Christiane Hertz Fowler

Summary

Affiliation: Wellcome Trust Genome Campus
Country: UK

Publications

  1. ncbi request reprint Integration of tools and resources for display and analysis of genomic data for protozoan parasites
    Martin Aslett
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Int J Parasitol 35:481-93. 2005
  2. pmc The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis
    Andrew P Jackson
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
    PLoS Negl Trop Dis 4:e658. 2010
  3. pmc GeneDB: a resource for prokaryotic and eukaryotic organisms
    Christiane Hertz-Fowler
    The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nucleic Acids Res 32:D339-43. 2004
  4. pmc Telomeric expression sites are highly conserved in Trypanosoma brucei
    Christiane Hertz-Fowler
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
    PLoS ONE 3:e3527. 2008
  5. doi request reprint Sequence data swell for nematodes
    Christiane Hertz-Fowler
    Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
    Nat Rev Microbiol 6:800-1. 2008
  6. pmc The genome of the kinetoplastid parasite, Leishmania major
    Alasdair C Ivens
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK
    Science 309:436-42. 2005
  7. ncbi request reprint The genome of the African trypanosome Trypanosoma brucei
    Matthew Berriman
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
    Science 309:416-22. 2005
  8. ncbi request reprint Comparative genomics of trypanosomatid parasitic protozoa
    Najib M El-Sayed
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 309:404-9. 2005
  9. ncbi request reprint A feast of protozoan genomes
    Christiane Hertz-Fowler
    Nat Rev Microbiol 3:670-1. 2005
  10. ncbi request reprint Continuing tsetse and Trypanosoma genome sequencing projects
    Christiane Hertz-Fowler
    Trends Parasitol 20:308-9; author reply 309-10. 2004

Detail Information

Publications15

  1. ncbi request reprint Integration of tools and resources for display and analysis of genomic data for protozoan parasites
    Martin Aslett
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Int J Parasitol 35:481-93. 2005
    ..We then focus on the GeneDB project, detailing the features and tools currently available through it. Finally, we discuss data curation and its importance in keeping genomic data 'relevant' to the research community...
  2. pmc The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis
    Andrew P Jackson
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom
    PLoS Negl Trop Dis 4:e658. 2010
    ..b. gambiense and the reference genome. We sought to identify features that were uniquely associated with T. b. gambiense and its ability to infect humans...
  3. pmc GeneDB: a resource for prokaryotic and eukaryotic organisms
    Christiane Hertz-Fowler
    The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nucleic Acids Res 32:D339-43. 2004
    ..The current release stores 11 datasets of which six are curated and maintained by biologists, who review and incorporate information from the scientific literature, public databases and the respective research communities...
  4. pmc Telomeric expression sites are highly conserved in Trypanosoma brucei
    Christiane Hertz-Fowler
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
    PLoS ONE 3:e3527. 2008
    ..This work opens important perspectives in understanding the molecular mechanisms of antigenic variation, a widely used strategy for immune evasion in pathogens, and telomere biology...
  5. doi request reprint Sequence data swell for nematodes
    Christiane Hertz-Fowler
    Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
    Nat Rev Microbiol 6:800-1. 2008
    ..This month's Genome Watch describes genomes of several nematodes, including that of the human filarial parasite Brugia malayi...
  6. pmc The genome of the kinetoplastid parasite, Leishmania major
    Alasdair C Ivens
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK
    Science 309:436-42. 2005
    ..Abundant RNA-binding proteins are encoded in the Tritryp genomes, consistent with active posttranscriptional regulation of gene expression...
  7. ncbi request reprint The genome of the African trypanosome Trypanosoma brucei
    Matthew Berriman
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
    Science 309:416-22. 2005
    ..brucei and the greatest in L. major. Horizontal transfer of genes of bacterial origin has contributed to some of the metabolic differences in these parasites, and a number of novel potential drug targets have been identified...
  8. ncbi request reprint Comparative genomics of trypanosomatid parasitic protozoa
    Najib M El-Sayed
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 309:404-9. 2005
    ..Contrary to recent reports, our analyses reveal no evidence that these species are descended from an ancestor that contained a photosynthetic endosymbiont...
  9. ncbi request reprint A feast of protozoan genomes
    Christiane Hertz-Fowler
    Nat Rev Microbiol 3:670-1. 2005
  10. ncbi request reprint Continuing tsetse and Trypanosoma genome sequencing projects
    Christiane Hertz-Fowler
    Trends Parasitol 20:308-9; author reply 309-10. 2004
  11. ncbi request reprint Parasite genome databases and web-based resources
    Christiane Hertz-Fowler
    Pathogen Sequencing Unit, Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK
    Methods Mol Biol 270:45-74. 2004
    ..Particular attention is given to three databases, GeneDB (http://www.genedb.org/), PlasmoDB (http://plasmodb. org/), and tigr db, detailing the scope of each database and the tools available for data querying and retrieval...
  12. pmc The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism
    Neil Hall
    The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
    Nucleic Acids Res 31:4864-73. 2003
    ..Genetic polymorphisms are exceptionally rare in sequences located within and around the strand-switches between several gene clusters...
  13. pmc The minimum information about a genome sequence (MIGS) specification
    Dawn Field
    Natural Environmental Research Council Centre for Ecology and Hydrology, Oxford OX1 3SR, UK
    Nat Biotechnol 26:541-7. 2008
    ..As part of its wider goals, the GSC also supports improving the 'transparency' of the information contained in existing genomic databases...
  14. doi request reprint Genomic adaptation: a fungal perspective
    Arnab Pain
    Nat Rev Microbiol 6:572-3. 2008
  15. pmc Genomic-scale prioritization of drug targets: the TDR Targets database
    Fernan Aguero
    Instituto de Investigaciones Biotecnologicas, Universidad Nacional de General San Martin, San Martin 1650, Buenos Aires, Argentina
    Nat Rev Drug Discov 7:900-7. 2008
    ..By allowing the integration and weighting of this information, this database aims to facilitate the identification and prioritization of candidate drug targets for pathogens...