Sean Humphray

Summary

Affiliation: Wellcome Trust Genome Campus
Country: UK

Publications

  1. pmc DNA sequence and analysis of human chromosome 9
    S J Humphray
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nature 429:369-74. 2004
  2. pmc Lessons learned from the initial sequencing of the pig genome: comparative analysis of an 8 Mb region of pig chromosome 17
    Elizabeth A Hart
    Wellcome Trust Sanger Institute, Wellcome Tust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Genome Biol 8:R168. 2007
  3. pmc A high utility integrated map of the pig genome
    Sean J Humphray
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA UK
    Genome Biol 8:R139. 2007
  4. pmc Definition of the zebrafish genome using flow cytometry and cytogenetic mapping
    Jennifer L Freeman
    Department of Pathology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    BMC Genomics 8:195. 2007
  5. pmc The zebrafish reference genome sequence and its relationship to the human genome
    Kerstin Howe
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nature 496:498-503. 2013
  6. pmc Genome-wide end-sequenced BAC resources for the NOD/MrkTac() and NOD/ShiLtJ() mouse genomes
    Charles A Steward
    The Wellcome Trust Sanger Institute, Hinxton, UK
    Genomics 95:105-10. 2010
  7. ncbi request reprint A genome-wide, end-sequenced 129Sv BAC library resource for targeting vector construction
    David J Adams
    The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK
    Genomics 86:753-8. 2005
  8. pmc A map of human genome variation from population-scale sequencing
    Richard M Durbin
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, UK
    Nature 467:1061-73. 2010
  9. ncbi request reprint Insight into the genome of Aspergillus fumigatus: analysis of a 922 kb region encompassing the nitrate assimilation gene cluster
    Arnab Pain
    The Pathogen Sequencing Unit, The Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Fungal Genet Biol 41:443-53. 2004
  10. pmc The variant call format and VCFtools
    Petr Danecek
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, UK
    Bioinformatics 27:2156-8. 2011

Collaborators

Detail Information

Publications11

  1. pmc DNA sequence and analysis of human chromosome 9
    S J Humphray
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nature 429:369-74. 2004
    ..We have also detected recently duplicated genes that exhibit different rates of sequence divergence, presumably reflecting natural selection...
  2. pmc Lessons learned from the initial sequencing of the pig genome: comparative analysis of an 8 Mb region of pig chromosome 17
    Elizabeth A Hart
    Wellcome Trust Sanger Institute, Wellcome Tust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Genome Biol 8:R168. 2007
    ..We report our findings comparing the annotation of draft sequence assembled at different depths of coverage...
  3. pmc A high utility integrated map of the pig genome
    Sean J Humphray
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA UK
    Genome Biol 8:R139. 2007
    ....
  4. pmc Definition of the zebrafish genome using flow cytometry and cytogenetic mapping
    Jennifer L Freeman
    Department of Pathology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    BMC Genomics 8:195. 2007
    ..Cytogenetic approaches provide "anchors" that can be integrated with accumulating genomic data...
  5. pmc The zebrafish reference genome sequence and its relationship to the human genome
    Kerstin Howe
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nature 496:498-503. 2013
    ....
  6. pmc Genome-wide end-sequenced BAC resources for the NOD/MrkTac() and NOD/ShiLtJ() mouse genomes
    Charles A Steward
    The Wellcome Trust Sanger Institute, Hinxton, UK
    Genomics 95:105-10. 2010
    ..These BAC libraries represent a powerful resource for functional studies, such as gene targeting in NOD embryonic stem (ES) cell lines, and for sequencing and mapping experiments...
  7. ncbi request reprint A genome-wide, end-sequenced 129Sv BAC library resource for targeting vector construction
    David J Adams
    The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK
    Genomics 86:753-8. 2005
    ..Furthermore, we show that targeting vectors containing DNA recombineered from this BAC library can be used to target genes efficiently in several 129-derived ES cell lines...
  8. pmc A map of human genome variation from population-scale sequencing
    Richard M Durbin
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, UK
    Nature 467:1061-73. 2010
    ..These methods and public data will support the next phase of human genetic research...
  9. ncbi request reprint Insight into the genome of Aspergillus fumigatus: analysis of a 922 kb region encompassing the nitrate assimilation gene cluster
    Arnab Pain
    The Pathogen Sequencing Unit, The Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Fungal Genet Biol 41:443-53. 2004
    ..We observed large scale synteny between A. fumigatus and Aspergillus nidulans by comparing this sequence to the A. nidulans genetic map of linkage group VIII...
  10. pmc The variant call format and VCFtools
    Petr Danecek
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, UK
    Bioinformatics 27:2156-8. 2011
    ..VCFtools is a software suite that implements various utilities for processing VCF files, including validation, merging, comparing and also provides a general Perl API...
  11. pmc Variation in genome-wide mutation rates within and between human families
    Donald F Conrad
    Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
    Nat Genet 43:712-4. 2011
    ..These observations suggest considerable variation in mutation rates within and between families...