Research Topics
Species | - YasminSummaryCountry: UK Publications
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Publications
Determinants of arterial stiffness in offspring of families with essential hypertension- Yasmin
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
Am J Hypertens 17:292-8. 2004..We investigated whether arterial stiffness measured as augmentation index and pulse wave velocity is increased in offspring of families with essential hypertension, and whether stiffness is related to various biochemical markers...
The impact of cardiovascular risk factors on aortic stiffness and wave reflections depends on age: the Anglo-Cardiff Collaborative Trial (ACCT III)Carmel M McEniery
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Box 110, Hills Rd, Cambridge CB2 0QQ, UK
Hypertension 56:591-7. 2010..Additional studies are required to assess the impact of these arterial measures on cardiovascular outcome within a single population...
Aortic calcification is associated with aortic stiffness and isolated systolic hypertension in healthy individualsCarmel M McEniery
Clinical Pharmacology Unit, Box 100, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 0QQ, United Kingdom
Hypertension 53:524-31. 2009..These data suggest that calcification may be important in the process of aortic stiffening and the development of ISH. Calcification may underlie treatment resistance in ISH, and anticalcification strategies may present a novel therapy...
Variation in the human matrix metalloproteinase-9 gene is associated with arterial stiffness in healthy individuals- Yasmin
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Box 110, Cambridge CB2 2QQ, UK
Arterioscler Thromb Vasc Biol 26:1799-805. 2006..Therefore, we investigated the influence of known MMP-9 (-1562C>T, R279Q) polymorphisms on arterial stiffness in a large cohort of healthy individuals (n=865)...
The impact of birth weight on blood pressure and arterial stiffness in later life: the Enigma StudyKaren L Miles
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
J Hypertens 29:2324-31. 2011..However, the relationship between birth weight, blood pressure, arterial stiffness and wave reflections as putative mechanisms is controversial...
Central pressure: variability and impact of cardiovascular risk factors: the Anglo-Cardiff Collaborative Trial IICarmel M McEniery
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital Box 110, Cambridge CB2 2QQ, United Kingdom
Hypertension 51:1476-82. 2008..However, assessment of central pressure may improve the identification and management of patients with elevated cardiovascular risk...
Endothelial function is associated with pulse pressure, pulse wave velocity, and augmentation index in healthy humansCarmel M McEniery
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
Hypertension 48:602-8. 2006..001), which remained independent after adjusting for confounding factors. In healthy individuals, a decline in endothelial function is associated with increased large artery stiffness, wave reflections, and central pulse pressure...
Increased stroke volume and aortic stiffness contribute to isolated systolic hypertension in young adultsCarmel M McEniery
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
Hypertension 46:221-6. 2005..Long-term follow-up of these individuals is now required to determine whether they are at increased risk compared with age-matched normotensive individuals...
Use of the oral contraceptive pill is associated with increased large artery stiffness in young women: the ENIGMA studyStacey S Hickson
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
J Hypertens 29:1155-9. 2011..The aim of this study was to determine the relationship between use of the OCP and aortic stiffness and wave reflections in a young, healthy cohort of women...
A comparison of atenolol and nebivolol in isolated systolic hypertensionZahid Dhakam
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge, CB2 2QQ, UK
J Hypertens 26:351-6. 2008..The aim of the present study was to test this in a double-blind, randomized, cross-over study, in a cohort of subjects with isolated systolic hypertension...
Rheumatoid arthritis is associated with increased aortic pulse-wave velocity, which is reduced by anti-tumor necrosis factor-alpha therapyKaisa M Maki-Petaja
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Box 110, Cambridge CB2 2QQ, United Kingdom
Circulation 114:1185-92. 2006..In addition, we tested the hypothesis that aortic stiffness could be reduced with anti-tumor necrosis factor-alpha (TNF-alpha) therapy...
The accuracy of central SBP determined from the second systolic peak of the peripheral pressure waveformStacey S Hickson
University of Cambridge, Addenbrooke s Hospital, UK
J Hypertens 27:1784-8. 2009..We also compared pSBP(2) with the true cSBP measured by cardiac catheterization [invasively measured cSBP (cSBPi)]...
Genetics of arterial structure and function: towards new biomarkers for aortic stiffness?- Yasmin
Clinical Pharmacology Unit, Department of Medicine, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
Clin Sci (Lond) 114:661-77. 2008....
Normal vascular aging: differential effects on wave reflection and aortic pulse wave velocity: the Anglo-Cardiff Collaborative Trial (ACCT)Carmel M McEniery
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
J Am Coll Cardiol 46:1753-60. 2005....
Genetic variation in fibrillin-1 gene is not associated with arterial stiffness in apparently healthy individuals- Yasmin
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
J Hypertens 24:499-502. 2006..The aim of this study was to investigate the possible influence of the common FBN-1 genotypes on arterial stiffness in a large cohort of healthy individuals...
Matrix metalloproteinase-9 (MMP-9), MMP-2, and serum elastase activity are associated with systolic hypertension and arterial stiffness- Yasmin
Clinical Pharmacology Unit, University of Cambridge Addenbrooke s Hospital Cambridge, United Kingdom
Arterioscler Thromb Vasc Biol 25:372. 2005..We hypothesized that elastase activity would be related to arterial stiffness and tested this using isolated systolic hypertension (ISH) as a model of stiffening and separately in a large cohort of healthy individuals...
