Alan M Moses
Affiliation: Wellcome Trust Genome Campus
- Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sitesAlan M Moses
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1HH, United Kingdom
Proc Natl Acad Sci U S A 104:17713-8. 2007..Our results begin to explore the dynamics of regulatory evolution at the posttranslational level and show interesting similarities to recent observations of regulatory evolution at the level of transcription...
- Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinaseAlan M Moses
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, UK
Genome Biol 8:R23. 2007..Our data suggest that regulatory modules may exist in protein sequence as clusters of short sequence motifs...
- Inferring selection on amino acid preference in protein domainsAlan M Moses
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Mol Biol Evol 26:527-36. 2009..Finally, we analyze a model for selection on amino acid preferences in protein domains and find that it is consistent with the quantitative effects that we observe...