Jack W Winter

Summary

Country: UK

Publications

  1. ncbi Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease
    J Winter
    Gastroenterology Unit, Gartnavel General Hospital, Glasgow, Scotland
    Aliment Pharmacol Ther 20:593-9. 2004
  2. ncbi Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease
    J W Winter
    Gastroenterology Unit, Gartnavel General Hospital, Glasgow, UK
    Aliment Pharmacol Ther 25:1069-77. 2007
  3. ncbi N-nitrosamine generation from ingested nitrate via nitric oxide in subjects with and without gastroesophageal reflux
    Jack W Winter
    Division of Medicine, Western Infirmary, Glasgow, United Kingdom
    Gastroenterology 133:164-74. 2007
  4. ncbi The nonerosive reflux disease-gastroesophageal reflux disease controversy
    Jack W Winter
    Glasgow Royal Infirmary, Glasgow, UK
    Curr Opin Gastroenterol 24:509-15. 2008

Detail Information

Publications4

  1. ncbi Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease
    J Winter
    Gastroenterology Unit, Gartnavel General Hospital, Glasgow, Scotland
    Aliment Pharmacol Ther 20:593-9. 2004
    ..Its use is limited by its side-effect profile. Marrow toxicity occurs in approximately 3.2% of patients and is known to be associated with diminished thiopurine methyltransferase enzyme activity resulting from genetic polymorphisms...
  2. ncbi Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease
    J W Winter
    Gastroenterology Unit, Gartnavel General Hospital, Glasgow, UK
    Aliment Pharmacol Ther 25:1069-77. 2007
    ..It has been proposed that pretreatment assessment of TPMT status reduces the incidence of toxicity and is cost-effective...
  3. ncbi N-nitrosamine generation from ingested nitrate via nitric oxide in subjects with and without gastroesophageal reflux
    Jack W Winter
    Division of Medicine, Western Infirmary, Glasgow, United Kingdom
    Gastroenterology 133:164-74. 2007
    ..We aimed to ascertain if luminal nitric oxide exerts nitrosative stress in the human upper gastrointestinal tract, and to assess the influence of acid reflux on this phenomenon...
  4. ncbi The nonerosive reflux disease-gastroesophageal reflux disease controversy
    Jack W Winter
    Glasgow Royal Infirmary, Glasgow, UK
    Curr Opin Gastroenterol 24:509-15. 2008
    ..To analyse the concept of nonerosive reflux disease (NERD), examining its evolving definition and its relationship to reflux disease and functional gastrointestinal disorders...