Volodymyr I Lushchak

Summary

Affiliation: Precarpathian National University named after Vassyl Stefanyk
Country: Ukraine

Publications

  1. ncbi request reprint Budding yeast Saccharomyces cerevisiae as a model to study oxidative modification of proteins in eukaryotes
    Volodymyr I Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Acta Biochim Pol 53:679-84. 2006
  2. doi request reprint Sodium nitroprusside induces mild oxidative stress in Saccharomyces cerevisiae
    Oleh V Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Redox Rep 13:144-52. 2008
  3. ncbi request reprint [Anaerobic catabolism of protein in fish]
    V I Lushchak
    Stefanik Prykarpatsky University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 73:18-24. 2001
  4. ncbi request reprint Temperature increase results in oxidative stress in goldfish tissues. 1. Indices of oxidative stress
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, 76025, Ivano Frankivsk, Ukraine
    Comp Biochem Physiol C Toxicol Pharmacol 143:30-5. 2006
  5. ncbi request reprint Temperature increase results in oxidative stress in goldfish tissues. 2. Antioxidant and associated enzymes
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, 76025, Ivano Frankivsk, Ukraine
    Comp Biochem Physiol C Toxicol Pharmacol 143:36-41. 2006
  6. ncbi request reprint The effect of buthionine sulfoximine on the glutathione level in goldfish tissues
    V I Lushchak
    Vassyl Stefanyk Precarpathian University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 77:35-8. 2005
  7. ncbi request reprint Regulatory protein Yap1 is involved in response of yeast Saccharomyces cerevisiae to nitrosative stress
    O V Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, 76025, Ukraine
    Biochemistry (Mosc) 75:629-64. 2010
  8. doi request reprint AMP-deaminase from goldfish white muscle: regulatory properties and redistribution under exposure to high environmental oxygen level
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko St, Ivano Frankivsk, 76025, Ukraine
    Fish Physiol Biochem 35:443-52. 2009
  9. ncbi request reprint Diethyldithiocarbamate injection induces transient oxidative stress in goldfish tissues
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk, Ukraine
    Chem Biol Interact 170:1-8. 2007
  10. ncbi request reprint Inactivation of genes encoding superoxide dismutase modifies yeast response to S-nitrosoglutathione-induced stress
    O V Lushchak
    Department of Biochemistry, Vasyl Stefanyk Precarpathian National University, Ivano Frankivsk, 76025, Ukraine
    Biochemistry (Mosc) 74:445-51. 2009

Collaborators

Detail Information

Publications65

  1. ncbi request reprint Budding yeast Saccharomyces cerevisiae as a model to study oxidative modification of proteins in eukaryotes
    Volodymyr I Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Acta Biochim Pol 53:679-84. 2006
    ....
  2. doi request reprint Sodium nitroprusside induces mild oxidative stress in Saccharomyces cerevisiae
    Oleh V Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Redox Rep 13:144-52. 2008
    ..It is suggested, that under aerobic conditions, the SNP effects are connected with induction of mild oxidative/nitrosative stress...
  3. ncbi request reprint [Anaerobic catabolism of protein in fish]
    V I Lushchak
    Stefanik Prykarpatsky University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 73:18-24. 2001
    ..If amino acids are metabolized to lipids and ammonium and carbon dioxide are excreted from the organism, general level of organism oxidation is increased, because the most oxidized amino acid part is excreted in environment...
  4. ncbi request reprint Temperature increase results in oxidative stress in goldfish tissues. 1. Indices of oxidative stress
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, 76025, Ivano Frankivsk, Ukraine
    Comp Biochem Physiol C Toxicol Pharmacol 143:30-5. 2006
    ..87) suggesting that the former was used to reduce the latter over the experiment. It is concluded that the redox balance in goldfish tissues is strictly maintained probably contributing to the high tolerance of this species to heat shock...
  5. ncbi request reprint Temperature increase results in oxidative stress in goldfish tissues. 2. Antioxidant and associated enzymes
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, 76025, Ivano Frankivsk, Ukraine
    Comp Biochem Physiol C Toxicol Pharmacol 143:36-41. 2006
    ..Several enzymes (SOD, GST, GR) responded to stress in coordinated manner...
  6. ncbi request reprint The effect of buthionine sulfoximine on the glutathione level in goldfish tissues
    V I Lushchak
    Vassyl Stefanyk Precarpathian University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 77:35-8. 2005
    ..We conclude that BSO can be used to deplete GSH-eq in goldfish liver and brain, but attention should be paid to species-specific variations in BSO effects...
  7. ncbi request reprint Regulatory protein Yap1 is involved in response of yeast Saccharomyces cerevisiae to nitrosative stress
    O V Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, 76025, Ukraine
    Biochemistry (Mosc) 75:629-64. 2010
    ..Therefore, we conclude that these results in combination with previous data clearly demonstrate the involvement of Yap1p in upregulation of superoxide dismutase and catalase in yeast cells in response to nitrosative stress...
  8. doi request reprint AMP-deaminase from goldfish white muscle: regulatory properties and redistribution under exposure to high environmental oxygen level
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko St, Ivano Frankivsk, 76025, Ukraine
    Fish Physiol Biochem 35:443-52. 2009
    ..A spatial-temporal redistribution may be among the mechanisms regulating enzyme operation in vivo. Possible regulatory mechanisms of AMP-deaminase function in fish muscle are discussed...
  9. ncbi request reprint Diethyldithiocarbamate injection induces transient oxidative stress in goldfish tissues
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk, Ukraine
    Chem Biol Interact 170:1-8. 2007
    ..Different actions of the superoxide anion in cellular metabolism and possible consequences of the impairment of superoxide dismutase are discussed...
  10. ncbi request reprint Inactivation of genes encoding superoxide dismutase modifies yeast response to S-nitrosoglutathione-induced stress
    O V Lushchak
    Department of Biochemistry, Vasyl Stefanyk Precarpathian National University, Ivano Frankivsk, 76025, Ukraine
    Biochemistry (Mosc) 74:445-51. 2009
    ..A GSNO-induced increase in oxidized glutathione level in the studied yeast strains might account for cell killing by GSNO due to the development of oxidative/nitrosative stress...
  11. ncbi request reprint Growth on ethanol results in co-ordinated Saccharomyces cerevisiae response to inactivation of genes encoding superoxide dismutases
    Oleh V Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Redox Rep 12:181-8. 2007
    ..No changes in the activity of glutathione reductase and protein carbonyl levels support the idea that SOD-deficient cells are not exposed to strong oxidative stress during exponential growth of yeast cultures on ethanol...
  12. doi request reprint Adaptive response to oxidative stress: Bacteria, fungi, plants and animals
    Volodymyr I Lushchak
    Department of Biochemistry and Biotechnology, Vassyl Stefanyk Precarpathian National University, 57 Shevchenko Str, 76025, Ivano Frankivsk, Ukraine
    Comp Biochem Physiol C Toxicol Pharmacol 153:175-90. 2011
    ..The idea is to provide starting points from which we can develop novel tools and hypothesis to facilitate meaningful investigations in the physiology and biochemistry of organismic response to oxidative stress...
  13. ncbi request reprint Free radical oxidation of proteins and its relationship with functional state of organisms
    V I Lushchak
    Department of Biochemistry, Stefanyk Precarpathian National University, Ivano Frankivsk, 76025, Ukraine
    Biochemistry (Mosc) 72:809-27. 2007
    ..The final part of the article is devoted to possible ways of protecting proteins against oxidation in vivo...
  14. ncbi request reprint The effect of temperature increase on the expression of manganese superoxide dismutase in tissues of common carp Cyprinus carpio
    V I Lushchak
    Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 79:87-91. 2007
    ..This work suggests that the activity of Mn-SOD in carp is regulated by environmental conditions through transcriptional, translational and post-translational mechanisms, the particular mechanism used being dependent upon the tissue type...
  15. ncbi request reprint Regulation of AMP-deaminase activity from white muscle of common carp Cyprinus carpio
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, Ivano Frankivsk, Ukraine
    Comp Biochem Physiol B Biochem Mol Biol 149:362-9. 2008
    ..Free radicals inactivated the enzyme, decreasing V(max) by one-half but not affecting S(0.5) or Hill coefficient. Possible regulatory mechanisms of AMP-deaminase activity in fish muscle are discussed...
  16. doi request reprint Environmentally induced oxidative stress in aquatic animals
    Volodymyr I Lushchak
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, Ivano Frankivsk, Ukraine
    Aquat Toxicol 101:13-30. 2011
    ..The last part marks some perspectives in the study of oxidative stress in hydrobionts, which, in addition to classic use, became more and more popular to address general biological questions such as development, aging and pathologies...
  17. ncbi request reprint Hypoxia induces oxidative stress in tissues of a goby, the rotan Perccottus glenii
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, 76025, Ivano Frankivsk, Ukraine
    Comp Biochem Physiol B Biochem Mol Biol 148:390-7. 2007
    ..Taken together, these data show that hypoxia resulted in the development of oxidative stress and a compensatory changes of antioxidant enzymes in the tissues...
  18. doi request reprint Catalase modifies yeast Saccharomyces cerevisiae response towards S-nitrosoglutathione-induced stress
    Oleh V Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Redox Rep 13:283-91. 2008
    ..The obtained data demonstrate that exposure of yeast cells to the *NO-donor S-nitrosoglutathione induced mild oxidative/nitrosative stress and Yap1p may co-ordinate the up-regulation of antioxidant enzymes under these conditions...
  19. ncbi request reprint Possible pathways involved in activation of catalase and superoxide dismutase with sodium nitroprusside in yeast Saccharomyces cerevisiae
    O V Lushchak
    Vasyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 81:34-9. 2009
    ..This response is mediated by Yap1p. Despite the increase of SOD activity in yeast cells possibly includes the activation of the present apoprotein by Ccs1p, the ways of nitric oxide regulation of Ccs1p activity are still unclear...
  20. doi request reprint Chromium(III) induces oxidative stress in goldfish liver and kidney
    Oleh V Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk 76025, Ukraine
    Aquat Toxicol 93:45-52. 2009
    ..A comparison of Cr3+ effects on goldfish liver and kidney metabolism indicates that the trivalent ion induces stronger oxidative stress than Cr6+ at the same concentrations...
  21. ncbi request reprint Comparative study of free and bound glycolytic enzymes from sea scorpion brain
    V I Lushchak
    Karadag Branch of Southern Sea Biology Institute, Kurortne, Feodosia, Crimea, Ukraine
    Biochem Cell Biol 76:609-14. 1998
    ..The possible physiological role of the binding of these glycolytic enzymes to subcellular structures is discussed...
  22. ncbi request reprint Oxidative stress and mechanisms of protection against it in bacteria
    V I Lushchak
    Department of Natural Sciences, Stefanyk Precarpathian University, Ivano Frankivsk, 76025, Ukraine
    Biochemistry (Mosc) 66:476-89. 2001
    ..Special attention is given to the expression of so-called antioxidant and associated enzymes as protection mechanisms and to the space-time organization of the response of bacteria to oxidative stress...
  23. ncbi request reprint Influence of exercise on the activity and the distribution between free and bound forms of glycolytic and associated enzymes in tissues of horse mackerel
    V I Lushchak
    Department of Natural Sciences, Precarpathian University, 57 Shevchenko Str, Ivano Frankivsk, 76000 Ukraine
    Braz J Med Biol Res 34:1055-64. 2001
    ..Changes in enzyme activities and in binding interactions with subcellular particulate matter appear to support the altered demands of tissue energy metabolism during exercise...
  24. ncbi request reprint [Effect of destruction of Escherichia coli cells on the catalytic ability of catalase]
    H M Semchyshin
    Stephanic Pricarpathian University, Ivano Frankivsk State Medical Academy, Ukraine
    Ukr Biokhim Zh 73:24-8. 2001
    ....
  25. ncbi request reprint [Effect of hypoxia on carbohydrate metabolism in scorpion tissues]
    V I Lushchak
    Vassyl Stefanik Precarpathian University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 74:100-5. 2002
    ..In muscle the activities of phosphofructokinase and phosphoglucoisomerase decreased. Mechanisms of carbohydrates metabolism regulation under hypoxia are discussed...
  26. ncbi request reprint Pdr12p-dependent and -independent fluorescein extrusion from baker's yeast cells
    Volodymyr Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Acta Biochim Pol 55:595-601. 2008
    ..It can be suggested that the membrane protein Pdr12 is involved in fluorescein extrusion from the yeast cells, but component(s) other than Pdr12p is (are) also important...
  27. ncbi request reprint [Activity and properties of phosphofructokinase from while muscle of the horse mackerel Trachurus mediterraneus during simulation due to swimming]
    V I Lushchak
    Stephanyk Precarpathian University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 74:71-5. 2002
    ..3-fold). The mechanisms involving in stable modification of PFK under different swimming regimens are discussed...
  28. ncbi request reprint Oxidative stress in yeast
    V I Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, 57 Shevchenko Str, Ivano Frankivsk, Ukraine
    Biochemistry (Mosc) 75:281-96. 2010
    ..Some examples demonstrating the use of yeast for investigation of apoptosis, aging, and some human diseases are given in the conclusion part...
  29. ncbi request reprint Hypoxia and recovery perturb free radical processes and antioxidant potential in common carp (Cyprinus carpio) tissues
    Volodymyr I Lushchak
    Department of Biochemistry, Faculty of Natural Sciences, Vassyl Stefanyk Precarpathian University, 57 Shevchenko Str, 76025 Ivano Frankivsk, Ukraine
    Int J Biochem Cell Biol 37:1319-30. 2005
    ....
  30. ncbi request reprint Catalases protect cellular proteins from oxidative modification in Saccharomyces cerevisiae
    Volodymyr I Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, 57 Shevchenko Str, 76025 Ivano Frankivsk, Ukraine
    Cell Biol Int 29:187-92. 2005
    ..1-fold higher level of carbonyl proteins than that of wild-type strain. Our data suggest that in vivo catalases may protect glucose-6-phosphate dehydrogenase against oxidative inactivation...
  31. ncbi request reprint Hyperoxia results in transient oxidative stress and an adaptive response by antioxidant enzymes in goldfish tissues
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University, 57 Shevchenko Str, 76025 Ivano Frankivsk, Ukraine
    Int J Biochem Cell Biol 37:1670-80. 2005
    ..The results suggest that liver glutathione-S-transferase plays an important role in detoxifying end products of lipid peroxidation accumulated under hyperoxia stress...
  32. pmc Buffer modulation of menadione-induced oxidative stress in Saccharomyces cerevisiae
    Oleh V Lushchak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Redox Rep 14:214-20. 2009
    ..In vitro, aconitase was more quickly inactivated in 50 mM carbonate, than in 50 mM phosphate buffer. The possible involvement of the carbonate radical in these processes is discussed...
  33. doi request reprint Antioxidant system efficiently protects goldfish gills from Ni(2+)-induced oxidative stress
    Olga I Kubrak
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk 76025, Ukraine
    Chemosphere 90:971-6. 2013
    ....
  34. doi request reprint Goldfish exposure to cobalt enhances hemoglobin level and triggers tissue-specific elevation of antioxidant defenses in gills, heart and spleen
    Olga I Kubrak
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk, 76025, Ukraine
    Comp Biochem Physiol C Toxicol Pharmacol 155:325-32. 2012
    ..The data show that fish exposure to 50-150 mg L(-1) of Co(2+) elevates blood hemoglobin level, mimicking effects of hypoxia, and causes the activation of defense systems against ROS...
  35. doi request reprint Chromium effects on free radical processes in goldfish tissues: comparison of Cr(III) and Cr(VI) exposures on oxidative stress markers, glutathione status and antioxidant enzymes
    Olha I Kubrak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk, 76025, Ukraine
    Comp Biochem Physiol C Toxicol Pharmacol 152:360-70. 2010
    ..Chromium exposure had very little effect on the activities of GR or G6PDH. These data show that both chromium ions induced oxidative stress in goldfish tissues and affected the activity of antioxidant and associated enzymes...
  36. doi request reprint Oxidative stress responses in blood and gills of Carassius auratus exposed to the mancozeb-containing carbamate fungicide Tattoo
    Olga I Kubrak
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk 76025, Ukraine
    Ecotoxicol Environ Saf 85:37-43. 2012
    ..It is clear that goldfish respond to the presence of waterborne pesticide by adjusting antioxidant defenses through upregulation of activities of antioxidant and associated enzymes...
  37. doi request reprint S-nitrosoglutathione-induced toxicity in Drosophila melanogaster: Delayed pupation and induced mild oxidative/nitrosative stress in eclosed flies
    Oleksandr V Lozinsky
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk 76025, Ukraine
    Comp Biochem Physiol A Mol Integr Physiol 164:162-70. 2013
    ..Among the parameters tested, aconitase activity and developmental end points may be useful early indicators of toxicity caused by GSNO...
  38. doi request reprint Nickel induces hyperglycemia and glycogenolysis and affects the antioxidant system in liver and white muscle of goldfish Carassius auratus L
    Olga I Kubrak
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk 76025, Ukraine
    Ecotoxicol Environ Saf 80:231-7. 2012
    ....
  39. ncbi request reprint Coordinated response of goldfish antioxidant defenses to environmental stress
    Tetyana V Bagnyukova
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, 76025 Ivano Frankivsk, Ukraine
    Aquat Toxicol 78:325-31. 2006
    ....
  40. doi request reprint Tissue specificity in nickel uptake and induction of oxidative stress in kidney and spleen of goldfish Carassius auratus, exposed to waterborne nickel
    Olga I Kubrak
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk 76025, Ukraine
    Aquat Toxicol 118:88-96. 2012
    ..Further, as Ni accumulation in this organ was negligible, Ni-toxicity in spleen may be minimized by efficient exclusion of this otherwise toxic metal...
  41. doi request reprint Cobalt-induced oxidative stress in brain, liver and kidney of goldfish Carassius auratus
    Olha I Kubrak
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, Ivano Frankivsk 76025, Ukraine
    Chemosphere 85:983-9. 2011
    ..Taken together, these data show that exposure of fish to Co²⁺ ions results in the development of oxidative stress and the activation of defense systems in different goldfish tissues...
  42. doi request reprint Low toxic herbicide Roundup induces mild oxidative stress in goldfish tissues
    Oleh V Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk 76025, Ukraine
    Chemosphere 76:932-7. 2009
    ..However, catalase activity increased in both liver and kidney of herbicide-exposed fish. To our knowledge this is the first study to demonstrate a systematic response by the antioxidant systems of fish to Roundup exposure...
  43. doi request reprint The effect of potassium dichromate on free radical processes in goldfish: possible protective role of glutathione
    Oleh V Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Street, Ivano Frankivsk 76025, Ukraine
    Aquat Toxicol 87:108-14. 2008
    ....
  44. ncbi request reprint Adaptive response of antioxidant enzymes to catalase inhibition by aminotriazole in goldfish liver and kidney
    Tetyana V Bagnyukova
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, 76025, Ivano Frankivsk, Ukraine
    Comp Biochem Physiol B Biochem Mol Biol 142:335-41. 2005
    ..Glutathione-S-transferase activity also correlated inversely with catalase (R2=0.86). Hence, the response to catalase depletion involves compensatory changes in the activities of enzymes of glutathione metabolism...
  45. doi request reprint Sodium nitroprusside toxicity in Drosophila melanogaster: delayed pupation, reduced adult emergence, and induced oxidative/nitrosative stress in eclosed flies
    Oleksandr V Lozinsky
    Department of Biochemistry and Biotechnology, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Arch Insect Biochem Physiol 80:166-85. 2012
    ..The study also suggests that the toxicity of SNP may arise not just from its direct effects, but also from its decomposition products such as nitric oxide and iron ions...
  46. doi request reprint Acetate but not propionate induces oxidative stress in bakers' yeast Saccharomyces cerevisiae
    Halyna M Semchyshyn
    Department of Biochemistry and Biotechnology, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Redox Rep 16:15-23. 2011
    ..The results are discussed from the point of view that acetate induces a prooxidant effect in vivo, whereas propionate does not...
  47. doi request reprint Drosophila melanogaster larvae fed by glucose and fructose demonstrate difference in oxidative stress markers and antioxidant enzymes of adult flies
    Oleh V Lushchak
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk 76025, Ukraine
    Comp Biochem Physiol A Mol Integr Physiol 160:27-34. 2011
    ..It also substantially depends on fly sex, comprising presumably levels of protein carbonyls and lipid peroxides, as well as catalase and SOD activities in males and G6PDH activity in females...
  48. doi request reprint Trivalent chromium induces oxidative stress in goldfish brain
    Oleh V Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk, 76025, Ukraine
    Chemosphere 75:56-62. 2009
    ..Therefore, it can be concluded that although Cr(3+) exposure induced oxidative stress in goldfish brain, it failed to enhance the efficiency of the antioxidant system in the organ...
  49. doi request reprint The golden root, Rhodiola rosea, prolongs lifespan but decreases oxidative stress resistance in yeast Saccharomyces cerevisiae
    Maria M Bayliak
    Department of Biochemistry and Biotechnology, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Phytomedicine 18:1262-8. 2011
    ..cerevisiae cells, what sensitizes yeast cells to oxidative stress at exponential phase, but induces adaptation in stationary phase cells demonstrating the positive effect on yeast survival without activation of major antioxidant enzymes...
  50. ncbi request reprint Effects of different environmental oxygen levels on free radical processes in fish
    Volodymyr I Lushchak
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, 76025, Ivano Frankivsk, Ukraine
    Comp Biochem Physiol B Biochem Mol Biol 144:283-9. 2006
    ..A scheme on possible ways of regulating antioxidant enzymes by different oxygen levels is proposed...
  51. doi request reprint Cytotoxicity of chromium ions may be connected with induction of oxidative stress
    Olena Yu Vasylkiv
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk, 76025, Ukraine
    Chemosphere 80:1044-9. 2010
    ..This indicates that analysis of plasma can be used as a good early nonlethal diagnostic marker of fish intoxication by transition metal ions...
  52. ncbi request reprint Oxidative stress and antioxidant defenses in goldfish liver in response to short-term exposure to arsenite
    Tetyana V Bagnyukova
    Department of Biochemistry, Precarpathian National University, Ivano Frankivsk, Ukraine
    Environ Mol Mutagen 48:658-65. 2007
    ..The findings suggest that goldfish livers cope with arsenic-induced oxidative stress mainly through adaptive changes in the glutathione pool and antioxidant enzymes...
  53. doi request reprint Production and properties of alpha-amylase from Bacillus sp. BKL20
    Olha I Kubrak
    Department of Biochemistry, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Can J Microbiol 56:279-88. 2010
    ..It also showed good resistance to both oxidizing (H2O2) and denaturating (urea) agents...
  54. doi request reprint Balance between macronutrients affects life span and functional senescence in fruit fly Drosophila melanogaster
    Oleh V Lushchak
    Department of Biochemistry and Biotechnology, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk 76025, Ukraine
    J Gerontol A Biol Sci Med Sci 67:118-25. 2012
    ....
  55. doi request reprint Fructose and glucose differentially affect aging and carbonyl/oxidative stress parameters in Saccharomyces cerevisiae cells
    Halyna M Semchyshyn
    Department of Biochemistry and Biotechnology, Vassyl Stefanyk Precarpathian National University, 57 Shevchenko Str, 76025 Ivano Frankivsk, Ukraine
    Carbohydr Res 346:933-8. 2011
    ..It should be noted that carbohydrate restriction used in this study does not reveal a significant difference between markers of aging and carbonyl/oxidative stress in yeasts cultivated on glucose and fructose...
  56. doi request reprint Inactivation of genes, encoding tocopherol biosynthetic pathway enzymes, results in oxidative stress in outdoor grown Arabidopsis thaliana
    Nadia M Semchuk
    Department of Biochemistry, Precarpathian National University named after Vassyl Stefanyk, Ivano Frankivsk, Ukraine
    Plant Physiol Biochem 47:384-90. 2009
    ..These results demonstrate in plants that tocopherols play a crucial role for growth of plants under outdoor conditions by preventing oxidation of cellular components...
  57. ncbi request reprint Catalase inhibition by amino triazole induces oxidative stress in goldfish brain
    Tetyana V Bagnyukova
    Department of Biochemistry, Institute of Natural Sciences, Vassyl Stefanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Brain Res 1052:180-6. 2005
    ..Possible functions of catalase in the maintenance of prooxidant/antioxidant balance in goldfish brain are discussed...
  58. ncbi request reprint Unusual AMP-deaminase solubilization from teleost fish white muscle
    V I Lushchak
    Karadag Branch of Southern Seas Biology Institute, Kurortne, Feodosia, Crimea
    Biochem Mol Biol Int 43:685-94. 1997
    ....
  59. doi request reprint Transient effects of 2,4-dichlorophenoxyacetic acid (2,4-D) exposure on some metabolic and free radical processes in goldfish white muscle
    Olga I Kubrak
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk 76025, Ukraine Electronic address
    Food Chem Toxicol 59:356-61. 2013
    ..Thus, the short term exposure of goldfish to the selected concentrations of 2,4-D does not substantially affect their white muscle, suggesting the absence of any effect under the environmentally relevant concentrations. ..
  60. doi request reprint Goldfish can recover after short-term exposure to 2,4-dichlorophenoxyacetate: use of blood parameters as vital biomarkers
    Olga I Kubrak
    Department of Biochemistry and Biotechnology, Precarpathian National University named after Vassyl Stefanyk, 57 Shevchenko Str, Ivano Frankivsk, 76025, Ukraine
    Comp Biochem Physiol C Toxicol Pharmacol 157:259-65. 2013
    ..These data indicate that 2,4-D has toxicological effects on goldfish that can be monitored with multiple diagnostic tests using non-lethal blood testing...
  61. ncbi request reprint [pH-dependency of Escherichia coli catalase activity under modified culture conditions]
    H M Semchyshyn
    Stefanyk Precarpathian University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 74:34-41. 2002
    ..coli strain. Investigation of another strain of E. coli K12 AB1157 confirmed this idea where the activity peak with acid pH-optimum was not detected...
  62. ncbi request reprint Modification of pyruvate kinase and lactate dehydrogenase in foot muscle of the sea mussel Mytilus galloprovincialis under anaerobiosis and recovery
    V I Lushchak
    Karadag Branch of Southern Sea Biology Institute, National Academy of Sciences of Ukraine, Feodosia Crimea, Ukraine
    Braz J Med Biol Res 30:381-5. 1997
    ..The possible role of reversible phosphorylation in the regulation of pyruvate kinase and lactate dehydrogenase properties is discussed...
  63. ncbi request reprint Influence of polyethylene glycol on lactate dehydrogenase
    V I Lushchak
    Karadag Branch of Southern Sea Biology Institute, National Academy of Sciences of Ukraine, Crimea, Ukraine
    Biochem Mol Biol Int 44:425-31. 1998
    ..Enzyme preincubation with PEG suppresses also the formation of ternary inactive complex NAD-pyruvate-LDH...
  64. ncbi request reprint Effect of VTE1 AND VTE4 gene inactivation on salt stress response in Arabidopsis thaliana
    N Semchuk
    Vassyl Stephanyk Precarpathian National University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 80:48-54. 2008
    ..thaliana. Salt stress did not change the concentrations of protein carbonyl groups and activities of catalase...
  65. ncbi request reprint [Effect of aminotriazole on the activity of catalase and glucose-6-phosphate dehydrogenase in tissues of two frog species--Rana ridibunda and Rana esculenta]
    O V Lushchak
    Vassyl Stefanyk Precarpathian University, Ivano Frankivsk, Ukraine
    Ukr Biokhim Zh 75:45-50. 2003
    ..The activity of G6PDH of AMT-treated frogs R. esculenta was higher comparing to control group. Possible ways of compensation of antioxidant defense under catalase inhibition are discussed...