Research Topics
Genomes and Genes | Corin YeatsSummaryAffiliation: Wellcome Trust Genome Campus Country: UK Publications
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Detail Information
Publications
The PASTA domain: a beta-lactam-binding domainCorin Yeats
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK CB10 1SA
Trends Biochem Sci 27:438. 2002..We postulate that PknB-like kinases are key regulators of cell-wall biosynthesis. The essential function of these enzymes suggests an additional pathway for the action of beta-lactam antibiotics...
The BON domain: a putative membrane-binding domainCorin Yeats
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK CB10 1SA
Trends Biochem Sci 28:352-5. 2003
The PepSY domain: a regulator of peptidase activity in the microbial environment?Corin Yeats
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK
Trends Biochem Sci 29:169-72. 2004
New knowledge from old: in silico discovery of novel protein domains in Streptomyces coelicolorCorin Yeats
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK
BMC Microbiol 3:3. 2003..We sought to expand our understanding of this organism at the molecular level through identification and annotation of novel protein domains. Protein domains are the evolutionary conserved units from which proteins are formed...
InterPro: the integrative protein signature databaseSarah Hunter
EMBL Outstation European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Nucleic Acids Res 37:D211-5. 2009..InterPro data may be accessed either via the web address above, via web services, by downloading files by anonymous FTP or by using the InterProScan search software (http://www.ebi.ac.uk/Tools/InterProScan/)...
The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variationNicholas R Thomson
The Pathogen Sequencing Unit, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
Genome Res 15:629-40. 2005....
The G5 domain: a potential N-acetylglucosamine recognition domain involved in biofilm formationAlex Bateman
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Bioinformatics 21:1301-3. 2005..A common feature of the proteins containing G5 domains is N-acetylglucosamine binding, and we attribute this function to the G5 domain. CONTACT: agb@sanger.ac.uk...
InterPro in 2011: new developments in the family and domain prediction databaseSarah Hunter
EMBL Outstation European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SD Cambridge, UK
Nucleic Acids Res 40:D306-12. 2012..Herein we give an overview of new developments in the database and its associated software since 2009, including updates to database content, curation processes and Web and programmatic interfaces...
New developments in the InterPro databaseNicola J Mulder
EMBL Outstation European Bioinformatics Institute Hinxton, Cambridge, UK
Nucleic Acids Res 35:D224-8. 2007..ebi.ac.uk/interpro), and for download by anonymous FTP (ftp://ftp.ebi.ac.uk/pub/databases/interpro). The InterProScan search tool is now also available via a web service at http://www.ebi.ac.uk/Tools/webservices/WSInterProScan.html...
The Pfam protein families databaseAlex Bateman
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Nucleic Acids Res 32:D138-41. 2004..Pfam is available on the web in the UK (http://www.sanger.ac.uk/Software/Pfam/), the USA (http://pfam.wustl.edu/), France (http://pfam.jouy.inra.fr/) and Sweden (http://Pfam.cgb.ki.se/)...
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomalleiMatthew T G Holden
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
Proc Natl Acad Sci U S A 101:14240-5. 2004..mallei. We propose that variable horizontal gene acquisition by B. pseudomallei is an important feature of recent genetic evolution and that this has resulted in a genetically diverse pathogenic species...
