Yong Ming Zhu
Affiliation: University of Sheffield
- Interleukin-8/CXCL8 is a growth factor for human lung cancer cellsY M Zhu
Department of Clinical Oncology, Institute for Cancer Studies, University of Sheffield Medical School, Beech Hill Road, Sheffield S10 2RX, UK
Br J Cancer 91:1970-6. 2004..In conclusion, IL-8 can act as an autocrine and/or paracrine growth factor for lung cancer cells, and the mitogenic function of IL-8 in lung cancer is mediated mainly by CXCR1 receptor...
- Mitogenic effects of interleukin-8/CXCL8 on cancer cellsYong Ming Zhu
University of Sheffield Medical School, Institute for Cancer Studies, Department of Clinical Oncology, Division of Genomic Medicine, Sheffield, UK
Future Oncol 1:699-704. 2005..The mitogenic effects of IL-8 directly stimulate growth of cancer mass, and it may play a critical role for cancer cells to regrow in metastatic sites...
- Production and upregulation of granulocyte chemotactic protein-2/CXCL6 by IL-1beta and hypoxia in small cell lung cancerY M Zhu
Department of Clinical Oncology, Division of Genomic Medicine, School of Medicine and Biomedical Sciences, Institute for Cancer Studies, University of Sheffield, UK
Br J Cancer 94:1936-41. 2006..Taken together, these results suggest an important role for GCP-2 as an autocrine mitogen in the growth and metastasis of SCLC...
- Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cellsYong Ming Zhu
Institute for Cancer Studies, School of Medicine and Biomedical Science, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, UK
BMC Cancer 8:218. 2008..We speculated that inhibition of COX-2 activity might reduce expression of the pro-angiogenic factors vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) in lung cancer cells...