Margus Varjak

Summary

Country: UK

Publications

  1. Donald C, Varjak M, Aguiar E, Marques J, Sreenu V, Schnettler E, et al. Antiviral RNA Interference Activity in Cells of the Predatory Mosquito, Toxorhynchites amboinensis. Viruses. 2018;10: pubmed publisher
    ..Understanding their ability to manage arboviral infections will be advantageous when assessing these and similar species as biological control agents. ..
  2. Mutso M, Morro A, Smedberg C, Kasvandik S, Aquilimeba M, Teppor M, et al. Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus. Viruses. 2018;10: pubmed publisher
    ..Similar to CD2AP, its homolog SH3KBP1 also bound the identified motif in CHIKV and SFV nsP3. ..
  3. Varjak M, Dietrich I, Sreenu V, Till B, Merits A, Kohl A, et al. Spindle-E Acts Antivirally Against Alphaviruses in Mosquito Cells. Viruses. 2018;10: pubmed publisher
    ..Surprisingly, this effect was found to be independent of the siRNA and piRNA pathways in Ae. aegypti cells and specific for alphaviruses. This suggests a small RNA-independent antiviral function for this protein in mosquitoes. ..
  4. Royle J, Donald C, Merits A, Kohl A, Varjak M. Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses. Vet J. 2017;230:62-64 pubmed publisher