Affiliation: Wellcome Trust Genome Campus
Kent R, Modrzynska K, Cameron R, Philip N, Billker O, Waters A. Inducible developmental reprogramming redefines commitment to sexual development in the malaria parasite Plasmodium berghei. Nat Microbiol. 2018;3:1206-1213 pubmed publisher
..These data provide entry points for further detailed characterization of the key process required for malaria transmission. ..
Schwach F, Bushell E, Gomes A, Anar B, Girling G, Herd C, et al
. PlasmoGEM, a database supporting a community resource for large-scale experimental genetics in malaria parasites. Nucleic Acids Res. 2015;43:D1176-82 pubmed publisher
..We also make gDNA library clones and intermediate vectors available for researchers to produce vectors for themselves. ..
Modrzynska K, Pfander C, Chappell L, Yu L, Suarez C, Dundas K, et al
. A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle. Cell Host Microbe. 2017;21:11-22 pubmed publisher
..We propose that stage-specific interactions between ApiAP2 proteins on partly overlapping sets of target genes generate the complex transcriptional network that controls the Plasmodium life cycle. ..
Invergo B, Brochet M, Yu L, Choudhary J, Beltrao P, Billker O. Sub-minute Phosphoregulation of Cell Cycle Systems during Plasmodium Gamete Formation. Cell Rep. 2017;21:2017-2029 pubmed publisher
..The results reveal the central role of protein phosphorylation in the atypical cell cycle regulation of a divergent eukaryote. ..