Zheng Ye

Summary

Affiliation: University of Wales
Country: UK

Publications

  1. ncbi The CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis
    Zheng Ye
    Bioinformatics Group, Centre for Molecular Genetics and Toxicology, School of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK
    Mutagenesis 17:119-26. 2002
  2. ncbi The discovery and confirmation of single nucleotide polymorphisms in the human p53R2 gene by EST database analysis
    Zheng Ye
    Centre for Molecular Genetics and Toxicology, School of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK
    Mutagenesis 17:361-4. 2002
  3. ncbi Genetic polymorphisms in the cytochrome P450 1A1, glutathione S-transferase M1 and T1, and susceptibility to colon cancer
    Zheng Ye
    Centre for Molecular Genetics and Toxicology, School of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea, United Kingdom
    Teratog Carcinog Mutagen 22:385-92. 2002
  4. ncbi Identification of polymorphisms in the human Reprimo gene using public EST data
    Zheng Ye
    Center for Molecular Genetics and Toxicology, School of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea, United Kingdom
    Teratog Carcinog Mutagen 22:485-93. 2002
  5. ncbi Meta-analysis of 20 case-control studies on the N-acetyltransferase 2 acetylation status and colorectal cancer risk
    Zheng Ye
    Bioinformatics Group, Centre for Molecular Genetics and Toxicology, School of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea, UK
    Med Sci Monit 8:CR558-65. 2002
  6. ncbi Quantitative assessment of the effect of angiotensinogen gene polymorphisms on the risk of coronary heart disease
    Ming Qing Xu
    Bio X Life Science Research Centre, Shanghai Jiao Tong University, Shanghai, China
    Circulation 116:1356-66. 2007
  7. pmc Five glutathione s-transferase gene variants in 23,452 cases of lung cancer and 30,397 controls: meta-analysis of 130 studies
    Zheng Ye
    Department of Public Health and Primary Care, University of Cambridge, Strangeways Site, Cambridge, United Kingdom
    PLoS Med 3:e91. 2006
  8. ncbi Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls
    Zheng Ye
    Department of Public Health and Primary Care, University of Cambridge, Strangeways Site, Wort s Causeway, Cambridge CB1 8RN, UK
    Lancet 367:651-8. 2006
  9. ncbi Glutathione s-transferase polymorphisms (GSTM1, GSTP1 and GSTT1) and the risk of acute leukaemia: a systematic review and meta-analysis
    Zheng Ye
    Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
    Eur J Cancer 41:980-9. 2005
  10. ncbi A meta-analysis of 20 case-control studies of the glutathione S-transferase M1 (GSTM1) status and colorectal cancer risk
    Zheng Ye
    Data Mining Group, Department of Computing, Imperial College London, UK
    Med Sci Monit 9:SR83-91. 2003

Collaborators

Detail Information

Publications13

  1. ncbi The CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis
    Zheng Ye
    Bioinformatics Group, Centre for Molecular Genetics and Toxicology, School of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK
    Mutagenesis 17:119-26. 2002
    ..The OR for age at menarche (> or = 13) was 0.87 (95% CI 0.62-1.17). Our results suggest that CYP17 MspA1 polymorphism may be at best a weak modifier of breast cancer risk but is not a significant independent risk factor...
  2. ncbi The discovery and confirmation of single nucleotide polymorphisms in the human p53R2 gene by EST database analysis
    Zheng Ye
    Centre for Molecular Genetics and Toxicology, School of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK
    Mutagenesis 17:361-4. 2002
    ..5%) is higher than either rare allele frequency at position 2752 or 2759 (6 and 6%). Our results suggest that the human EST data may serve as a valuable source for the rapid identification of genetic variation...
  3. ncbi Genetic polymorphisms in the cytochrome P450 1A1, glutathione S-transferase M1 and T1, and susceptibility to colon cancer
    Zheng Ye
    Centre for Molecular Genetics and Toxicology, School of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea, United Kingdom
    Teratog Carcinog Mutagen 22:385-92. 2002
    ..distal). This study suggests that the polymorphisms of CYP1A1 MspI, GSTM1, and GSTT1 are not associated with a significant risk of developing colon cancer in a United Kingdom population...
  4. ncbi Identification of polymorphisms in the human Reprimo gene using public EST data
    Zheng Ye
    Center for Molecular Genetics and Toxicology, School of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea, United Kingdom
    Teratog Carcinog Mutagen 22:485-93. 2002
    ..4%) is much higher than rare allele frequency at position 839 (3.7%). Our results suggest that the human EST data may serve as a valuable source for the rapid identification of genetic variation...
  5. ncbi Meta-analysis of 20 case-control studies on the N-acetyltransferase 2 acetylation status and colorectal cancer risk
    Zheng Ye
    Bioinformatics Group, Centre for Molecular Genetics and Toxicology, School of Biological Sciences, University of Wales Swansea, Singleton Park, Swansea, UK
    Med Sci Monit 8:CR558-65. 2002
    ..To clarify the influence of NAT2 rapid acetylation status on colon cancer risk, we have performed a meta-analysis of 20 published case-control studies (4431 cases, 4547 controls)...
  6. ncbi Quantitative assessment of the effect of angiotensinogen gene polymorphisms on the risk of coronary heart disease
    Ming Qing Xu
    Bio X Life Science Research Centre, Shanghai Jiao Tong University, Shanghai, China
    Circulation 116:1356-66. 2007
    ..Many studies have examined the association between polymorphisms in the angiotensinogen gene and risk of coronary heart disease (CHD), but the results have been inconsistent...
  7. pmc Five glutathione s-transferase gene variants in 23,452 cases of lung cancer and 30,397 controls: meta-analysis of 130 studies
    Zheng Ye
    Department of Public Health and Primary Care, University of Cambridge, Strangeways Site, Cambridge, United Kingdom
    PLoS Med 3:e91. 2006
    ..It has been suggested that polymorphisms in the GST genes are risk factors for lung cancer, but a large number of studies have reported apparently conflicting results...
  8. ncbi Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls
    Zheng Ye
    Department of Public Health and Primary Care, University of Cambridge, Strangeways Site, Wort s Causeway, Cambridge CB1 8RN, UK
    Lancet 367:651-8. 2006
    ..We did meta-analyses on seven such haemostatic genetic variants for which the available evidence on each comprises at least 5000 coronary disease cases and at least 5000 controls...
  9. ncbi Glutathione s-transferase polymorphisms (GSTM1, GSTP1 and GSTT1) and the risk of acute leukaemia: a systematic review and meta-analysis
    Zheng Ye
    Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
    Eur J Cancer 41:980-9. 2005
    ..It is conceivable that GSTM1 and GSTT1 null genotypes may thus play a role in leukemogenesis. A review of the 30 case-control studies indicates that greater attention should be paid to the design of future studies...
  10. ncbi A meta-analysis of 20 case-control studies of the glutathione S-transferase M1 (GSTM1) status and colorectal cancer risk
    Zheng Ye
    Data Mining Group, Department of Computing, Imperial College London, UK
    Med Sci Monit 9:SR83-91. 2003
    ..To re-examine this controversy, we have undertaken a meta-analysis investigating the relationship of GSTM1 status and colon cancer risk...
  11. pmc The crystal structure of CREG, a secreted glycoprotein involved in cellular growth and differentiation
    Michael Sacher
    Montreal Proteomics Network, 740 Doctor Penfield, Montreal, QC, Canada H3A 1A4
    Proc Natl Acad Sci U S A 102:18326-31. 2005
    ..These findings indicate that CREG utilizes a known fold for a previously undescribed function [corrected]..
  12. ncbi Association of apolipoprotein E genotypes with lipid levels and coronary risk
    Anna M Bennet
    Department of Public Health and Primary Care, University of Cambridge, Cambridge, England
    JAMA 298:1300-11. 2007
    ..Previous reviews of associations of apolipoprotein E (apoE) genotype and coronary disease have been dominated by smaller studies that are liable to biases...
  13. doi Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk
    Alexander Thompson
    Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge, England CB1 8RN
    JAMA 299:2777-88. 2008
    ..The importance of the cholesteryl ester transfer protein (CETP) pathway in coronary disease is uncertain. Study of CETP genotypes can help better understand the relevance of this pathway to lipid metabolism and disease risk...