Thomas Santarius

Summary

Affiliation: Wellcome Trust Genome Campus
Country: UK

Publications

  1. pmc GLO1-A novel amplified gene in human cancer
    Thomas Santarius
    Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK
    Genes Chromosomes Cancer 49:711-25. 2010
  2. pmc PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data
    Chris D Greenman
    Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Biostatistics 11:164-75. 2010
  3. pmc Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
    Peter J Campbell
    Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK
    Nat Genet 40:722-9. 2008
  4. doi A census of amplified and overexpressed human cancer genes
    Thomas Santarius
    The Wellcome Trust Sanger Centre, Wellcome Trust Genome Campus Hinxton, Cambridge, UK
    Nat Rev Cancer 10:59-64. 2010
  5. pmc Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution
    Graham R Bignell
    Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, United Kingdom
    Genome Res 17:1296-303. 2007
  6. pmc Mutation analysis of 24 known cancer genes in the NCI-60 cell line set
    Ogechi N Ikediobi
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom
    Mol Cancer Ther 5:2606-12. 2006

Collaborators

  • P Andrew Futreal
  • Chris D Greenman
  • Heng Li
  • David Richardson
  • Peter J Campbell
  • Daniel J Turner
  • Lina Chen
  • Paul J Thornalley
  • Richard Wooster
  • John N Weinstein
  • David Jones
  • Graham R Bignell
  • Janet Perry
  • Andrew Menzies
  • Sarah Edkins
  • Michael R Stratton
  • Ogechi N Ikediobi
  • Michael Quail
  • Jessica C M Pole
  • Lucy Matthews
  • Erin Pleasance
  • Paul A W Edwards
  • Bob Plumb
  • Adam P Butler
  • Sheila Taylor
  • Jane Rogers
  • Kirsten McLay
  • Katy Hills
  • Alex Small
  • Jonathan Hinton
  • William Reinhold
  • Graham Bignell
  • Rachel Harrison
  • Jon Teague
  • Andy Jenkinson
  • Chris Hunter
  • Andy Yates
  • Sara Widaa
  • Sarah O'Meara
  • Helen Davies
  • Rebecca Shepherd
  • Simon Forbes
  • Raffaella Smith
  • Syd Barthorpe
  • Tony Webb
  • Tatiana Mironenko
  • Ed Dicks
  • Calli Tofts
  • Kelly Halliday
  • Tim Avis
  • Lisa Brackenbury
  • Gemma Buck
  • Kristian Gray
  • Claire Stevens
  • Philip Stephens
  • Jody Clements
  • Jennifer Varian
  • Jennifer Cole
  • Vivienne Kosmidou
  • Richard Lugg
  • Adrian Parker
  • Sofie West
  • Keiran Raine
  • Adam Butler
  • Helen Solomon

Detail Information

Publications6

  1. pmc GLO1-A novel amplified gene in human cancer
    Thomas Santarius
    Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK
    Genes Chromosomes Cancer 49:711-25. 2010
    ..Collectively the results indicate that GLO1 is at least one of the targets of gene amplification on 6p21.2 and may represent a useful target for therapy in cancers with GLO1 amplification...
  2. pmc PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data
    Chris D Greenman
    Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Biostatistics 11:164-75. 2010
    ..These methods are exemplified with affymetrix genome-wide SNP6.0 data from 755 cancer cell lines, enabling inference upon a number of features of biological interest. These data and the coded algorithm are freely available for download...
  3. pmc Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
    Peter J Campbell
    Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK
    Nat Genet 40:722-9. 2008
    ..The results demonstrate the feasibility of systematic, genome-wide characterization of rearrangements in complex human cancer genomes, raising the prospect of a new harvest of genes associated with cancer using this strategy...
  4. doi A census of amplified and overexpressed human cancer genes
    Thomas Santarius
    The Wellcome Trust Sanger Centre, Wellcome Trust Genome Campus Hinxton, Cambridge, UK
    Nat Rev Cancer 10:59-64. 2010
    ..In a census of the published literature we have identified 77 genes for which there is good evidence of involvement in the development of human cancer...
  5. pmc Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution
    Graham R Bignell
    Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, United Kingdom
    Genome Res 17:1296-303. 2007
    ....
  6. pmc Mutation analysis of 24 known cancer genes in the NCI-60 cell line set
    Ogechi N Ikediobi
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom
    Mol Cancer Ther 5:2606-12. 2006
    ....