Research Topics
| Alain VuylstekeSummaryCountry: UK Publications
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Publications
The Papworth Bleeding Risk Score: a stratification scheme for identifying cardiac surgery patients at risk of excessive early postoperative bleedingAlain Vuylsteke
Papworth Hospital, Cambridge, CB23 3RE, UK
Eur J Cardiothorac Surg 39:924-30. 2011..We have developed a risk stratification score to identify cardiac surgical patients at higher risk of severe postoperative bleeding to aid a decision of whether to use a specific intervention preoperatively...
Characteristics, practice patterns, and outcomes in patients with acute hypertension: European registry for Studying the Treatment of Acute hyperTension (Euro-STAT)Alain Vuylsteke
Department of Anaesthesia and Intensive Care, Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridge, CB23 3RE, UK
Crit Care 15:R271. 2011....
Circulatory arrest versus cerebral perfusion during pulmonary endarterectomy surgery (PEACOG): a randomised controlled trialAlain Vuylsteke
Papworth Hospital NHS Foundation Trust, Cambridge, UK
Lancet 378:1379-87. 2011..We aimed to assess the benefits of the maintenance of antegrade cerebral perfusion (ACP) compared with deep hypothermic circulatory arrest (DHCA)...
Safety and efficacy of aprotinin and tranexamic acid in pulmonary endarterectomy surgery with hypothermia: review of 200 patientsMarius Berman
Department of Cardiothoracic Surgery, Papworth Hospital, Cambridge, United Kingdom
Ann Thorac Surg 90:1432-6. 2010..The effectiveness and safety of aprotinin in cardiac surgery has been questioned. The study aim was to compare both the blood-sparing effect and side effects of aprotinin and tranexamic acid in patients undergoing pulmonary endarterectomy...
A lipopolysaccharide adsorber in adult cardiopulmonary bypass: a single centre randomised controlled pilot trialRavi J De Silva
Department of Anaesthesia and Intensive Care, Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridge CB23 3RE, UK
Interact Cardiovasc Thorac Surg 11:86-92. 2010..The aim of this study was to describe the biochemical effects and safety of selective removal of endotoxin from whole blood using a lipopolysaccharide adsorber during complex cardiac surgery...
Successful extracorporeal membrane oxygenation support after pulmonary thromboendarterectomyMarius Berman
Department of Cardiothoracic Surgery, Papworth Hospital, Papworth Everard, Cambridge, United Kingdom
Ann Thorac Surg 86:1261-7. 2008..Since 2005 we have used venoarterial extracorporeal membrane oxygenation (ECMO) support in this group that has no other therapeutic option. We review our experience of early ECMO support in the severely compromised patient's post-PTE...
A randomized controlled trial of cell salvage in routine cardiac surgeryAndrew A Klein
Department of Anaesthesia, Papworth Hospital, Cambridge, CB23 3RE, UK
Anesth Analg 107:1487-95. 2008....
Lithium-induced nephrogenic diabetes insipidus after coronary artery bypassMatthew F Leeman
Department of Cardiothoracic Surgery, Papworth Hospital NHS Trust, Cambridgeshire, United Kingdom
Ann Thorac Surg 84:656-7. 2007..In patients on long-term lithium therapy, the potentially life-threatening complication of lithium-induced nephrogenic diabetes insipidus should be specifically anticipated and managed...
Allogenic blood transfusion does not predispose to infection after cardiac surgeryZiad A Ali
Department of Cardiothoracic Surgery, Papworth Hospital, Papworth Everard, Cambridge, United Kingdom
Ann Thorac Surg 78:1542-6. 2004..77). CONCLUSIONS: The administration of blood per se did not lead to increased postoperative infection. Clinicians should reconsider withholding blood transfusion in patients solely owing to concerns of predisposition to infection...
Do you know a pneumo?Andrew J Drain
Papworth Hospital, Papworth Everard, Cambridge CB3 8RE, UK
J Cardiothorac Vasc Anesth 20:748-50. 2006
Biological efficacy of low against medium dose aspirin regimen after coronary surgery: analysis of platelet functionJacqueline Cornelissen
Department of Clinical Pharmacology, Papworth Hospital NHS Trust, Cambridge, CB3 8RE, UK
Thromb Haemost 95:476-82. 2006..In summary, there was no evidence for inherent or acquired aspirin-resistance in this surgical population, or for the involvement of either COX-2 or p38-MAPK...
APT070 inhibits complement activation during in vitro cardiopulmonary bypassRavi J De Silva
Papworth Hospital NHS Trust, Papworth Everard, Cambridgeshire CB3 8RE, UK
Eur J Cardiothorac Surg 30:72-6. 2006..They have been shown to be activated during cardiopulmonary bypass (CPB), and may be responsible for the inflammatory response to CPB. We looked at the effect of APT070, an anti-complement agent, on human blood during in vitro CPB...
Perioperative melatonin secretion in patients undergoing coronary artery bypass graftingXiangyang Guo
Anaesthetic Research Unit, Papworth Hospital, Cambridge, UK
Anesth Analg 94:1085-91, table of contents. 2002..Melatonin secretion was disturbed during and immediately after surgery but had recovered a circadian rhythm 24 h later, raising the question of whether melatonin should be supplemented before cardiac surgery...
