Qi Long Ying

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. ncbi request reprint BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    Qi Long Ying
    Institute for Stem Cell Research, University of Edinburgh, King s Buildings, West Mains Road, EH9 3JQ, Edinburgh, Scotland
    Cell 115:281-92. 2003
  2. ncbi request reprint Defined conditions for neural commitment and differentiation
    Qi Long Ying
    Institute for Stem Cell Research, University of Edinburgh, King s Buildings, West Mains Road, Edinburgh, Scotland, EH9 3JQ, UK
    Methods Enzymol 365:327-41. 2003
  3. ncbi request reprint Derivation and propagation of embryonic stem cells in serum- and feeder-free culture
    Jennifer Nichols
    Centre Development in Stem Cell Biology, Institute for Stem Cell Research, University of Edinburgh, Edinburgh, UK
    Methods Mol Biol 329:91-8. 2006
  4. ncbi request reprint Changing potency by spontaneous fusion
    Qi Long Ying
    Centre for Genome Research, University of Edinburgh, The King s Buildings, West Mains Road, Edinburgh EH9 3JQ, UK
    Nature 416:545-8. 2002
  5. pmc Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
    Luciano Conti
    Institute for Stem Cell Research, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Biol 3:e283. 2005
  6. ncbi request reprint Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
    Qi Long Ying
    Institute for Stem Cell Research, University of Edinburgh, King s Buildings, West Mains Road, Edinburgh EH9 3JQ, United Kingdom
    Nat Biotechnol 21:183-6. 2003
  7. ncbi request reprint Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells
    Nathalie Billon
    MRC Laboratory for Molecular Cell Biology and Cell Biology Unit and the Biology Department, University College London, London WC1E 6BT, UK
    J Cell Sci 115:3657-65. 2002

Detail Information

Publications7

  1. ncbi request reprint BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    Qi Long Ying
    Institute for Stem Cell Research, University of Edinburgh, King s Buildings, West Mains Road, EH9 3JQ, Edinburgh, Scotland
    Cell 115:281-92. 2003
    ..Upon LIF withdrawal, Id-expressing ES cells differentiate but do not give rise to neural lineages. We conclude that blockade of lineage-specific transcription factors by Id proteins enables the self-renewal response to LIF/STAT3...
  2. ncbi request reprint Defined conditions for neural commitment and differentiation
    Qi Long Ying
    Institute for Stem Cell Research, University of Edinburgh, King s Buildings, West Mains Road, Edinburgh, Scotland, EH9 3JQ, UK
    Methods Enzymol 365:327-41. 2003
    ....
  3. ncbi request reprint Derivation and propagation of embryonic stem cells in serum- and feeder-free culture
    Jennifer Nichols
    Centre Development in Stem Cell Biology, Institute for Stem Cell Research, University of Edinburgh, Edinburgh, UK
    Methods Mol Biol 329:91-8. 2006
    ..This chapter describes a simple protocol for efficient derivation and maintenance of ES cells from embryos of the 129 and C57B1/6 strains of mice...
  4. ncbi request reprint Changing potency by spontaneous fusion
    Qi Long Ying
    Centre for Genome Research, University of Edinburgh, The King s Buildings, West Mains Road, Edinburgh EH9 3JQ, UK
    Nature 416:545-8. 2002
    ..We propose that transdetermination consequent to cell fusion 10 could underlie many observations otherwise attributed to an intrinsic plasticity of tissue stem cells 9...
  5. pmc Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
    Luciano Conti
    Institute for Stem Cell Research, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Biol 3:e283. 2005
    ..These homogenous cultures will enable delineation of molecular mechanisms that define a tissue-specific stem cell and allow direct comparison with pluripotent ES cells...
  6. ncbi request reprint Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
    Qi Long Ying
    Institute for Stem Cell Research, University of Edinburgh, King s Buildings, West Mains Road, Edinburgh EH9 3JQ, United Kingdom
    Nat Biotechnol 21:183-6. 2003
    ..This system provides a platform for defining the molecular machinery of neural commitment and optimizing the efficiency of neuronal and glial cell production from pluripotent mammalian stem cells...
  7. ncbi request reprint Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells
    Nathalie Billon
    MRC Laboratory for Molecular Cell Biology and Cell Biology Unit and the Biology Department, University College London, London WC1E 6BT, UK
    J Cell Sci 115:3657-65. 2002
    ..This strategy may also be useful for producing human cells for therapy and drug screening...