Amr Amin

Summary

Affiliation: Faculty of Medicine and Health Sciences
Country: United Arab Emirates

Publications

  1. ncbi request reprint EGFR and wingless signaling pathways interact to specify the ocellar pattern in Drosophila
    Amr Amin
    Biology Department, UAE University, Al Ain, UAE
    Acta Histochem 105:285-93. 2003
  2. ncbi request reprint Oxidative stress mediates drug-induced hepatotoxicity in rats: a possible role of DNA fragmentation
    Amr Amin
    U A E University, Al Ain, P O Box 17551, United Arab Emirates
    Toxicology 208:367-75. 2005
  3. pmc Overview of major classes of plant-derived anticancer drugs
    Amr Amin
    Department of Biology, UAE University, U A E
    Int J Biomed Sci 5:1-11. 2009
  4. pmc A standardized extract of Ginkgo biloba neutralizes cisplatin-mediated reproductive toxicity in rats
    Amr Amin
    Biology Department, United Arab Emirates University, Al Ain 17551, UAE
    J Biomed Biotechnol 2012:362049. 2012
  5. pmc Neural network assessment of herbal protection against chemotherapeutic-induced reproductive toxicity
    Amr Amin
    Biology Department, UAE University, University St, Al Ain 17551, UAE
    Theor Biol Med Model 9:1. 2012
  6. doi request reprint Saffron: a potential candidate for a novel anticancer drug against hepatocellular carcinoma
    Amr Amin
    Biology Department, Faculty of Science, United Arab Emirates University, Al Ain, United Arab Emirates
    Hepatology 54:857-67. 2011
  7. doi request reprint Texture analysis of liver fibrosis microscopic images: a study on the effect of biomarkers
    Amr Amin
    Biology Department, Faculty of Science, UAE University, Al Ain, United Arab Emirates
    Acta Biochim Biophys Sin (Shanghai) 43:193-203. 2011
  8. doi request reprint Ketoconazole-induced testicular damage in rats reduced by Gentiana extract
    Amr Amin
    Biology Department, UAE University, P O Box 17551, Al Ain, UAE
    Exp Toxicol Pathol 59:377-84. 2008
  9. ncbi request reprint The protective effect of Tribulus terrestris in diabetes
    Amr Amin
    Biology Department, United Arab Emirates University, PO Box 17551, Al Ain, Abu Dhabi, United Arab Emirates
    Ann N Y Acad Sci 1084:391-401. 2006
  10. ncbi request reprint Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer
    Amr Amin
    Biology Department, UAE University, Al Ain, United Arab Emirates
    Cell Biol Int 29:687-94. 2005

Detail Information

Publications25

  1. ncbi request reprint EGFR and wingless signaling pathways interact to specify the ocellar pattern in Drosophila
    Amr Amin
    Biology Department, UAE University, Al Ain, UAE
    Acta Histochem 105:285-93. 2003
    ..This study suggests a novel role of wingless in specifying the Drosophila dorsal head via blocking vein expression in this region...
  2. ncbi request reprint Oxidative stress mediates drug-induced hepatotoxicity in rats: a possible role of DNA fragmentation
    Amr Amin
    U A E University, Al Ain, P O Box 17551, United Arab Emirates
    Toxicology 208:367-75. 2005
    ..These results strongly suggest a positive correlation between hepatotoxicity and DNA fragmentation. Moreover, this study also implicates calcium as a potential mediator of the drug-induced oxidative stress associated with hepatotoxicity...
  3. pmc Overview of major classes of plant-derived anticancer drugs
    Amr Amin
    Department of Biology, UAE University, U A E
    Int J Biomed Sci 5:1-11. 2009
    ....
  4. pmc A standardized extract of Ginkgo biloba neutralizes cisplatin-mediated reproductive toxicity in rats
    Amr Amin
    Biology Department, United Arab Emirates University, Al Ain 17551, UAE
    J Biomed Biotechnol 2012:362049. 2012
    ..The present results provide further insights into the mechanisms of protection against CIS-induced reproductive toxicity and confirm the essential antioxidant potential of a GB extract...
  5. pmc Neural network assessment of herbal protection against chemotherapeutic-induced reproductive toxicity
    Amr Amin
    Biology Department, UAE University, University St, Al Ain 17551, UAE
    Theor Biol Med Model 9:1. 2012
    ..We also show here that herbal protection against CIS-induced reproductive toxicity utilizing classic methodologies is validated using neural network analysis...
  6. doi request reprint Saffron: a potential candidate for a novel anticancer drug against hepatocellular carcinoma
    Amr Amin
    Biology Department, Faculty of Science, United Arab Emirates University, Al Ain, United Arab Emirates
    Hepatology 54:857-67. 2011
    ..This report also shows some evidence that saffron protects rat liver from cancer via modulating oxidative damage and suppressing inflammatory response...
  7. doi request reprint Texture analysis of liver fibrosis microscopic images: a study on the effect of biomarkers
    Amr Amin
    Biology Department, Faculty of Science, UAE University, Al Ain, United Arab Emirates
    Acta Biochim Biophys Sin (Shanghai) 43:193-203. 2011
    ..TA results were consistent with both BIF and serum marker measurements...
  8. doi request reprint Ketoconazole-induced testicular damage in rats reduced by Gentiana extract
    Amr Amin
    Biology Department, UAE University, P O Box 17551, Al Ain, UAE
    Exp Toxicol Pathol 59:377-84. 2008
    ..Most of the KET-induced effects were greatly decreased with the concomitant application of GEN extract. This study suggests a protective role of GEN extract that could be attributed to its antioxidant properties...
  9. ncbi request reprint The protective effect of Tribulus terrestris in diabetes
    Amr Amin
    Biology Department, United Arab Emirates University, PO Box 17551, Al Ain, Abu Dhabi, United Arab Emirates
    Ann N Y Acad Sci 1084:391-401. 2006
    ..Histopathological examination revealed significant recovery of liver in herb-treated rats. This investigation suggests that the protective effect of TT for STZ-induced diabetic rats may be mediated by inhibiting oxidative stress...
  10. ncbi request reprint Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer
    Amr Amin
    Biology Department, UAE University, Al Ain, United Arab Emirates
    Cell Biol Int 29:687-94. 2005
    ..To our knowledge, this is the first study that suggests significant chemopreventive effects of Fenugreek seeds against breast cancer...
  11. ncbi request reprint Effects of Roselle and Ginger on cisplatin-induced reproductive toxicity in rats
    Amr Amin
    Department of Biology, United Arab Emirates University, Al Ain 17555, United Arab Emirates
    Asian J Androl 8:607-12. 2006
    ..To evaluate the protective effects of Hibiscus sabdariffa (Roselle) and Zingiber officinale (Ginger) against cisplatin-induced reproductive toxicity in rats and to study the mechanisms underlying these effects...
  12. ncbi request reprint New platinum and ruthenium complexes--the latest class of potential chemotherapeutic drugs--a review of recent developments in the field
    Amr Amin
    Department of Biology, UAE University, P O Box 17551, UAE
    Mini Rev Med Chem 9:1489-503. 2009
    ..The article also refers to more recent work in the area of molybdenum and copper(II) chemistry...
  13. ncbi request reprint Hepatoprotective effects of Hibiscus, Rosmarinus and Salvia on azathioprine-induced toxicity in rats
    A Amin
    Biology Department, UAE University, Al Ain, P O Box 17555, UAE
    Life Sci 77:266-78. 2005
    ..To our knowledge, this report is the first that shows hepatoprotective effects of Hibiscus, Rosmarinus and Salvia species against Azathioprine-induced acute liver damage...
  14. ncbi request reprint Herbal extracts counteract cisplatin-mediated cell death in rat testis
    Amr Amin
    Biology Department, United Arab Emirates University, Al Ain 17551, United Arab Emirates
    Asian J Androl 10:291-7. 2008
    ..Their protective effects against CIS-induced apoptosis in testicular and epididymal sperms is also investigated...
  15. ncbi request reprint The anti-cancer charm of flavonoids: a cup-of-tea will do!
    Amr Amin
    Biology Department, College of Science, UAE University, UAE
    Recent Pat Anticancer Drug Discov 2:109-17. 2007
    ..This review will bring the reader up to date on the current knowledge and research available in the field of flavonoids and hormone-dependent cancers, and many of the submitted patents that exploit flavonoids...
  16. doi request reprint Zizyphus spina-christi protects against carbon tetrachloride-induced liver fibrosis in rats
    Amr Amin
    Biology Department, College of Science, UAE University, P O Box 17551, Al Ain, United Arab Emirates
    Food Chem Toxicol 47:2111-9. 2009
    ..These results demonstrate that administration of ZSC may be useful in the treatment and prevention of hepatic fibrosis...
  17. ncbi request reprint Vitamin E ameliorates some biochemical parameters in normal and diabetic rats
    Mariam Al-Shamsi
    Department of Anatomy, Faculty of Medicine and Health Sciences, UAE University, P O Box 17666, Al Ain, United Arab Emirates
    Ann N Y Acad Sci 1084:411-31. 2006
    ..The plasma level of electrolytes, such as calcium and sodium, also changed significantly (P < 0.00001) after the oral administration of vitamin E. Vitamin E ameliorates the metabolic and biochemical parameters of diabetic rats...
  18. ncbi request reprint Apium graveolens modulates sodium valproate-induced reproductive toxicity in rats
    Alaaeldin A Hamza
    Biology Department, College of Science, UAE University, Al Ain, UAE
    J Exp Zool A Ecol Genet Physiol 307:199-206. 2007
    ..graveolens extract against experimental VPA-induced toxicity. Apigenin content was estimated and was shown as a major fraction of the A. graveolens extract...
  19. ncbi request reprint Effect of vitamin C on liver and kidney functions in normal and diabetic rats
    Mariam Al-Shamsi
    Department of Anatomy, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, United Arab Emirates
    Ann N Y Acad Sci 1084:371-90. 2006
    ..00001) after oral administration of vitamin C. Antioxidants, such as vitamin C, may ameliorate the biochemical parameters of diabetic rats...
  20. pmc The anticancer effect of saffron in two p53 isogenic colorectal cancer cell lines
    Khuloud Bajbouj
    Biology Department, Faculty of Science, UAE University, Al Ain, United Arab Emirates
    BMC Complement Altern Med 12:69. 2012
    ..Saffron extract, a natural product, has been shown to induce apoptosis in several tumor cell lines. Nevertheless, the p53-dependency of saffron's mechanism of action in colon cancer remains unexplored...
  21. ncbi request reprint Vitamin E decreases the hyperglucagonemia of diabetic rats
    Mariam Al-Shamsi
    Department of Anatomy, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, United Arab Emirates
    Ann N Y Acad Sci 1084:432-41. 2006
    ..05) reduction in plasma glucagon level in rats treated before and after the onset of diabetes. Vitamin E may ameliorate some diabetic complication via reduction in the level of circulating glucagon...
  22. ncbi request reprint Beneficial effect of vitamin E on the metabolic parameters of diabetic rats
    Maryam S Al Shamsi
    Department of Anatomy, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates
    Mol Cell Biochem 261:35-42. 2004
    ..Moreover, vitamin E also improved OGTT in diabetic rats compared to untreated diabetics. In conclusion, vitamin E may play a role in glucose metabolism and thus be a useful adjuvant therapy in type I diabetes...
  23. ncbi request reprint The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats
    A Hamza
    Biology Department, College of Science, UAE University, Al Ain, United Arab Emirates
    Cell Biol Toxicol 24:63-73. 2008
    ..American Fork, UT, USA) of Withania somnifera (300 mg/kg). Thus, Withania may play a role in the protection against cardiotoxicity and thus might be a useful adjuvant therapy where doxorubicin is the cancer-treating drug...