Bernhard Zimmermann

Summary

Affiliation: University of the West of England
Country: UK

Publications

  1. ncbi Optimized real-time quantitative PCR measurement of male fetal DNA in maternal plasma
    Bernhard Zimmermann
    University Women s Hospital Department of Research, University Hospital Basel, Basel, Switzerland
    Clin Chem 51:1598-604. 2005
  2. ncbi Real-time quantitative polymerase chain reaction measurement of male fetal DNA in maternal plasma
    Bernhard Zimmermann
    University Women s Hospital Department of Research, University Hospital Basel, Switzerland
    Methods Mol Med 132:43-9. 2007
  3. ncbi Detection of paternally inherited fetal point mutations for beta-thalassemia using size-fractionated cell-free DNA in maternal plasma
    Ying Li
    Laboratory for Prenatal Medicine, University Women's Hospital/Department of Research, Basel, Switzerland
    JAMA 293:843-9. 2005
  4. ncbi Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms
    Ying Li
    University Women's Hospital/Department of Research, University of Basel, Basel, Switzerland
    Clin Chem 50:1002-11. 2004
  5. ncbi Treatment of maternal blood samples with formaldehyde does not alter the proportion of circulatory fetal nucleic acids (DNA and mRNA) in maternal plasma
    Satheesh Kumar Reddy Chinnapapagari
    Department of Research, University Women's Hospital, Basel, Switzerland
    Clin Chem 51:652-5. 2005
  6. ncbi Nucleic acid based biosensors: the desires of the user
    Sinuhe Hahn
    Laboratory for Prenatal Medicine, University Women s Hospital Department of Research, University of Basel, Spitalstrasse 21, CH 4031 Basel, Switzerland
    Bioelectrochemistry 67:151-4. 2005
  7. ncbi Novel real-time quantitative PCR test for trisomy 21
    Bernhard Zimmermann
    Laboratory for Prenatal Medicine, Department of Obstetrics and Gynaecology, University of Basel, CH 4031 Basel, Switzerland
    Clin Chem 48:362-3. 2002
  8. ncbi Staphylococcus aureus infection caused by a Panton Valentine leukocidin-producing strain
    Christian Aepinus
    Pediatr Infect Dis J 24:284-5. 2005
  9. ncbi Inability to clonally expand fetal progenitors from maternal blood
    Bernhard Zimmermann
    Department of Obstetrics and Gynaecology, University of Basel, Switzerland
    Fetal Diagn Ther 17:97-100. 2002
  10. ncbi Use of real-time polymerase chain reaction for the detection of fetal aneuploidies
    Bernhard Zimmermann
    Centre for Research in Biomedicine, University of the West of England, Bristol, UK
    Methods Mol Biol 336:83-100. 2006

Collaborators

Detail Information

Publications12

  1. ncbi Optimized real-time quantitative PCR measurement of male fetal DNA in maternal plasma
    Bernhard Zimmermann
    University Women s Hospital Department of Research, University Hospital Basel, Basel, Switzerland
    Clin Chem 51:1598-604. 2005
    ..The circulating concentrations of single-copy fetal genes, however, are close to the detection limits of PCR methods...
  2. ncbi Real-time quantitative polymerase chain reaction measurement of male fetal DNA in maternal plasma
    Bernhard Zimmermann
    University Women s Hospital Department of Research, University Hospital Basel, Switzerland
    Methods Mol Med 132:43-9. 2007
    ..This chapter presents the basic methodology used in this noninvasive analysis...
  3. ncbi Detection of paternally inherited fetal point mutations for beta-thalassemia using size-fractionated cell-free DNA in maternal plasma
    Ying Li
    Laboratory for Prenatal Medicine, University Women's Hospital/Department of Research, Basel, Switzerland
    JAMA 293:843-9. 2005
    ..8%, with classified cases removed. CONCLUSION: Our recently described technique of the size-fractionation of circulatory DNA in maternal plasma may be potentially useful for the noninvasive prenatal determination of fetal point mutations...
  4. ncbi Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms
    Ying Li
    University Women's Hospital/Department of Research, University of Basel, Basel, Switzerland
    Clin Chem 50:1002-11. 2004
    ..CONCLUSIONS: Circulatory fetal DNA can be enriched by size selection of fragment sizes less than approximately 0.3 kb. Such selection permits easier analysis of both paternally and maternally inherited DNA polymorphisms...
  5. ncbi Treatment of maternal blood samples with formaldehyde does not alter the proportion of circulatory fetal nucleic acids (DNA and mRNA) in maternal plasma
    Satheesh Kumar Reddy Chinnapapagari
    Department of Research, University Women's Hospital, Basel, Switzerland
    Clin Chem 51:652-5. 2005
  6. ncbi Nucleic acid based biosensors: the desires of the user
    Sinuhe Hahn
    Laboratory for Prenatal Medicine, University Women s Hospital Department of Research, University of Basel, Spitalstrasse 21, CH 4031 Basel, Switzerland
    Bioelectrochemistry 67:151-4. 2005
    ..In this review, we provide an overview of the current state of the art concerning the high-throughput analysis of nucleic acids, and address future requirements, which will hopefully be met by new biosensor-based developments...
  7. ncbi Novel real-time quantitative PCR test for trisomy 21
    Bernhard Zimmermann
    Laboratory for Prenatal Medicine, Department of Obstetrics and Gynaecology, University of Basel, CH 4031 Basel, Switzerland
    Clin Chem 48:362-3. 2002
  8. ncbi Staphylococcus aureus infection caused by a Panton Valentine leukocidin-producing strain
    Christian Aepinus
    Pediatr Infect Dis J 24:284-5. 2005
  9. ncbi Inability to clonally expand fetal progenitors from maternal blood
    Bernhard Zimmermann
    Department of Obstetrics and Gynaecology, University of Basel, Switzerland
    Fetal Diagn Ther 17:97-100. 2002
    ..No colonies were detected of fetal origin. CONCLUSIONS: The clonal expansion of single fetal colonies from the maternal circulation is not feasible by current methods...
  10. ncbi Use of real-time polymerase chain reaction for the detection of fetal aneuploidies
    Bernhard Zimmermann
    Centre for Research in Biomedicine, University of the West of England, Bristol, UK
    Methods Mol Biol 336:83-100. 2006
    ..5-fold differences in gene copy number...
  11. ncbi Reliable detection of trisomy 21 using MALDI-TOF mass spectrometry
    Dorothy J Huang
    Laboratory for Prenatal Medicine University Women's Hospital, Department of Research Spitalstrasse 21, CH4031 Basel, Switzerland
    Genet Med 8:728-34. 2006
    ..Its amenability to high-throughput analysis and high degree of multiplexing make it a potential future diagnostic tool for the detection of other aneuploidies as well...
  12. ncbi Molecular methods for rapid detection of aneuploidy
    Lech Dudarewicz
    Department of Medical Genetics, Polish Mother s Memorial Hospital Research Institute, Rzgowska 281 289, 93 338 Łódź, Poland
    J Appl Genet 46:207-15. 2005
    ....