Michael Stratton

Summary

Affiliation: Wellcome Trust Genome Campus
Country: UK

Publications

  1. ncbi Genome resequencing and genetic variation
    Michael Stratton
    Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nat Biotechnol 26:65-6. 2008
  2. ncbi Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer
    Elizabeth P Murchison
    Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, UK
    Cell 148:780-91. 2012
  3. ncbi Somatic structural rearrangements in genetically engineered mouse mammary tumors
    Ignacio Varela
    Wellcome Trust Sanger Institute, Hinxton, Cambridge CB101SA, UK
    Genome Biol 11:R100. 2010
  4. ncbi RNA editing of human microRNAs
    Matthew J Blow
    Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
    Genome Biol 7:R27. 2006
  5. ncbi Mutation analysis of 24 known cancer genes in the NCI-60 cell line set
    Ogechi N Ikediobi
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom
    Mol Cancer Ther 5:2606-12. 2006
  6. ncbi The cancer genome
    Michael R Stratton
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nature 458:719-24. 2009
  7. ncbi Exploring the genomes of cancer cells: progress and promise
    Michael R Stratton
    Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
    Science 331:1553-8. 2011
  8. ncbi Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization
    Goran Jonsson
    Department of Oncology, University Hospital, Lund, Sweden
    Cancer Res 65:7612-21. 2005

Collaborators

  • P Andrew Futreal
  • Richard Wooster
  • Stijn van Dongen
  • Anton J Enright
  • David Richardson
  • Peter J Campbell
  • Thomas Santarius
  • John N Weinstein
  • David Jones
  • Tara L Naylor
  • Markus Ringner
  • Elizabeth P Murchison
  • Ignacio Varela
  • Keiran Raine
  • Russell J Grocock
  • Ogechi N Ikediobi
  • Matthew J Blow
  • Ed Dicks
  • Goran Jonsson
  • Gary Schroth
  • Sergii Ivakhno
  • Kevin Hall
  • Richard Shaw
  • Ole B Schulz-Trieglaff
  • Alexandre Kreiss
  • Zoya Kingsbury
  • Stephen M J Searle
  • Zhihao Ding
  • Anthony T Papenfuss
  • Mark Kowarsky
  • Wendy Wong
  • Shujun Luo
  • Philip Tedder
  • Markus J Bauer
  • Geoffrey Smith
  • Bronwen Aken
  • Ludmil B Alexandrov
  • Carolyn Tregidgo
  • Nigel P Carter
  • Zhi Ping Feng
  • Caitlin Stewart
  • R Keira Cheetham
  • David C Wedge
  • Jennifer Becq
  • William Cheng
  • Amber Alsop
  • Lisa Murray
  • Thomas R Connor
  • Zemin Ning
  • Irina Khrebtukova
  • Dirk J Evers
  • Bee Ling Ng
  • Simon White
  • Isabelle Rasolonjatovo
  • Matthew Hims
  • Yong Gu
  • John Marshall
  • Anthony J Cox
  • Simon R Harris
  • Fengtang Yang
  • Gregory M Woods
  • Sean Humphray
  • Anne Maree Pearse
  • David R Bentley
  • Albert J Vilella
  • David J McBride
  • Niall Gormley
  • Beiyuan Fu
  • Graham R Bignell
  • David J Adams
  • Eva Schut
  • Christiaan Klijn
  • Lodewyk Fa Wessels
  • Lucy Stebbings
  • Danushka Galappaththige
  • Hanneke van der Gulden
  • Sjoerd Klarenbeek
  • Laura J Mudie
  • Jos Jonkers
  • Phillip J Stephens
  • Vivienne Kosmidou
  • William Reinhold
  • Jennifer Varian
  • Tim Avis
  • Janet Perry
  • Philip Stephens
  • Andrew Menzies
  • Jonathan Hinton
  • Chris Hunter
  • Simon Forbes

Detail Information

Publications8

  1. ncbi Genome resequencing and genetic variation
    Michael Stratton
    Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nat Biotechnol 26:65-6. 2008
  2. ncbi Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer
    Elizabeth P Murchison
    Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, UK
    Cell 148:780-91. 2012
    ....
  3. ncbi Somatic structural rearrangements in genetically engineered mouse mammary tumors
    Ignacio Varela
    Wellcome Trust Sanger Institute, Hinxton, Cambridge CB101SA, UK
    Genome Biol 11:R100. 2010
    ..These were models of Trp53-mutated breast cancer, Brca1- and Brca2-associated hereditary breast cancer, and E-cadherin (Cdh1) mutated lobular breast cancer...
  4. ncbi RNA editing of human microRNAs
    Matthew J Blow
    Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
    Genome Biol 7:R27. 2006
    ..These miRNAs may have been annotated to the wrong genomic strand. CONCLUSION: Our results indicate that RNA editing increases the diversity of miRNAs and their targets, and hence may modulate miRNA function...
  5. ncbi Mutation analysis of 24 known cancer genes in the NCI-60 cell line set
    Ogechi N Ikediobi
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom
    Mol Cancer Ther 5:2606-12. 2006
    ....
  6. ncbi The cancer genome
    Michael R Stratton
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nature 458:719-24. 2009
    ..These studies will provide us with a detailed and comprehensive perspective on how individual cancers have developed...
  7. ncbi Exploring the genomes of cancer cells: progress and promise
    Michael R Stratton
    Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
    Science 331:1553-8. 2011
    ..Here, I provide an overview of what these efforts have revealed to date about the origin and behavioral features of cancer cells and how this genomic information is being exploited to improve diagnosis and therapy of the disease...
  8. ncbi Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization
    Goran Jonsson
    Department of Oncology, University Hospital, Lund, Sweden
    Cancer Res 65:7612-21. 2005
    ..00005, respectively). Further validation may prove this tumor classifier to be useful for selecting familial breast cancer cases for further mutation screening, particularly, as these data can be obtained using archival tissue...