Research Topics
| Ugis SarkansSummaryAffiliation: Wellcome Trust Genome Campus Country: UK Publications
| Collaborators
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Detail Information
Publications
PASSIM--an open source software system for managing information in biomedical studiesJuris Viksna
Institute of Mathematics and Computer Science, Riga, University of Latvia, Latvia
BMC Bioinformatics 8:52. 2007..There is a clear need for lightweight open source systems for patient and sample information management...
The ArrayExpress gene expression database: a software engineering and implementation perspectiveUgis Sarkans
EMBL Outstation Hinxton, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
Bioinformatics 21:1495-501. 2005..Our experience will be both relevant and useful for most bioinformaticians involved in developing information systems for a wide range of high-throughput technologies...
ArrayExpress: a public database of gene expression data at EBIPhilippe Rocca-Serra
EMBL Outstation-Hinxton, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, United Kingdom
C R Biol 326:1075-8. 2003..Data retrieval is performed through a dedicated web interface. Relevant results may be exported to ExpressionProfiler, the EBI based expression analysis tool available online (http://www.ebi.ac.uk/arrayexpress)...
ArrayExpress update--an archive of microarray and high-throughput sequencing-based functional genomics experimentsHelen Parkinson
Functional Genomics Team, EMBL EBI, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK
Nucleic Acids Res 39:D1002-4. 2011..Advanced queries provided via ontology enabled interfaces include queries based on technology and sample attributes such as disease, cell types and anatomy...
Plant-based microarray data at the European Bioinformatics Institute. Introducing AtMIAMExpress, a submission tool for Arabidopsis gene expression data to ArrayExpressGaurab Mukherjee
EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Plant Physiol 139:632-6. 2005..The AtMIAMExpress submission tool is available at http://www.ebi.ac.uk/at-miamexpress/. The software is open source and is available from http://sourceforge.net/projects/miamexpress/. For information, contact miamexpress@ebi.ac.uk...
ArrayExpress update--from an archive of functional genomics experiments to the atlas of gene expressionHelen Parkinson
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
Nucleic Acids Res 37:D868-72. 2009..In this update, we describe the ArrayExpress developments over the last two years...
ArrayExpress--a public repository for microarray gene expression data at the EBIAlvis Brazma
European Bioinformatics Institute, EMBL EBI, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK
Nucleic Acids Res 31:68-71. 2003..With an increasing number of organisations adopting MAGE-ML standard, the volume of submissions to ArrayExpress is increasing rapidly. The database can be accessed at http://www.ebi.ac.uk/arrayexpress...
Data storage and analysis in ArrayExpress and Expression ProfilerGabriella Rustici
European Bioinformatics Institute EMBL EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
Curr Protoc Bioinformatics . 2008....
ArrayExpress update--trends in database growth and links to data analysis toolsGabriella Rustici
Functional Genomics Team, EMBL EBI, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK
Nucleic Acids Res 41:D987-90. 2013..Additionally, R objects, for microarray data, and binary alignment format files, for sequencing data, have been generated for a significant proportion of ArrayExpress data...
A simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TABTim F Rayner
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
BMC Bioinformatics 7:489. 2006..However, the complexity of the MAGE-ML format has made its use impractical for laboratories lacking dedicated bioinformatics support...
The BioSample Database (BioSD) at the European Bioinformatics InstituteMikhail Gostev
EMBL EBI, The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
Nucleic Acids Res 40:D64-70. 2012..A simple tab-delimited format facilitates submissions of sample information to the database, initially via email to biosamples@ebi.ac.uk...
Data storage and analysis in ArrayExpressAlvis Brazma
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Methods Enzymol 411:370-86. 2006..This chapter describes all major ArrayExpress components from the user perspective: how to submit to, retrieve from, and analyze data in ArrayExpress...
Microarray data representation, annotation and storageAlvis Brazma
EMBL Outstation Hinxton, European Bioinformatics Institute, Cambridge, UK
Adv Biochem Eng Biotechnol 77:113-39. 2002..We describe two data models--a simpler one called ArrayExpressB and the complete model ArrayExpressC, and discuss some implementation issues. For latest developments see http: wwwebi.ac.uk/arrayexpress..
The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction dataHenning Hermjakob
European Bioinformatics Institute, EBI Hinxton, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Nat Biotechnol 22:177-83. 2004....
A System for Information Management in BioMedical Studies--SIMBioMSMaria Krestyaninova
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB101SD, UK
Bioinformatics 25:2768-9. 2009..Protocols for transferring data to durable archives at the European Bioinformatics Institute have been implemented. AVAILABILITY: The source code, documentation and initialization scripts are available at http://simbioms.org...
graph2tab, a library to convert experimental workflow graphs into tabular formatsMarco Brandizi
European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK
Bioinformatics 28:1665-7. 2012..The problem of converting the graph of an experimental workflow into a table-based representation occurs in many such formats and is not easy to solve...
Standards for systems biologyAlvis Brazma
European Bioinformatics Institute, EMBL EBI, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK
Nat Rev Genet 7:593-605. 2006..Why are some standards more successful than others, what are the prerequisites for a standard to succeed and what are the possible pitfalls?..
Expression Profiler: next generation--an online platform for analysis of microarray dataMisha Kapushesky
European Bioinformatics Institute, United Kingdom
Nucleic Acids Res 32:W465-70. 2004..EP:NG is an open-source project, encouraging broad distribution and further extensions from the scientific community...
Wrestling with SUMO and bio-ontologiesChristian Stoeckert
Nat Biotechnol 24:21-2; author reply 23. 2006
The Functional Genomics Experiment model (FuGE): an extensible framework for standards in functional genomicsAndrew R Jones
School of Computer Science, University of Manchester, Oxford Road, Manchester, M13 9PL, UK
Nat Biotechnol 25:1127-33. 2007..Such advances are important for transparent data management and mining in functional genomics and systems biology...
Design and implementation of microarray gene expression markup language (MAGE-ML)Paul T Spellman
Department of Cell and Molecular Biology, University of California at Berkeley, Berkeley, CA 94720 3206, USA
Genome Biol 3:RESEARCH0046. 2002..Only when data can be easily exchanged will the entire biological community be able to derive the full benefit from such microarray studies...
