- Detailed molecular characterisation of acute myeloid leukaemia with a normal karyotype using targeted DNA captureN Conte
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Leukemia 27:1820-5. 2013..This methodology reliably detects sequence and copy number mutations, and can thus greatly facilitate the classification, clinical research, diagnosis and management of AML-NK. ..
- Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in miceGeorge S Vassiliou
Mouse Genomics Team, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Nat Genet 43:470-5. 2011..We also identified recurrent integrations in known and newly discovered leukemia genes including Nf1, Bach2, Dleu2 and Nup98. Our results provide new pathogenetic insights and identify possible therapeutic targets in NPM1c+ AML...