Research Topics
Genomes and GenesSpecies | Mary WhiteSummaryCountry: UK Publications
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Publications
Transforming growth factor beta-1 and interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infectionMary White
Department of Anaesthesia, St James Hospital, Dublin 8, Ireland Institute of Molecular Medicine, Trinity College Dublin, Ireland
Cytokine 50:322-7. 2010..We investigated the hypothesis that the onset of sepsis is related to differential TGFbeta-1 and IL-17 gene expression...
Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expressionMary White
Department of Anaesthesia and Critical Care Medicine, St James Hospital, and Deparmtent of Clinical Medicine, Trinity College Dublin, Dublin 8, Ireland
Chest 139:626-32. 2011..The secondary end point was to identify whether alteration in gene expression preceded the clinical onset of infection...
Post-operative infection and sepsis in humans is associated with deficient gene expression of γc cytokines and their apoptosis mediatorsMary White
Dept of Anaesthesia and Intensive Care Medicine, St James Hospital, James Street, Dublin 08, Ireland
Crit Care 15:R158. 2011..Lymphocyte homeostasis is dependent on the γc cytokines. We hypothesised that sepsis in humans is associated with differential gene expression of the γc cytokines and their associated apoptosis mediators...
The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expressionMichael J O'Dwyer
Department of Anaesthesia, St James s Hospital, Dublin, Ireland
Intensive Care Med 34:683-91. 2008..As alternative regulators of IFNgamma may be of greater importance in human sepsis, we investigated the hypothesis that the development of severe sepsis is related to variations in IL-18, IL-23 and IL-27 gene expression...
The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expressionMichael J O'Dwyer
Department of Anaesthesia, St James s Hospital, Dublin, Ireland
Shock 26:544-50. 2006..Quantitative real-time polymerase chain reaction can be used to predict infection outcome in clinically relevant situations where enzyme-linked immunosorbent assay testing has proved disappointing...
Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responsesMatthew W Lawless
Hepatology Research Division and Department of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St, James Hospital, Dublin, Ireland
BMC Cell Biol 8:30. 2007..In this context, we sought to identify ER stress signals associated with mutant C282Y HFE protein expression, which may have a role in the molecular pathogenesis of HH...
