A Ivens

Summary

Affiliation: Wellcome Trust Genome Campus
Country: UK

Publications

  1. pmc Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum
    Gareth Bloomfield
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    Genome Biol 9:R75. 2008
  2. pmc Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa
    Carol J Loscher
    Smurfit Institute of Genetics, Trinity College Dublin, College Green, Dublin 2, Ireland
    Genome Biol 8:R248. 2007
  3. pmc Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common and specific effects from PAO1 and PA14 strains
    Sergio Carilla-Latorre
    Instituto de Investigaciones Biomedicas Alberto Sols, Universidad Autónoma de Madrid Consejo Superior de Investigaciones Científicas, Madrid, Spain
    BMC Microbiol 8:109. 2008
  4. pmc Gene copy number variation throughout the Plasmodium falciparum genome
    Ian H Cheeseman
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    BMC Genomics 10:353. 2009
  5. pmc Detection of genome-wide polymorphisms in the AT-rich Plasmodium falciparum genome using a high-density microarray
    Hongying Jiang
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    BMC Genomics 9:398. 2008
  6. pmc A software framework for microarray and gene expression object model (MAGE-OM) array design annotation
    Matloob Qureshi
    Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK
    BMC Genomics 9:133. 2008
  7. pmc Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium
    Alessio Sillo
    Department of Clinical and Biological Sciences, University of Turin, Ospedale S, Luigi, 10043 Orbassano, Torino, Italy
    BMC Genomics 9:291. 2008
  8. pmc The genome of the kinetoplastid parasite, Leishmania major
    Alasdair C Ivens
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK
    Science 309:436-42. 2005
  9. ncbi request reprint The Leishmania genome comes of Age
    A C Ivens
    The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
    Parasitol Today 15:225-31. 1999
  10. pmc The genome of the simian and human malaria parasite Plasmodium knowlesi
    A Pain
    Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK
    Nature 455:799-803. 2008

Collaborators

Detail Information

Publications12

  1. pmc Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum
    Gareth Bloomfield
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    Genome Biol 9:R75. 2008
    ..Duplications of stretches of the genome are an important source of individual genetic variation, but their unrecognized presence in laboratory organisms would be a confounding variable for genetic analysis...
  2. pmc Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa
    Carol J Loscher
    Smurfit Institute of Genetics, Trinity College Dublin, College Green, Dublin 2, Ireland
    Genome Biol 8:R248. 2007
    ..Little is known about the cellular mechanisms that connect mutations within RHO to eventual photoreceptor cell death by apoptosis...
  3. pmc Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common and specific effects from PAO1 and PA14 strains
    Sergio Carilla-Latorre
    Instituto de Investigaciones Biomedicas Alberto Sols, Universidad Autónoma de Madrid Consejo Superior de Investigaciones Científicas, Madrid, Spain
    BMC Microbiol 8:109. 2008
    ..aeruginosa and other pathogens, we used available genomic tools in this model system to study the transcriptional host response to P. aeruginosa infection...
  4. pmc Gene copy number variation throughout the Plasmodium falciparum genome
    Ian H Cheeseman
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    BMC Genomics 10:353. 2009
    ..Despite the known effects of CNV, little is known about its extent throughout the genome...
  5. pmc Detection of genome-wide polymorphisms in the AT-rich Plasmodium falciparum genome using a high-density microarray
    Hongying Jiang
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    BMC Genomics 9:398. 2008
    ..Here we evaluate polymorphism detection accuracy of a high-density 'tiling' microarray with 2.56 million probes by comparing single feature polymorphisms (SFP) calls from the microarray with known SNP among parasite isolates...
  6. pmc A software framework for microarray and gene expression object model (MAGE-OM) array design annotation
    Matloob Qureshi
    Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK
    BMC Genomics 9:133. 2008
    ..However, although the MAGE object model is flexible enough to support different annotation strategies, the annotation of array descriptions can be complex...
  7. pmc Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium
    Alessio Sillo
    Department of Clinical and Biological Sciences, University of Turin, Ospedale S, Luigi, 10043 Orbassano, Torino, Italy
    BMC Genomics 9:291. 2008
    ..We have investigated Dictyostelium differential gene expression during phagocytosis of non-pathogenic bacteria, using DNA microarrays, in order to identify molecular functions and novel genes involved in phagocytosis...
  8. pmc The genome of the kinetoplastid parasite, Leishmania major
    Alasdair C Ivens
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK
    Science 309:436-42. 2005
    ..Abundant RNA-binding proteins are encoded in the Tritryp genomes, consistent with active posttranscriptional regulation of gene expression...
  9. ncbi request reprint The Leishmania genome comes of Age
    A C Ivens
    The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
    Parasitol Today 15:225-31. 1999
    ....
  10. pmc The genome of the simian and human malaria parasite Plasmodium knowlesi
    A Pain
    Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK
    Nature 455:799-803. 2008
    ..One of these families, the KIRs, contains sequences that collectively match over one-half of the host CD99 extracellular domain, which may represent an unusual form of molecular mimicry...
  11. pmc (Beta alpha)8-barrel proteins of tryptophan biosynthesis in the hyperthermophile Thermotoga maritima
    R Sterner
    Abteilung fur Biophysikalische Chemie, Universitat Basel, Switzerland
    EMBO J 14:4395-402. 1995
    ..Another notable feature is the predicted lack of the N-terminal helix alpha 0 in the alpha-subunit of tryptophan synthase...
  12. ncbi request reprint Structure and sequence of the human homeobox gene HOX7
    J E Hewitt
    Department of Biochemistry and Molecular Genetics, St Mary s Hospital Medical School, Imperial College of Science, Technology, and Medicine, London, United Kingdom
    Genomics 11:670-8. 1991
    ..The region encompassing the promoter region, exon 1, and the 5' region of exon 2 have a higher than expected frequency of CpG dinucleotides; numerous sites for rare-cutter restriction enzymes are present, a characteristic of HTF islands...