Research Topics
Genomes and GenesSpecies | Maurice P A ZeegersSummaryAffiliation: University of Birmingham Country: UK Publications
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Publications
Genes in the polyamine biosynthesis pathway may be involved in prostate cancer susceptibilityMaurice P Zeegers
University of Birmingham, Department of Public Health and Epidemiology, Public Health Building, Edgbaston, Birmingham, UK
Future Oncol 1:683-8. 2005..Polyamines are also involved in prostate diagnosis and treatment. Therefore, the authors suggest that future oncologic research to identify candidate regions for prostate cancer should focus on genes dysregulated in this pathway...
Designing the selenium and bladder cancer trial (SELEBLAT), a phase lll randomized chemoprevention study with selenium on recurrence of bladder cancer in BelgiumMaria E Goossens
Department of General Practice, University of Leuven, ACHG KU Leuven, Kapucijnenvoer 33, Blok J, Bus 7001, 3000 Leuven, Belgium
BMC Urol 12:8. 2012..8%). Previous epidemiological studies have consistently reported that selenium concentrations were inversely associated with the risk of bladder cancer. This suggests that selenium may also be suitable for chemoprevention of recurrence...
The use of the SF-36 questionnaire in adult survivors of childhood cancer: evaluation of data quality, score reliability, and scaling assumptionsRaoul C Reulen
Centre for Childhood Cancer Survivor Studies, University of Birmingham, Department of Public Health and Epidemiology, Edgbaston, Birmingham, B15 2TT, UK
Health Qual Life Outcomes 4:77. 2006..The aim of this paper was to determine whether the SF-36 questionnaire is a valid and reliable instrument in assessing self-perceived health status of adult survivors of childhood cancer...
The West Midlands Bladder Cancer Prognosis Programme: rationale and designMaurice P Zeegers
Department of Public Health, Epidemiology and Biostatistics, University of Birmingham, Birmingham, UK
BJU Int 105:784-8. 2010..This might represent a model for the future investigation of urological and other malignancies...- A compendium of familial relative risks of cancer among first degree relatives: a population-based studyMaurice P Zeegers
Unit of Genetic Epidemiology, Department of Public Health and Epidemiology, School of Medicine, The University of Birmingham, Public Health Building, Edgbaston, Birmingham, United Kingdom
Int J Cancer 123:1664-73. 2008..Familial clustering of cancer occurs at most sites but is generally modest. Some observed discordant familial clustering is surprising but should be interpreted with caution as their prior probability is low... - Nitrate intake does not influence bladder cancer risk: the Netherlands cohort studyMaurice P Zeegers
Department of Public Health and Epidemiology, University of Birmingham, Birmingham, United Kingdom
Environ Health Perspect 114:1527-31. 2006..However, the association between nitrate exposure from food or drinking water and bladder cancer has not been substantially investigated in epidemiologic studies... - Physical activity and the risk of prostate cancer in the Netherlands cohort study, results after 9.3 years of follow-upMaurice P A Zeegers
Department of Epidemiology, Maastricht University, Netherlands
Cancer Epidemiol Biomarkers Prev 14:1490-5. 2005..The aim of the current study was to evaluate the relation between physical activity and prostate cancer risk with specific emphasis on interaction with body mass index (BMI) and baseline energy intake... - How strong is the association between CAG and GGN repeat length polymorphisms in the androgen receptor gene and prostate cancer risk?Maurice P Zeegers
Department of Public Health and Epidemiology, School of Medicine, Public Health Building, University of Birmingham, Birmingham B15 2TT, United Kingdom
Cancer Epidemiol Biomarkers Prev 13:1765-71. 2004..The purpose of this meta-analysis was to provide relative and absolute quantitative summary estimates with sufficient power... - Toenail selenium levels and the subsequent risk of prostate cancer: a prospective cohort studyPiet A van den Brandt
Department of Epidemiology, Maastricht University, 6200 MD Maastricht, The Netherlands
Cancer Epidemiol Biomarkers Prev 12:866-71. 2003..These results confirm the hypothesis that higher selenium intake may reduce prostate cancer risk. Future research on optimum dose level is needed... - A prospective study of occupation and prostate cancer riskMaurice P A Zeegers
Department of Epidemiology, Maastricht University, Maastricht, The Netherlands
J Occup Environ Med 46:271-9. 2004..The results for policemen were substantial and statistically significant, although a conservative value for significance level was used... - Alcohol and ovarian cancer risk: results from the Netherlands Cohort StudyLeo J Schouten
Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
Cancer Causes Control 15:201-9. 2004..To study alcohol consumption in relation to ovarian cancer risk in a prospective cohort study... - The effect of smoking on the male excess of bladder cancer: a meta-analysis and geographical analysesMarjolein Hemelt
Unit of Genetic Epidemiology, Department of Public Health and Epidemiology, University of Birmingham, Birmingham, United Kingdom
Int J Cancer 124:412-9. 2009..This implied that, at least in the Western world, smoking can only partially explain the difference in bladder cancer incidence. Consequently, other factors are responsible for the difference in bladder cancer incidence... - The association between smoking, beverage consumption, diet and bladder cancer: a systematic literature reviewMaurice P A Zeegers
Department of Epidemiology, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
World J Urol 21:392-401. 2004..Folate is possibly not associated with bladder cancer. There probably is a moderate inverse association between selenium intake and bladder cancer risk... - The contribution of risk factors to blood pressure heritability estimates in young adults: the East flanders prospective twin studyMaurice P A Zeegers
Maastricht University, Department of Epidemiology, Maastricht, The Netherlands
Twin Res 7:245-53. 2004..The heritability of blood pressure is relatively high in young adults. Potential risk factors of blood pressure do not appear to confound the heritability estimates. However, gene by sex by smoking interaction is indicated... - Health-status of adult survivors of childhood cancer: a large-scale population-based study from the British Childhood Cancer Survivor StudyRaoul C Reulen
Department of Public Health and Epidemiology, Centre for Childhood Cancer Survivor Studies, University of Birmingham, Birmingham, United Kingdom
Int J Cancer 121:633-40. 2007..Although self-reported physical health is at least as good as in the general population among young survivors, this study suggests that perceived physical health declines more rapidly over time than in the general population... - Pregnancy outcomes among adult survivors of childhood cancer in the British Childhood Cancer Survivor StudyRaoul C Reulen
Centre for Childhood Cancer Survivor Studies, Department of Public Health, Epidemiology and Biostatistics, School of Population and Health Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
Cancer Epidemiol Biomarkers Prev 18:2239-47. 2009.... - Mechanisms of recurrence of Ta/T1 bladder cancerRichard T Bryan
Department of Public Health, Epidemiology and Biostatistics, School of Population Sciences, University of Birmingham, Birmingham, UK
Ann R Coll Surg Engl 92:519-24. 2010..However, the relative importance and timing of these mechanisms is currently unknown. Our objective was to postulate the incidence and timing of these mechanisms by investigating the location of bladder cancer recurrences over time... - Prediagnostic toenail selenium and risk of bladder cancerMaurice P A Zeegers
Department of Epidemiology, Maastricht University, The Netherlands
Cancer Epidemiol Biomarkers Prev 11:1292-7. 2002..We conclude that the evidence is in favor of an inverse association between selenium and bladder cancer risk... - Empiric risk of prostate carcinoma for relatives of patients with prostate carcinoma: a meta-analysisMaurice P A Zeegers
Department of Epidemiology, Maastricht University, Maastricht, The Netherlands
Cancer 97:1894-903. 2003.... - Energy restriction and the risk of spontaneous mammary tumors in mice: a meta-analysisMiranda J M Dirx
Maastricht University, Department of Epidemiology, Maastricht, The Netherlands
Int J Cancer 106:766-70. 2003..This meta-analysis confirms that energy restriction in itself consistently protects against the development of mammary tumor in mice, irrespective of the type of restricted nutrient or other study characteristics... - Founder mutations among the DutchMaurice P A Zeegers
Department of Epidemiology, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands
Eur J Hum Genet 12:591-600. 2004..These observations demonstrate the opportunity for gene discovery for other diseases and traits in the Netherlands... - A meta-analysis of observational studies identifies predictors of sickness absenceSaskia F A Duijts
Department of Epidemiology, Maastricht University, 6200 MD, Maastricht, The Netherlands
J Clin Epidemiol 60:1105-15. 2007..To implement preventive measures, it is necessary to identify predictors for this type of sickness absence... - The Birmingham Registry for Twin and Heritability Studies (BiRTHS)Ruth E Krone
Unit of Genetic Epidemiology, Department of Public Health and Epidemiology, University of Birmingham, Birmingham, UK
Twin Res Hum Genet 9:907-12. 2006..The prospective study design gives us the opportunity to obtain data on maternal nutrition (reflected by body mass index) and ante- and postnatal growth and development of twins... - Analysis of germline variants in CDH1, IGFBP3, MMP1, MMP3, STK15 and VEGF in familial and sporadic renal cell carcinomaChristopher Ricketts
Cancer Research UK Renal Molecular Oncology Group, Department of Medical and Molecular Genetics, University of Birmingham School of Medicine, Edgbaston, Birmingham, UK
PLoS ONE 4:e6037. 2009..Hence we hypothesised that low-penetrance functional genetic variants in pathways related to the VHL protein (pVHL) function might (a) modify the phenotypic expression of VHL disease and/or (b) predispose to sporadic RCC... - Cigarette smoking and colorectal cancer: APC mutations, hMLH1 expression, and GSTM1 and GSTT1 polymorphismsMargreet Lüchtenborg
Nutrition and Toxicology Research Institute Maastricht, Department of Epidemiology, Universiteit Maastricht, 6200 MD Maastricht, The Netherlands
Am J Epidemiol 161:806-15. 2005..These results indicate that cigarette smoking is associated with risk of colorectal cancer, and this association may depend on molecular characteristics of the tumor as defined by APC mutation and hMLH1 expression status... - Genetic risk of atherosclerotic renal artery disease: the candidate gene approach in a renal angiography cohortMarieke van Onna
Department of Internal Medicine, University Hospital Maastrichtand Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands
Hypertension 44:448-53. 2004..We hypothesize that the Asp allele of the Glu298Asp polymorphism may predispose to the development of atherosclerotic lesions but that renal artery involvement depends on other factors, also... - A prospective study on active and environmental tobacco smoking and bladder cancer risk (The Netherlands)Maurice P A Zeegers
Department of Epidemiology, Maastricht, The Netherlands
Cancer Causes Control 13:83-90. 2002..In a prospective cohort study among 120,852 adult subjects the authors investigated the associations between cigarette, cigar, pipe, environmental tobacco smoking (ETS), and bladder cancer...