Haydn M Prosser

Summary

Affiliation: Wellcome Trust Genome Campus
Country: UK

Publications

  1. ncbi A resource of vectors and ES cells for targeted deletion of microRNAs in mice
    Haydn M Prosser
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
    Nat Biotechnol 29:840-5. 2011
  2. ncbi Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereocilia
    Haydn M Prosser
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
    Mol Cell Biol 28:1702-12. 2008
  3. ncbi Olfactory bulb hypoplasia in Prokr2 null mice stems from defective neuronal progenitor migration and differentiation
    Haydn M Prosser
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Eur J Neurosci 26:3339-44. 2007
  4. ncbi Agouti C57BL/6N embryonic stem cells for mouse genetic resources
    Stephen J Pettitt
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
    Nat Methods 6:493-5. 2009
  5. ncbi MyosinVIIa interacts with Twinfilin-2 at the tips of mechanosensory stereocilia in the inner ear
    Agnieszka K Rzadzinska
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
    PLoS ONE 4:e7097. 2009
  6. ncbi Prokineticin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei
    Haydn M Prosser
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
    Proc Natl Acad Sci U S A 104:648-53. 2007
  7. ncbi Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism
    Samuel G Jacobson
    Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA
    Hum Mol Genet 17:2405-15. 2008

Collaborators

Detail Information

Publications7

  1. ncbi A resource of vectors and ES cells for targeted deletion of microRNAs in mice
    Haydn M Prosser
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
    Nat Biotechnol 29:840-5. 2011
    ..This miRNA knockout (mirKO) resource can be searched electronically and is available from ES cell repositories for distribution to the scientific community...
  2. ncbi Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereocilia
    Haydn M Prosser
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
    Mol Cell Biol 28:1702-12. 2008
    ..Our results strongly suggest that myosin VIIa regulates the establishment of a setpoint for stereocilium heights, and this novel role may influence their normal staircase-like arrangement within a bundle...
  3. ncbi Olfactory bulb hypoplasia in Prokr2 null mice stems from defective neuronal progenitor migration and differentiation
    Haydn M Prosser
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Eur J Neurosci 26:3339-44. 2007
    ..Together, these findings suggest an important role for Prokr2 in OB neurogenesis...
  4. ncbi Agouti C57BL/6N embryonic stem cells for mouse genetic resources
    Stephen J Pettitt
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
    Nat Methods 6:493-5. 2009
    ..These cells provide a robust foundation for large-scale mouse knockout programs that aim to provide a public resource of targeted mutations in the C57BL/6 genetic background...
  5. ncbi MyosinVIIa interacts with Twinfilin-2 at the tips of mechanosensory stereocilia in the inner ear
    Agnieszka K Rzadzinska
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
    PLoS ONE 4:e7097. 2009
    ....
  6. ncbi Prokineticin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei
    Haydn M Prosser
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
    Proc Natl Acad Sci U S A 104:648-53. 2007
    ....
  7. ncbi Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism
    Samuel G Jacobson
    Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA 19104, USA
    Hum Mol Genet 17:2405-15. 2008
    ..The results point to the photoreceptor cell as the therapeutic target for USH treatment trials, such as MYO7A somatic gene replacement therapy...