J Duncan Young

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Modifiable factors influencing relatives' decision to offer organ donation: systematic review
    Arabella L Simpkin
    Intensive Care Society Clinical Trials Group, Kadoorie Centre, John Radcliffe Hospital, Headington, Oxford OX3 9DU
    BMJ 338:b991. 2009
  2. doi request reprint Effect of early vs late tracheostomy placement on survival in patients receiving mechanical ventilation: the TracMan randomized trial
    Duncan Young
    Adult Intensive Care Unit, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, England
    JAMA 309:2121-9. 2013
  3. ncbi request reprint High-frequency oscillation for acute respiratory distress syndrome
    Duncan Young
    John Radcliffe Hospital and the University of Oxford, Oxford, United Kingdom
    N Engl J Med 368:806-13. 2013
  4. pmc Beta Agonist Lung Injury TrIal-2 (BALTI-2) trial protocol: a randomised, double-blind, placebo-controlled of intravenous infusion of salbutamol in the acute respiratory distress syndrome
    Gavin D Perkins
    University of Warwick, Warwick Medical School Clinical Trials Unit, Warwick, CV4 7AL, UK
    Trials 12:113. 2011
  5. pmc Bench to bedside: A role for erythropoietin in sepsis
    Andrew P Walden
    Adult Intensive Care Unit, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Crit Care 14:227. 2010
  6. ncbi request reprint The heart and circulation in severe sepsis
    J D Young
    Adult Intensive Care Unit, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
    Br J Anaesth 93:114-20. 2004
  7. ncbi request reprint Clinical trials of monitoring in anaesthesia, critical care and acute ward care: a review
    D Young
    Nuffield Department of Anaesthetics John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
    Br J Anaesth 97:39-45. 2006
  8. ncbi request reprint The use of pre- pro- and synbiotics in adult intensive care unit patients: systematic review
    Peter J Watkinson
    Intensive Care Society Trials Group, Kadoorie Centre, Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
    Clin Nutr 26:182-92. 2007
  9. pmc Study protocol: the Intensive Care Outcome Network ('ICON') study
    John A Griffiths
    ICS Trials Group, Kadoorie Centre, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
    BMC Health Serv Res 8:132. 2008
  10. ncbi request reprint Abnormal cerebral blood volume in regions of contused and normal appearing brain following traumatic brain injury using perfusion magnetic resonance imaging
    M R Garnett
    Department of Biochemistry, University of Oxford, United Kingdom
    J Neurotrauma 18:585-93. 2001

Collaborators

Detail Information

Publications22

  1. pmc Modifiable factors influencing relatives' decision to offer organ donation: systematic review
    Arabella L Simpkin
    Intensive Care Society Clinical Trials Group, Kadoorie Centre, John Radcliffe Hospital, Headington, Oxford OX3 9DU
    BMJ 338:b991. 2009
    ..To identify modifiable factors that influence relatives' decision to allow organ donation...
  2. doi request reprint Effect of early vs late tracheostomy placement on survival in patients receiving mechanical ventilation: the TracMan randomized trial
    Duncan Young
    Adult Intensive Care Unit, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, England
    JAMA 309:2121-9. 2013
    ..Tracheostomy is a widely used intervention in adult critical care units. There is little evidence to guide clinicians regarding the optimal timing for this procedure...
  3. ncbi request reprint High-frequency oscillation for acute respiratory distress syndrome
    Duncan Young
    John Radcliffe Hospital and the University of Oxford, Oxford, United Kingdom
    N Engl J Med 368:806-13. 2013
    ..High-frequency oscillatory ventilation (HFOV) may reduce this secondary damage...
  4. pmc Beta Agonist Lung Injury TrIal-2 (BALTI-2) trial protocol: a randomised, double-blind, placebo-controlled of intravenous infusion of salbutamol in the acute respiratory distress syndrome
    Gavin D Perkins
    University of Warwick, Warwick Medical School Clinical Trials Unit, Warwick, CV4 7AL, UK
    Trials 12:113. 2011
    ....
  5. pmc Bench to bedside: A role for erythropoietin in sepsis
    Andrew P Walden
    Adult Intensive Care Unit, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Crit Care 14:227. 2010
    ..An observational cohort study examining the microvascular effects of erythropoietin is underway and the evidence would support further phase II and III clinical trials examining this molecule as an adjunctive treatment in sepsis...
  6. ncbi request reprint The heart and circulation in severe sepsis
    J D Young
    Adult Intensive Care Unit, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
    Br J Anaesth 93:114-20. 2004
  7. ncbi request reprint Clinical trials of monitoring in anaesthesia, critical care and acute ward care: a review
    D Young
    Nuffield Department of Anaesthetics John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
    Br J Anaesth 97:39-45. 2006
    ..This review highlights some of the studies that have assessed new monitors in anaesthesia, critical care, and other areas of acute care...
  8. ncbi request reprint The use of pre- pro- and synbiotics in adult intensive care unit patients: systematic review
    Peter J Watkinson
    Intensive Care Society Trials Group, Kadoorie Centre, Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
    Clin Nutr 26:182-92. 2007
    ....
  9. pmc Study protocol: the Intensive Care Outcome Network ('ICON') study
    John A Griffiths
    ICS Trials Group, Kadoorie Centre, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
    BMC Health Serv Res 8:132. 2008
    ..The current lack of rigorous longitudinal studies means that the true prevalence of these physical and psychological problems remains undetermined...
  10. ncbi request reprint Abnormal cerebral blood volume in regions of contused and normal appearing brain following traumatic brain injury using perfusion magnetic resonance imaging
    M R Garnett
    Department of Biochemistry, University of Oxford, United Kingdom
    J Neurotrauma 18:585-93. 2001
    ..The current study has shown that regions of both normal appearing and contused brain may have an abnormal rCBV and that alterations in rCBV may play a role in determining the clinical outcome of patients...
  11. ncbi request reprint Altered cellular metabolism following traumatic brain injury: a magnetic resonance spectroscopy study
    M R Garnett
    Department of Biochemistry, University of Oxford, United Kingdom
    J Neurotrauma 18:231-40. 2001
    ....
  12. ncbi request reprint A national survey of intensive care follow-up clinics
    J A Griffiths
    Nuffield Department of Anaesthetics, John Radcliffe Hospital, Oxford, UK
    Anaesthesia 61:950-5. 2006
    ..Nearly half of the follow-up clinics (39 clinics, 49%) have pre-negotiated access to at least one other out-patient service...
  13. ncbi request reprint Integrated monitoring and analysis for early warning of patient deterioration
    L Tarassenko
    Department of Engineering Science, Parks Road, University of Oxford, Oxford OX1 3PJ, UK
    Br J Anaesth 97:64-8. 2006
    ..Retrospective analysis has also shown that the data fusion algorithm in BioSign is capable of detecting critical events in advance of single-channel alerts...
  14. pmc Systematic review and meta-analysis of studies of the timing of tracheostomy in adult patients undergoing artificial ventilation
    John Griffiths
    Adult Intensive Care Unit, John Radcliffe Hospital, Oxford OX3 9DU
    BMJ 330:1243. 2005
    ..To compare outcomes in critically ill patients undergoing artificial ventilation who received a tracheostomy early or late in their treatment...
  15. ncbi request reprint The prevalence of post traumatic stress disorder in survivors of ICU treatment: a systematic review
    John Griffiths
    The John Radcliffe Hospital, Intensive Care Society Trials Group, Kadoorie Centre, Headley Way, OX3 9DU, Headington, Oxford, UK
    Intensive Care Med 33:1506-18. 2007
    ..To determine the prevalence of post traumatic stress disorder in survivors of intensive care treatment...
  16. ncbi request reprint A randomised controlled trial of the effect of continuous electronic physiological monitoring on the adverse event rate in high risk medical and surgical patients
    P J Watkinson
    Intensive Care Society Clinical Trials Group, John Radcliffe Hospital, Oxford, UK
    Anaesthesia 61:1031-9. 2006
    ..We conclude that mandated electronic vital signs monitoring in high risk medical and surgical patients has no effect on adverse events or mortality...
  17. ncbi request reprint Nitric oxide synthase is downregulated, while haem oxygenase is increased, in patients with septic shock
    M C Reade
    Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK
    Br J Anaesth 94:468-73. 2005
    ..Haem oxygenase is upregulated by oxidative stress, but little is known about haem oxygenase expression in human sepsis. Haem oxygenase may modulate nitric oxide production, and may also have a direct effect on vascular tone...
  18. ncbi request reprint Of mice and men (and rats): implications of species and stimulus differences for the interpretation of studies of nitric oxide in sepsis
    M C Reade
    Br J Anaesth 90:115-8. 2003
  19. ncbi request reprint Development and testing of a hierarchical method to code the reason for admission to intensive care units: the ICNARC Coding Method. Intensive Care National Audit & Research Centre
    J D Young
    Nuffield Department of Anaesthetics, Radcliffe Infirmary, Oxford, UK
    Br J Anaesth 87:543-8. 2001
    ..1%) in the primary reason for admission. Five conditions account for 19.4% of all primary reasons for admission. This is the first method to be developed empirically for coding the reason for intensive care admission...
  20. ncbi request reprint "On the subject of multilevel modelling in vascular surgery"
    V G Hadjianastassiou
    Eur J Vasc Endovasc Surg 34:494. 2007
  21. ncbi request reprint New method to evaluate the practice of positive pressure ventilation in intensive care units
    R J Roche
    Nuffield Department of Anaesthetics and Intensive Care Unit, Oxford, UK
    Br J Anaesth 91:419-20. 2003
    ..Many general intensive care units in the UK are being slow to adopt this approach and we therefore set out to devise a method to audit ventilation and possibly influence practice in these units...