Research Topics
| Alan M MosesSummaryAffiliation: Wellcome Trust Genome Campus Country: UK Publications
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Detail Information
Publications
Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sitesAlan M Moses
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1HH, United Kingdom
Proc Natl Acad Sci U S A 104:17713-8. 2007..Our results begin to explore the dynamics of regulatory evolution at the posttranslational level and show interesting similarities to recent observations of regulatory evolution at the level of transcription...
Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinaseAlan M Moses
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, UK
Genome Biol 8:R23. 2007..Our data suggest that regulatory modules may exist in protein sequence as clusters of short sequence motifs...
Inferring selection on amino acid preference in protein domainsAlan M Moses
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Mol Biol Evol 26:527-36. 2009..Finally, we analyze a model for selection on amino acid preferences in protein domains and find that it is consistent with the quantitative effects that we observe...
