F Zagouri

Summary

Country: UK

Publications

  1. pmc Bilateral synchronous breast carcinomas followed by a metastasis to the gallbladder: a case report
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, School of Medicine, University of Athens, Greece
    World J Surg Oncol 5:101. 2007
  2. pmc What parameters affect pain in core biopsy?
    George C Zografos
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens, 114 V Sofias Ave, Athens 116 27, Greece
    Eur Radiol 18:1144-5. 2008
  3. doi request reprint Hsp90 inhibitors in breast cancer: a systematic review
    Flora Zagouri
    Department of Clinical Therapeutics, Alexandra Hospital, Medical School, University of Athens, Vas Sofias Ave and Lourou str, Athens 11521, Greece Electronic address
    Breast 22:569-78. 2013
  4. doi request reprint Pertuzumab in breast cancer: a systematic review
    Flora Zagouri
    Comprehensive Cancer Center Vienna, Department of Medicine I Division of Oncology, Medical University of Vienna, Austria Department of Clinical Therapeutics, Alexandra Hospital, Medical School, University of Athens, Greece Electronic address
    Clin Breast Cancer 13:315-24. 2013
  5. doi request reprint Molecularly targeted therapies in metastatic pancreatic cancer: a systematic review
    Flora Zagouri
    Comprehensive Cancer Center Vienna, Department of Medicine I, Medical University of Vienna, Vienna, Austria
    Pancreas 42:760-73. 2013
  6. pmc Aromatase inhibitors with or without gonadotropin-releasing hormone analogue in metastatic male breast cancer: a case series
    F Zagouri
    Department of Medicine I Division of Oncology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria
    Br J Cancer 108:2259-63. 2013
  7. doi request reprint MMP-2 -1306C>T polymorphism in breast cancer: a case-control study in a South European population
    Flora Zagouri
    Department of Clinical Therapeutics, Alexandra Hospital, Medical School, University of Athens, Vas Sofias Ave and Lourou str, 11521, Athens, Greece
    Mol Biol Rep 40:5035-40. 2013
  8. doi request reprint Serum MMPs and TIMPs: may be predictors of breast carcinogenesis?
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens, Greece
    Clin Chim Acta 412:537-40. 2011
  9. doi request reprint Intrathecal administration of trastuzumab for the treatment of meningeal carcinomatosis in HER2-positive metastatic breast cancer: a systematic review and pooled analysis
    Flora Zagouri
    Department of Clinical Therapeutics, Alexandra Hospital, Medical School, University of Athens, Athens, Greece
    Breast Cancer Res Treat 139:13-22. 2013
  10. ncbi request reprint Prophylactic mastectomy: an appraisal
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens, Athens, Greece
    Am Surg 79:205-12. 2013

Collaborators

Detail Information

Publications48

  1. pmc Bilateral synchronous breast carcinomas followed by a metastasis to the gallbladder: a case report
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, School of Medicine, University of Athens, Greece
    World J Surg Oncol 5:101. 2007
    ..Breast cancer is usually associated with metastases to lungs, bones and liver. Breast carcinoma metastasizing to the gallbladder is very rare...
  2. pmc What parameters affect pain in core biopsy?
    George C Zografos
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens, 114 V Sofias Ave, Athens 116 27, Greece
    Eur Radiol 18:1144-5. 2008
  3. doi request reprint Hsp90 inhibitors in breast cancer: a systematic review
    Flora Zagouri
    Department of Clinical Therapeutics, Alexandra Hospital, Medical School, University of Athens, Vas Sofias Ave and Lourou str, Athens 11521, Greece Electronic address
    Breast 22:569-78. 2013
    ..Pharmacological inhibition of Hsp90 shows great promise in breast cancer treatment. This is the first systematic review to synthesize all available data and to evaluate the efficacy and safety of Hsp90 inhibitors in breast cancer...
  4. doi request reprint Pertuzumab in breast cancer: a systematic review
    Flora Zagouri
    Comprehensive Cancer Center Vienna, Department of Medicine I Division of Oncology, Medical University of Vienna, Austria Department of Clinical Therapeutics, Alexandra Hospital, Medical School, University of Athens, Greece Electronic address
    Clin Breast Cancer 13:315-24. 2013
    ..The promising role of pertuzumab in the neoadjuvant and adjuvant settings remains to be further investigated and established in the future. ..
  5. doi request reprint Molecularly targeted therapies in metastatic pancreatic cancer: a systematic review
    Flora Zagouri
    Comprehensive Cancer Center Vienna, Department of Medicine I, Medical University of Vienna, Vienna, Austria
    Pancreas 42:760-73. 2013
    ....
  6. pmc Aromatase inhibitors with or without gonadotropin-releasing hormone analogue in metastatic male breast cancer: a case series
    F Zagouri
    Department of Medicine I Division of Oncology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria
    Br J Cancer 108:2259-63. 2013
    ..Data regarding the safety and effectiveness of aromatase inhibitors (AIs) as monotherapy or combined with gonadotropin-releasing hormone (GnRH) analogue in male breast cancer are scarce...
  7. doi request reprint MMP-2 -1306C>T polymorphism in breast cancer: a case-control study in a South European population
    Flora Zagouri
    Department of Clinical Therapeutics, Alexandra Hospital, Medical School, University of Athens, Vas Sofias Ave and Lourou str, 11521, Athens, Greece
    Mol Biol Rep 40:5035-40. 2013
    ..MMP-2 -1306C>T polymorphism does not seem to be a risk factor for breast cancer in South European population; however, a trend towards a favorable association with survival has been observed...
  8. doi request reprint Serum MMPs and TIMPs: may be predictors of breast carcinogenesis?
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens, Greece
    Clin Chim Acta 412:537-40. 2011
    ....
  9. doi request reprint Intrathecal administration of trastuzumab for the treatment of meningeal carcinomatosis in HER2-positive metastatic breast cancer: a systematic review and pooled analysis
    Flora Zagouri
    Department of Clinical Therapeutics, Alexandra Hospital, Medical School, University of Athens, Athens, Greece
    Breast Cancer Res Treat 139:13-22. 2013
    ..However, clinical trials are urgently needed to establish the definite role of IT trastuzumab in HER2-positive metastatic breast cancer patients with MC...
  10. ncbi request reprint Prophylactic mastectomy: an appraisal
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens, Athens, Greece
    Am Surg 79:205-12. 2013
    ..This review examines key issues regarding prophylactic mastectomy: the selection of patients, its effectiveness, its limitations, convergence/divergence in existing guidelines, and future perspectives...
  11. doi request reprint Taxanes for breast cancer during pregnancy: a systematic review
    Flora Zagouri
    Department of Clinical Therapeutics, Alexandra Hospital, University of Athens, Greece
    Clin Breast Cancer 13:16-23. 2013
    ..In conclusion, available data suggest that taxanes may potentially play a promising role in the optimal therapeutic strategy of patients with breast cancer diagnosed during pregnancy...
  12. doi request reprint Trastuzumab administration during pregnancy: a systematic review and meta-analysis
    Flora Zagouri
    Division of Oncology, Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Borgschkegasse 8a, 1090, Vienna, Austria
    Breast Cancer Res Treat 137:349-57. 2013
    ..However, for women who become accidentally pregnant during trastuzumab administration and wish to continue pregnancy, trastuzumab should be stopped and pregnancy could be allowed to continue...
  13. doi request reprint mTOR inhibitors in breast cancer: a systematic review
    Flora Zagouri
    Comprehensive Cancer Center Vienna, Department of Medicine I Division of Oncology, Medical University of Vienna, Austria
    Gynecol Oncol 127:662-72. 2012
    ..Regarding temsirolimus, it seems that the agent may play, in the future, a role in the treatment of metastatic breast cancer; importantly, however, there is an unmet need to find its optimal target subpopulation...
  14. pmc Imprint cytology on microcalcifications excised by vacuum-assisted breast biopsy: a rapid preliminary diagnosis
    Maria Fotou
    Department of Cytology, Hippocratio Hospital, Athens, Greece
    World J Surg Oncol 5:40. 2007
    ..To evaluate imprint cytology in the context of specimens with microcalcifications derived from Vacuum-Assisted Breast Biopsy (VABB)...
  15. pmc Is zero underestimation feasible? Extended Vacuum-Assisted Breast Biopsy in solid lesions - a blind study
    George C Zografos
    1st Department of Surgery, School of Medicine, Athens University, Greece
    World J Surg Oncol 5:53. 2007
    ..The main disadvantage is underestimation, which might render the management of atypical ductal hyperplasia (ADH), and ductal carcinoma in situ (DCIS) difficult. This study aims to develop and assess a modified way of performing VABB...
  16. pmc Pheochromocytoma associated with neurofibromatosis type 1: concepts and current trends
    George N Zografos
    Third Department of Surgery, G, Gennimatas Hospital, Athens, Greece
    World J Surg Oncol 8:14. 2010
    ..Neurofibromatosis Type 1(NF-1) has autosomal dominant inheritance with complete penetrance, variable expression and a high rate of new mutation. Pheochromocytoma occurs in 0.1%-5.7% of patients with NF-1...
  17. pmc Gestational trophoblastic neoplasia with retroperitoneal metastases: a fatal complication
    Nikolaos Thomakos
    Department of Clinical and Therapeutics, Alexandra Hospital, School of Medicine, University of Athens, Greece
    World J Surg Oncol 8:114. 2010
    ..The therapeutic approach of this condition includes both surgical intervention and chemotherapy. The prognosis depends on many prognostic factors that determine the stage of the disease...
  18. pmc Secondary breast lymphoma diagnosed by vacuum-assisted breast biopsy: a case report
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens 114, Vas Sofias Ave, Athens 116 27, Greece
    J Med Case Reports 1:113. 2007
    ..On the other hand, Vacuum-assisted breast biopsy (VABB) is a minimally invasive technique with ever-growing use for the diagnosis of mammographically detected, non-palpable breast lesions...
  19. pmc Health-related quality of life in vacuum-assisted breast biopsy: short-term effects, long-term effects and predictors
    Philip J Domeyer
    Breast Unit, First Department of Propaedeutic Surgery, Hippokratio Hospital, Medical School, University of Athens, 108 Vas Sofias Ave, Athens 11527, Greece
    Health Qual Life Outcomes 8:11. 2010
    ....
  20. pmc Breast ductal endoscopy: how many procedures qualify?
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens 114, Vas Sofias Ave, Athens 116 27, Greece
    BMC Res Notes 2:115. 2009
    ..The purpose of this study is to determine the point (number of procedures during training) beyond which ductal endoscopy is successfully performed...
  21. pmc Volume of blood suctioned during vacuum-assisted breast biopsy predicts later hematoma formation
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens 114, Vas Sofias Ave, Athens 116 27, Greece
    BMC Res Notes 3:70. 2010
    ..To evaluate whether the volume of blood suctioned during vacuum-assisted breast biopsy (VABB) is associated with hematoma formation and progression, patient's age and histology of the lesion...
  22. pmc Decreased Hsp90 expression in infiltrative lobular carcinoma: an immunohistochemical study
    Flora Zagouri
    Breast Unit, 1stDepartment of Propaedeutic Surgery, Hippokratio Hospital, School of Medicine, University of Athens, Athens, Greece
    BMC Cancer 10:409. 2010
    ..This study aims to assess Hsp90 expression in infiltrative lobular carcinomas of the breast...
  23. pmc Circulating levels of matrix metalloproteinase-9 (MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and their complex MMP-9/NGAL in breast cancer disease
    Xeni Provatopoulou
    Research Center, Hellenic Anticancer Institute, Athens, Greece
    BMC Cancer 9:390. 2009
    ..We aim to evaluate the serum expression of MMP-9, NGAL and their complex (MMP-9/NGAL) during the diagnostic work-up of women with breast abnormalities and investigate their correlation with disease severity...
  24. pmc Hsp90 in the continuum of breast ductal carcinogenesis: Evaluation in precursors, preinvasive and ductal carcinoma lesions
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, School of Medicine, University of Athens, Greece
    BMC Cancer 10:353. 2010
    ....
  25. doi request reprint Molecularly targeted therapies in unresectable-metastatic gastric cancer: a systematic review
    Flora Zagouri
    Department of Clinicals and Therapeutics, Alexandra Hospital, School of Medicine, University of Athens, Greece
    Cancer Treat Rev 37:599-610. 2011
    ....
  26. ncbi request reprint Molecular markers in epithelial ovarian cancer: their role in prognosis and therapy
    F Zagouri
    Department of Clinical Therapeutics, Alexandra Hospital, University of Athens School of Medicine, Athens, Greece
    Eur J Gynaecol Oncol 31:268-77. 2010
    ..It is tempting to anticipate the gradual integration of molecular profiling in clinical practice...
  27. pmc Non-blood medical care in gynecologic oncology: a review and update of blood conservation management schemes
    Maria Simou
    Department of Obstetrics and Gynecology, Alexandra Hospital, School of Medicine, University of Athens, Greece
    World J Surg Oncol 9:142. 2011
    ....
  28. pmc Treatment of early uterine sarcomas: disentangling adjuvant modalities
    Flora Zagouri
    Department of Clinical Therapeutics, Alexandra Hospital, University of Athens, School of Medicine, Athens, Greece
    World J Surg Oncol 7:38. 2009
    ..However, more trials are needed to address these issues, especially, their sequential application. Patients with uterine sarcomas should be referred to large academic centers for participation in clinical trials...
  29. pmc Precursors and preinvasive lesions of the breast: the role of molecular prognostic markers in the diagnostic and therapeutic dilemma
    Flora Zagouri
    Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens, Athens, Greece
    World J Surg Oncol 5:57. 2007
    ..This knowledge has the potential to be of importance in the therapeutic decisions presenting in the common clinical practice...
  30. pmc Heat shock protein90 in lobular neoplasia of the breast
    Flora Zagouri
    1st Department of Propaedeutic Surgery, Breast Unit, Hippokratio Hospital, University of Athens, Athens, Greece
    BMC Cancer 8:312. 2008
    ....
  31. doi request reprint Prognostic evaluation of tumour type and other histopathological characteristics in advanced epithelial ovarian cancer, treated with surgery and paclitaxel/carboplatin chemotherapy: cell type is the most useful prognostic factor
    A Bamias
    Dept of Clinical Therapeutics, Medical School, University of Athens, Athens, Greece
    Eur J Cancer 48:1476-83. 2012
    ..Ovarian carcinomas have been classified into types I and II according to the hypothesised mode of carcinogenesis and molecular characteristics. The prognostic significance of this classification has not been studied...
  32. doi request reprint Needle tract seeding after vacuum-assisted breast biopsy
    N V Michalopoulos
    Breast Unit, First Department of Propaedeutic Surgery, Hippokratio Hospital, School of Medicine, University of Athens, Athens, Greece
    Acta Radiol 49:267-70. 2008
    ..A matter of substantial concern regarding all needle biopsy techniques is seeding along the biopsy needle tract...
  33. ncbi request reprint Management of advanced stage uterine sarcomas: a bone of contention
    F Zagouri
    Department of Clinical Therapeutics, Alexandra Hospital, University of Athens School of Medicine, Athens, Greece
    Eur J Gynaecol Oncol 30:483-92. 2009
    ..Considering the poor overall survival in uterine sarcomas, the need for new therapeutic agents is critical. New drugs with possible activity in uterine sarcomas include trabectedin, temozolomide, liposomal doxorubicin and gemcitabine...
  34. ncbi request reprint Use of fogarty catheter to limit hemorrhage and hematoma after vacuum-assisted breast biopsy
    G C Zografos
    Breast Unit, First Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens, Athens, Greece
    Acta Radiol 49:752-4. 2008
    ..At clinical examination 9 days after VABB, no hematoma was present. The use of a Fogarty catheter seems capable of limiting any severe bleeding after VABB and may also possibly prevent subsequent hematoma formation...
  35. ncbi request reprint Estimation of maspin's subcellular localization in invasive ductal breast cancer via light microscopy and computerized image analysis: a comparative study
    M Panou
    1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
    J BUON 18:342-51. 2013
    ..We also examined correlations between maspin expression and several clinicopathological parameters...
  36. doi request reprint Prognostic factors for early-stage epithelial ovarian cancer, treated with adjuvant carboplatin/paclitaxel chemotherapy: a single institution experience
    A Bamias
    Department of Clinical Therapeutics, University of Athens, Athens, Greece
    Gynecol Oncol 123:37-42. 2011
    ..Early-stage epithelial ovarian cancer represents a prognostically heterogenous group. We studied prognostic factors in patients treated with adjuvant paclitaxel/carboplatin chemotherapy...
  37. ncbi request reprint Imprint cytology of vacuum-assisted breast biopsy specimens: a rapid diagnostic tool in non-palpable solid lesions
    V Oikonomou
    Department of Cytology, Hippokratio Hospital, Athens, Greece
    Cytopathology 19:311-5. 2008
    ..This study aims to assess the validity of imprint cytology for the pre-operative diagnosis of non-palpable mammographic solid lesions excised by vacuum-assisted breast biopsy (VABB)...
  38. pmc High MET expression is an adverse prognostic factor in patients with triple-negative breast cancer
    F Zagouri
    Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria
    Br J Cancer 108:1100-5. 2013
    ..The purpose of our study was to determine the prognostic value of tumour MET expression levels in patients with triple-negative breast cancer (TNBC), in order to strengthen the rationale for targeted therapy of TNBC using MET inhibitors...
  39. ncbi request reprint Tumor dissemination after laparoscopic surgery for an unsuspected endometrial stromal tumor
    K Pavlakis
    Department of Pathology, Athens University Medical School, Athens, Greece
    Eur J Gynaecol Oncol 32:362-3. 2011
    ..Experimental data suggest that the risk of tumor dissemination in the non traumatized peritoneum may be higher after pneumoperitoneum than after laparotomy, and they also show the importance of the surgeon's experience and technique...
  40. ncbi request reprint Cholangiocarcinoma: principles and current trends
    George N Zografos
    Third Department of Surgery, Athens General Hospital, Athens, Greece
    Hepatobiliary Pancreat Dis Int 10:10-20. 2011
    ..It is a rare malignancy associated with poor prognosis...
  41. doi request reprint Lobular neoplasia in vacuum-assisted breast biopsy: extended protocols and underestimation
    George C Zografos
    AJR Am J Roentgenol 190:W272. 2008
  42. ncbi request reprint Vacuum-assisted breast biopsy: A role also on palpable lesions?
    Flora Zagouri
    Med Hypotheses 70:198-9. 2008
  43. ncbi request reprint Minimizing underestimation rate of microcalcifications excised via vacuum-assisted breast biopsy: a blind study
    George C Zografos
    1st Department of Surgery, School of Medecine, Athens University, Ampelokipi, Athens 11521, Greece
    Breast Cancer Res Treat 109:397-402. 2008
    ..The main disadvantage of Vacuum Assisted Breast Biopsy (VABB) is the probability of underestimating atypical ductal hyperplasia (ADH) and ductal carcinoma in situ (DCIS). This study evaluates a modified way of performing VABB...
  44. ncbi request reprint Open breast biopsy under local anesthesia: a well-tolerated method
    George C Zografos
    Pain Pract 7:288-9. 2007
  45. ncbi request reprint Pain in different methods of breast biopsy: emphasis on vacuum-assisted breast biopsy
    Flora Zagouri
    Breast Unit, First Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens, Greece
    Breast 17:71-5. 2008
    ..In conclusion, although VABB is less painful than hook-wire, the pain experienced in VABB is significant; however, it can be attenuated by a second dose of lidocaine...
  46. ncbi request reprint Immunohistochemical expression of estrogen receptors alpha and beta in lobular neoplasia
    Aphrodite Nonni
    1st Department of Pathology, Medical School, University of Athens, Athens, Greece
    Virchows Arch 451:893-7. 2007
    ..5044, p = 0.001). In conclusion, upregulation of ER-alpha and downregulation of ER-beta may represent two discrete molecular events in LN pathogenesis. Of notice, a mutually limiting interaction may exist between the two events...
  47. ncbi request reprint Atypical ductal hyperplasia: a way to minimize underestimation in vacuum-assisted breast biopsy?
    George C Zografos
    Breast 17:6. 2008
  48. ncbi request reprint Lesions of "uncertain malignant potential" diagnosed by vacuum-assisted breast biopsy: an unclear management?
    George Zografos
    Ann Surg Oncol 15:2053-4; author reply 2055-6. 2008