetic conflict hypothesis
    S Denic
    College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, PO Box 17666, United Arab Emirates
    Med Hypotheses 80:436-40. 2013
    ..This hypothesis links human mate selection with the risk of developing DM2...
  5. doi request reprint Choice of kin in consanguineous marriages: effects of altruism and ecological factors
    Srdjan Denic
    Faculty of Medicine and Health Sciences, UAE University, Al Ain, Abu Dhabi, United Arab Emirates
    Ann Hum Biol 37:738-53. 2010
    ..Studying the variation of kin preferences in diverse inbred societies may provide some answers to this paradox...
  6. pmc Consanguineous marriages and endemic malaria: can inbreeding increase population fitness?
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, Abu Dhabi, UAE
    Malar J 7:150. 2008
    ..The aim of this study was to explore the overall effects of inbreeding on the fitness of a population infested with malaria...
  7. doi request reprint On some novel aspects of consanguineous marriages
    S Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates
    Public Health Genomics 14:162-8. 2011
    ..We contend that a better appreciation of our inherent biases and potential genetic benefits of inbreeding in specific ecological conditions would help us to appreciate the wider picture of consanguinity...
  8. ncbi request reprint Consanguinity affects selection of alpha-thalassemia genotypes and the size of populations under selection pressure from malaria
    Srdjan Denic
    Faculty of Medicine and Health Sciences, UAE University, Al Ain, Abu Dhabi, United Arab Emirates
    Ann Hum Biol 34:620-31. 2007
    ..In populations with alpha(+)-thalassemia gene deletion, the practice of consanguineous marriages is common...
  9. pmc Erythrocyte reference values in Emirati people with and without α+ thalassemia
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, Al Ain, UAE
    BMC Blood Disord 11:1. 2011
    ..For such populations, separate reference values for normal and α+ thalassemia homozygotes are needed...
  10. ncbi request reprint Risk of cancer in an inbred population
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, Abu Dhabi, United Arab Emirates
    Cancer Detect Prev 31:263-9. 2007
    ..In spite of a high prevalence of consanguineous marriages in Asia and Africa, there has been little epidemiological research on the effect of inbreeding on cancer risk...
  11. ncbi request reprint Nutritional iron deficiency: an evolutionary perspective
    Srdjan Denic
    Faculty of Medicine and Health Sciences, UAE University, Al Ain, Abu Dhabi, United Arab Emirates
    Nutrition 23:603-14. 2007
    ..We suggest that, due to a long evolutionary persistence of iron deficiency, efforts at its prevention will take a long time to be effective...
  12. ncbi request reprint Incestuous gene in consanguinophilia and incest: toward a consilience theory of incest taboo
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, P O Box 17666, Al Ain, Abu Dhabi, United Arab Emirates
    Med Hypotheses 66:52-8. 2006
    ..We propose that the incestuous anti-w allele was co-selected with some of the genes protective against malaria because anti-w facilitates mating between genetically close individuals whose offspring better survive malaria...
  13. ncbi request reprint Parental consanguinity and risk of breast cancer: a population-based case-control study
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, U A E University, U A E
    Med Sci Monit 11:CR415-9. 2005
    ..The objective of this case-control study was to examine whether parental consanguinity and different levels of inbreeding affect the risk and pathology characteristics of breast cancer...
  14. ncbi request reprint Cancer by negative heterosis: breast and ovarian cancer excess in hybrids of inbred ethnic groups
    S Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, P O Box 17666, Al Ain, Abu Dhabi, United Arab Emirates
    Med Hypotheses 64:1002-6. 2005
    ..Result was birth of a large number of inter-ethnic/brotherhood hybrids (heterozygotes), some of which have developed cancer by heterosis...
  15. ncbi request reprint Quality of age data in patients from developing countries
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, UAE
    J Public Health (Oxf) 26:168-71. 2004
    ..We analysed single-year age distribution and terminal digit preference in cancer patients from developing countries...
  16. ncbi request reprint Consanguinity as risk factor for cervical carcinoma
    S Denic
    UAE University, Al Ain, United Arab Emirates
    Med Hypotheses 60:321-4. 2003
    ..Westermarck's effect prevents incest in nuclear family. In consanguineous family, it extends to spouses, producing mild sexual antipathy. Because of high prevalence of consanguinity worldwide, it is important to test this hypothesis...
  17. ncbi request reprint Breast cancer, consanguinity, and lethal tumor genes: simulation of BRCA1/2 prevalence over 40 generations
    Srdjan Denic
    Department of Medicine, Faculty of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates
    Int J Mol Med 10:713-9. 2002
    ..A drift phenomenon may exert a major effect on the carrier rate. Consanguinity may explain part of the worldwide variation of breast cancer incidence...
  18. pmc Prevalence, phenotype and inheritance of benign neutropenia in Arabs
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, Al Ain, UAE
    BMC Blood Disord 9:3. 2009
    ..CONCLUSION: Arabs have a high prevalence of benign neutropenia that may be inherited as an autosomal dominant trait...
  19. ncbi request reprint Consanguinity and family history of cancer in children with leukemia and lymphomas
    A Bener
    Department of Community Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates
    Cancer 92:1-6. 2001
    ..The family history of cancer is more often positive among ALL cases than controls--consanguinity having no effect...
  20. ncbi request reprint Knowledge, attitudes, and practices related to breast cancer screening: a survey of Arabic women
    A Bener
    Department of Community Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain
    J Cancer Educ 16:215-20. 2001
    ..Incorporating breast cancer screening into day-to-day clinical care leads to early diagnosis and decreases mortality. Patients' participation in screening depends on their knowledge and attitudes, other barriers, and physician behavior...
  21. pmc Consanguinity decreases risk of breast cancer--cervical cancer unaffected
    S Denic
    Department of Internal Medicine, Department of Community Medicine, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, AI Ain, United Arab Emirates
    Br J Cancer 85:1675-9. 2001
    ..Having consanguineous parents decreases the risk of breast cancer especially in younger women, risk of cervical cancer being unaffected...
  22. ncbi request reprint Genetic benefits of consanguinity through selection of genotypes protective against malaria
    Srdjan Denic
    Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, United Arab Emirates
    Hum Biol 79:145-58. 2007
    ....
  23. doi request reprint Germline genomic homozygosity and cancer risk
    Srdjan Denic
    JAMA 300:169-70; author reply 170. 2008
  24. ncbi request reprint BRCA1 and BRCA2 mutations in breast cancer patients from Saudi Arabia
    Srdjan Denic
    Saudi Med J 24:696; author reply 696-7. 2003
  25. doi request reprint Validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaires for Arabic-speaking Populations
    Manal A Awad
    University of Sharjah, Sharjah, United Arab Emirates
    Ann N Y Acad Sci 1138:146-54. 2008
    ..In summary, the Arabic versions of the EORTC QLQ-C30 and QLQ-BR23 are reliable and valid tools for assessment of quality of life in Arab patients with cancer...