Jing Hua Zhao

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi GENECOUNTING: haplotype analysis with missing genotypes
    Jing Hua Zhao
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Bioinformatics 18:1694-5. 2002
  2. ncbi 2LD, GENECOUNTING and HAP: Computer programs for linkage disequilibrium analysis
    Jing Hua Zhao
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Bioinformatics 20:1325-6. 2004
  3. ncbi Mixed-effects Cox models of alcohol dependence in extended families
    Jing Hua Zhao
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    BMC Genet 6:S127. 2005
  4. ncbi Faster haplotype frequency estimation using unrelated subjects
    Jing Hua Zhao
    Department of Psychological Medicine, Developmental Psychiatry Research Centre, Institute of Psychiatry, Denmark Hill, London, UK
    Hum Hered 53:36-41. 2002
  5. ncbi Generic number systems and haplotype analysis
    Jing Hua Zhao
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, SE5 8AF, London, UK
    Comput Methods Programs Biomed 70:1-9. 2003
  6. ncbi Linkage disequilibrium analysis of polymorphisms in the gene for myelin oligodendrocyte glycoprotein in Tourette's syndrome patients from a Chinese sample
    Yi Huang
    Department of Psychological Medicine and Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 124:76-80. 2004
  7. ncbi Estimating haplotype relative risks on human survival in population-based association studies
    Qihua Tan
    Department of Clinical Biochemistry and Genetics, KKA, Odense University Hospital, DK 5000 Odense, Denmark
    Hum Hered 59:88-97. 2005
  8. ncbi Haplotype association analysis of human disease traits using genotype data of unrelated individuals
    Qihua Tan
    Department of Clinical Biochemistry and Genetics KKA, Odense University Hospital, Denmark
    Genet Res 86:223-31. 2005
  9. ncbi Integrated analysis of genetic data with R
    Jing Hua Zhao
    Strangeways Research Laboratory, Wort s Causeway, Cambridge, CB1 8RN, UK
    Hum Genomics 2:258-65. 2006
  10. ncbi Retrospective analysis of main and interaction effects in genetic association studies of human complex traits
    Qihua Tan
    Epidemiology, Institute of Public Health, University of Southern Denmark, Denmark
    BMC Genet 8:70. 2007

Collaborators

Detail Information

Publications13

  1. ncbi GENECOUNTING: haplotype analysis with missing genotypes
    Jing Hua Zhao
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Bioinformatics 18:1694-5. 2002
    ..A general algorithm is described for haplotype analysis of unrelated individuals with missing genotypes. It can handle problems involving multiple polymorphic markers with missing data...
  2. ncbi 2LD, GENECOUNTING and HAP: Computer programs for linkage disequilibrium analysis
    Jing Hua Zhao
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Bioinformatics 20:1325-6. 2004
    ..AVAILABILITY: Programs 2LD, GENECOUNTING and HAP are available on Internet from http://www.hgmp.mrc.ac.uk/~jzhao and http://www.iop.kcl.ac.uk/IoP/Departments/PsychMed/GEpiBSt/software.shtml..
  3. ncbi Mixed-effects Cox models of alcohol dependence in extended families
    Jing Hua Zhao
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    BMC Genet 6:S127. 2005
    ..D4S1645 had the largest variance and contribution to the log-likelihood on chromosome 4, but the significance of this finding requires further investigation...
  4. ncbi Faster haplotype frequency estimation using unrelated subjects
    Jing Hua Zhao
    Department of Psychological Medicine, Developmental Psychiatry Research Centre, Institute of Psychiatry, Denmark Hill, London, UK
    Hum Hered 53:36-41. 2002
    ..Our implementation also allows the rapid calculation of permutation-based LD measures and related statistics...
  5. ncbi Generic number systems and haplotype analysis
    Jing Hua Zhao
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, SE5 8AF, London, UK
    Comput Methods Programs Biomed 70:1-9. 2003
    ..Implementation of gene-counting using these algorithms avoids use of multilocus genotype identifier and improves its portability to other analysis...
  6. ncbi Linkage disequilibrium analysis of polymorphisms in the gene for myelin oligodendrocyte glycoprotein in Tourette's syndrome patients from a Chinese sample
    Yi Huang
    Department of Psychological Medicine and Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 124:76-80. 2004
    ..000, P = 0.046) which did not survive correction for multiple testing. Our results suggest that there is no association between the MOG gene polymorphisms we tested and GTS...
  7. ncbi Estimating haplotype relative risks on human survival in population-based association studies
    Qihua Tan
    Department of Clinical Biochemistry and Genetics, KKA, Odense University Hospital, DK 5000 Odense, Denmark
    Hum Hered 59:88-97. 2005
    ..Results from both simulation and model application indicate that our survival analysis model is an efficient method for inferring haplotype effects on human survival in population-based association studies...
  8. ncbi Haplotype association analysis of human disease traits using genotype data of unrelated individuals
    Qihua Tan
    Department of Clinical Biochemistry and Genetics KKA, Odense University Hospital, Denmark
    Genet Res 86:223-31. 2005
    ..We show, by applying the model to an empirical data set, that our method based on the well-known logistic regression model is a useful tool for haplotype association analysis of human disease traits...
  9. ncbi Integrated analysis of genetic data with R
    Jing Hua Zhao
    Strangeways Research Laboratory, Wort s Causeway, Cambridge, CB1 8RN, UK
    Hum Genomics 2:258-65. 2006
    ....
  10. ncbi Retrospective analysis of main and interaction effects in genetic association studies of human complex traits
    Qihua Tan
    Epidemiology, Institute of Public Health, University of Southern Denmark, Denmark
    BMC Genet 8:70. 2007
    ..Performance of our method in detecting interaction effect is compared with that of the case-only model...
  11. ncbi Data mining of RNA expression and DNA genotype data: presentation group 5 contributions to Genetic Analysis Workshop 15
    Catherine T Falk
    Genet Epidemiol 31:S43-50. 2007
    ..The collection of papers and methods offer a starting point for further exploration of complex interactions in human genetic data now readily available...
  12. ncbi Genome-wide association analysis identifies 20 loci that influence adult height
    Michael N Weedon
    Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, Magdalen Road, Exeter EX1 2LU, UK
    Nat Genet 40:575-83. 2008
    ..Finally, our results provide insights into the genetic architecture of a classic quantitative trait...
  13. ncbi Common variants near MC4R are associated with fat mass, weight and risk of obesity
    Ruth J F Loos
    MRC Epidemiology Unit, Addenbrooke s Hospital, Cambridge CB2 0QQ, UK
    Nat Genet 40:768-75. 2008
    ....