Research Topics
| Juan M VaquerizasSummaryAffiliation: Wellcome Trust Genome Campus Country: UK Publications
| Collaborators |
Detail Information
Publications
A census of human transcription factors: function, expression and evolutionJuan M Vaquerizas
EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK
Nat Rev Genet 10:252-63. 2009..Much remains to be explored, but this study provides a solid foundation for future investigations to elucidate regulatory mechanisms underlying diverse mammalian biological processes...
Large-scale nuclear architecture and transcriptional controlJuan M Vaquerizas
EMBL European Bioinformatics Institute, CB10 1SD, Cambridge, UK
Subcell Biochem 52:279-95. 2011..Here, we summarise the different levels of chromatin organisation in the nucleus and discuss current efforts into characterising the mechanisms that govern it...
How do you find transcription factors? Computational approaches to compile and annotate repertoires of regulators for any genomeJuan M Vaquerizas
EMBL European Bioinformatics Institute, Cambridge, UK
Methods Mol Biol 786:3-19. 2012..These analysis methods provide a solid foundation for further investigations of the transcriptional regulatory system...
SpeCond: a method to detect condition-specific gene expressionFlorence M G Cavalli
EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SD, UK
Genome Biol 12:R101. 2011..An implementation of SpeCond is freely available as a Bioconductor package at http://www.bioconductor.org/packages/release/bioc/html/SpeCond.html...
m:Explorer: multinomial regression models reveal positive and negative regulators of longevity in yeast quiescenceJüri Reimand
EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK
Genome Biol 13:R55. 2012..m:Explorer (http://biit.cs.ut.ee/mexplorer/) is instrumental in interrogating eukaryotic regulatory systems using heterogeneous data...
Comprehensive reanalysis of transcription factor knockout expression data in Saccharomyces cerevisiae reveals many new targetsJüri Reimand
EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK
Nucleic Acids Res 38:4768-77. 2010..compendium. The dataset is available from ArrayExpress (accession: E-MTAB-109) and it will be invaluable to any scientist interested in the yeast transcriptional regulatory system...
