- Non-random mutation: the evolution of targeted hypermutation and hypomutationInigo Martincorena
Cancer Research UK London Research Institute, London, UK
Bioessays 35:123-30. 2013..Nevertheless, we show how an association of repair with transcription or chromatin-associated proteins could overcome the drift limit and lead to non-random hypomutation along the genome in most organisms...
- Evidence of non-random mutation rates suggests an evolutionary risk management strategyInigo Martincorena
EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SD, UK
Nature 485:95-8. 2012..The findings have important implications for our understanding of evolution and the control of mutations...