Lina Zgaga

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Model selection approach suggests causal association between 25-hydroxyvitamin D and colorectal cancer
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 8:e63475. 2013
  2. pmc The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e38123. 2012
  3. pmc An evaluation of the emerging vaccines and immunotherapy against staphylococcal pneumonia in children
    Tanvir Huda
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    BMC Public Health 11:S27. 2011
  4. pmc Diet, environmental factors, and lifestyle underlie the high prevalence of vitamin D deficiency in healthy adults in Scotland, and supplementation reduces the proportion that are severely deficient
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh EH8 9AG, UK
    J Nutr 141:1535-42. 2011
  5. pmc Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e37662. 2012
  6. pmc An evaluation of respiratory administration of measles vaccine for prevention of acute lower respiratory infections in children
    Daisy Higginson
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S31. 2011
  7. doi request reprint Individual multi-locus heterozygosity is associated with lower morning plasma cortisol concentrations
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK
    Eur J Endocrinol 169:59-64. 2013
  8. pmc Abundant pleiotropy in human complex diseases and traits
    Shanya Sivakumaran
    Centre for Population Health Sciences, The University of Edinburgh, Edinburgh EH8 9AG, UK
    Am J Hum Genet 89:607-18. 2011
  9. pmc An evaluation of emerging vaccines for childhood meningococcal disease
    Debajeet Choudhuri
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S29. 2011
  10. doi request reprint Systematic meta-analyses and field synopsis of genetic association studies in colorectal cancer
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, UK
    J Natl Cancer Inst 104:1433-57. 2012

Detail Information

Publications19

  1. pmc Model selection approach suggests causal association between 25-hydroxyvitamin D and colorectal cancer
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 8:e63475. 2013
    ..We investigate the direction of causation between vitamin D and CRC by extending the conventional approaches to allow pleiotropic relationships and by explicitly modelling unmeasured confounders...
  2. pmc The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e38123. 2012
    ..Objective of this study was to investigate the association between plasma urate concentration and: a) food items: dairy, sugar-sweetened beverages (SSB) and purine-rich vegetables; b) related nutrients: lactose, calcium and fructose...
  3. pmc An evaluation of the emerging vaccines and immunotherapy against staphylococcal pneumonia in children
    Tanvir Huda
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    BMC Public Health 11:S27. 2011
    ..Currently there are at least seven vaccine and immunotherapy candidates against S. aureus in the developmental phase targeting both active and passive immunization...
  4. pmc Diet, environmental factors, and lifestyle underlie the high prevalence of vitamin D deficiency in healthy adults in Scotland, and supplementation reduces the proportion that are severely deficient
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh EH8 9AG, UK
    J Nutr 141:1535-42. 2011
    ....
  5. pmc Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e37662. 2012
    ..To elucidate the effect of vitamin D on CRC cancer risk, additional large studies of vitamin D and CRC risk are required and/or the application of alternative methods that are less sensitive to weak instrument restrictions...
  6. pmc An evaluation of respiratory administration of measles vaccine for prevention of acute lower respiratory infections in children
    Daisy Higginson
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S31. 2011
    ..Aerosolised measles vaccines are now under development with the hope of challenging the delivery factors currently limiting the coverage of the existing vaccine...
  7. doi request reprint Individual multi-locus heterozygosity is associated with lower morning plasma cortisol concentrations
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK
    Eur J Endocrinol 169:59-64. 2013
    ..We hypothesized that heterozygosity ameliorates the biological response to a given level of perceived stress, reflected in lower plasma cortisol concentrations...
  8. pmc Abundant pleiotropy in human complex diseases and traits
    Shanya Sivakumaran
    Centre for Population Health Sciences, The University of Edinburgh, Edinburgh EH8 9AG, UK
    Am J Hum Genet 89:607-18. 2011
    ....
  9. pmc An evaluation of emerging vaccines for childhood meningococcal disease
    Debajeet Choudhuri
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S29. 2011
    ..We aimed to perform a structured assessment of these emerging meningococcal vaccines as a means of reducing global meningococcal disease burden among children under 5 years of age...
  10. doi request reprint Systematic meta-analyses and field synopsis of genetic association studies in colorectal cancer
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, UK
    J Natl Cancer Inst 104:1433-57. 2012
    ..chs.med.ed.ac.uk/CRCgene/)...
  11. pmc An evaluation of oxygen systems for treatment of childhood pneumonia
    Alastair G Catto
    Centre for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, UK
    BMC Public Health 11:S28. 2011
    ..This review aims to assess the utility of oxygen systems as a method for reducing childhood mortality from pneumonia...
  12. pmc An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S30. 2011
    ..Currently there are several vaccine and immunoprophylaxis candidates against RSV in the developmental phase targeting active and passive immunization...
  13. doi request reprint The TCF7L2 diabetes risk variant is associated with HbA₁(C) levels: a genome-wide association meta-analysis
    Christopher S Franklin
    Centre for Population Health Sciences, University of Edinburgh, Scotland
    Ann Hum Genet 74:471-8. 2010
    ..The strongest association was with the TCF7L2 gene (rs7903146, P= 1.48 × 10⁻⁷). This is also the strongest common genetic risk factor for T2D but it has not been identified in previous genome-wide studies of glycated haemoglobin...
  14. pmc Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh EH8 9AG, UK
    BMJ 348:g2035. 2014
    ..To evaluate the breadth, validity, and presence of biases of the associations of vitamin D with diverse outcomes...
  15. pmc Genome-wide association uncovers shared genetic effects among personality traits and mood states
    Michelle Luciano
    Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK
    Am J Med Genet B Neuropsychiatr Genet 159:684-95. 2012
    ..The variance explained by individual SNPs was very small (up to 1%) confirming that there are no moderate/large effects of common SNPs on personality and related traits...
  16. ncbi request reprint Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk
    Malcolm G Dunlop
    Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council MRC Human Genetics Unit, Edinburgh, UK
    Nat Genet 44:770-6. 2012
    ..2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC...
  17. doi request reprint New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8
    Veronique Vitart
    MRC Human Genetics Unit, IGMM, Edinburgh, UK
    Hum Mol Genet 19:4304-11. 2010
    ..These associations offer mechanistic insights into the regulation of CCT and offer new candidate genes for susceptibility to common disorders in which CCT has been implicated, including primary open-angle glaucoma and keratoconus...
  18. pmc Genetic comparison of a Croatian isolate and CEPH European founders
    Pau Navarro
    Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK
    Genet Epidemiol 34:140-5. 2010
    ....
  19. pmc An evaluation of emerging vaccines for childhood pneumococcal pneumonia
    Julia Webster
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S26. 2011
    ....