I A Yang

Summary

Affiliation: University of Southampton
Country: UK

Publications

  1. ncbi request reprint Mannose-binding lectin gene polymorphism predicts hospital admissions for COPD infections
    I A Yang
    Division of Thoracic Medicine, The Prince Charles Hospital, and Department of Medicine, University of Queensland, Brisbane, Australia
    Genes Immun 4:269-74. 2003
  2. ncbi request reprint TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis
    Ian A Yang
    Human Genetics Division Mailpoint 808, University of Southampton School of Medicine, Tremona Road, Southampton SO16 6YD, UK
    Atherosclerosis 170:187-90. 2003
  3. ncbi request reprint Toll-like receptor 4 polymorphism and severity of atopy in asthmatics
    I A Yang
    Asthma Genetics Laboratory, Division of Human Genetics and Infection, University of Southampton, Southampton, UK
    Genes Immun 5:41-5. 2004
  4. doi request reprint Genetic association study of CYP1A1 polymorphisms identifies risk haplotypes in nonsmall cell lung cancer
    C M Wright
    Dept of Thoracic Medicine, Room 2, Level 1 Clinical Sciences Building, The Prince Charles Hospital, Chermside, QLD, Australia
    Eur Respir J 35:152-9. 2010
  5. ncbi request reprint Genetic association studies of interleukin-13 receptor alpha1 subunit gene polymorphisms in asthma and atopy
    A K Konstantinidis
    Divisions of Human Genetics, School of Medicine, University of Southampton, Southampton, UK
    Eur Respir J 30:40-7. 2007
  6. doi request reprint Genetic susceptibility to the respiratory effects of air pollution
    I A Yang
    Department of Thoracic Medicine, The Prince Charles Hospital, Rode Road, Chermside, Brisbane QLD 4032, Australia
    Thorax 63:555-63. 2008
  7. ncbi request reprint Cytokine gene polymorphisms in idiopathic pulmonary fibrosis
    R L Riha
    Department of Thoracic Medicine, The Prince Charles Hospital, Brisbane, Queensland, Australia
    Intern Med J 34:126-9. 2004
  8. ncbi request reprint Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome
    N J A Child
    Human Genetics Division and Infection, Inflammation and Repair Division, School of Medicine, University of Southampton, Southampton, UK
    Biochem Soc Trans 31:652-3. 2003
  9. ncbi request reprint Genetic susceptibility to the respiratory effects of air pollution
    I A Yang
    Department of Thoracic Medicine, The Prince Charles Hospital, Rode Road, Chermside, Brisbane QLD 4032, Australia
    Postgrad Med J 85:428-36. 2009
  10. doi request reprint Exploratory study of the 'weekend effect' for acute medical admissions to public hospitals in Queensland, Australia
    M S Clarke
    School of Medicine, The University of Queensland, Brisbane, Queensland, Australia
    Intern Med J 40:777-83. 2010

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Mannose-binding lectin gene polymorphism predicts hospital admissions for COPD infections
    I A Yang
    Division of Thoracic Medicine, The Prince Charles Hospital, and Department of Medicine, University of Queensland, Brisbane, Australia
    Genes Immun 4:269-74. 2003
    ..MBL2 genotype should be explored prospectively as a prognostic marker for infection risk in COPD...
  2. ncbi request reprint TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis
    Ian A Yang
    Human Genetics Division Mailpoint 808, University of Southampton School of Medicine, Tremona Road, Southampton SO16 6YD, UK
    Atherosclerosis 170:187-90. 2003
    ..We analyzed this polymorphism in relation to susceptibility to and severity of coronary artery disease...
  3. ncbi request reprint Toll-like receptor 4 polymorphism and severity of atopy in asthmatics
    I A Yang
    Asthma Genetics Laboratory, Division of Human Genetics and Infection, University of Southampton, Southampton, UK
    Genes Immun 5:41-5. 2004
    ..05). This study confirms the previously observed lack of association of TLR4 polymorphisms with asthma. In contrast, the findings suggest that genetically determined hyporesponsiveness to endotoxin may increase atopy severity...
  4. doi request reprint Genetic association study of CYP1A1 polymorphisms identifies risk haplotypes in nonsmall cell lung cancer
    C M Wright
    Dept of Thoracic Medicine, Room 2, Level 1 Clinical Sciences Building, The Prince Charles Hospital, Chermside, QLD, Australia
    Eur Respir J 35:152-9. 2010
    ..The present study has identified risk haplotypes for CYP1A1 in NSCLC and confirmed that CYP1A1 polymorphisms are a minor risk factor for NSCLC...
  5. ncbi request reprint Genetic association studies of interleukin-13 receptor alpha1 subunit gene polymorphisms in asthma and atopy
    A K Konstantinidis
    Divisions of Human Genetics, School of Medicine, University of Southampton, Southampton, UK
    Eur Respir J 30:40-7. 2007
    ....
  6. doi request reprint Genetic susceptibility to the respiratory effects of air pollution
    I A Yang
    Department of Thoracic Medicine, The Prince Charles Hospital, Rode Road, Chermside, Brisbane QLD 4032, Australia
    Thorax 63:555-63. 2008
    ....
  7. ncbi request reprint Cytokine gene polymorphisms in idiopathic pulmonary fibrosis
    R L Riha
    Department of Thoracic Medicine, The Prince Charles Hospital, Brisbane, Queensland, Australia
    Intern Med J 34:126-9. 2004
    ..Further research is needed to assess the utility of cytokine gene polymorphisms as markers of disease -susceptibility...
  8. ncbi request reprint Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome
    N J A Child
    Human Genetics Division and Infection, Inflammation and Repair Division, School of Medicine, University of Southampton, Southampton, UK
    Biochem Soc Trans 31:652-3. 2003
    ..A trend was found between the minor allele and mortality in SIRS (odds ratio of 4.3; P =0.076), suggesting a role for TLR4 signalling in the severity of SIRS...
  9. ncbi request reprint Genetic susceptibility to the respiratory effects of air pollution
    I A Yang
    Department of Thoracic Medicine, The Prince Charles Hospital, Rode Road, Chermside, Brisbane QLD 4032, Australia
    Postgrad Med J 85:428-36. 2009
    ....
  10. doi request reprint Exploratory study of the 'weekend effect' for acute medical admissions to public hospitals in Queensland, Australia
    M S Clarke
    School of Medicine, The University of Queensland, Brisbane, Queensland, Australia
    Intern Med J 40:777-83. 2010
    ....
  11. ncbi request reprint Cellular localization of interleukin 13 receptor alpha2 in human primary bronchial epithelial cells and fibroblasts
    A K Konstantinidis
    Division of Infection, Inflammation and Repair, School of Medicine, University of Southampton, Southampton, UK
    J Investig Allergol Clin Immunol 18:174-80. 2008
    ..Another IL-13 binding chain, IL-13Ralpha2, binds IL-13 with high affinity but has no known signaling capability and is thought to serve as a decoy receptor providing tight regulation of IL-13 responses...
  12. ncbi request reprint Cochrane systematic reviews of treatments for lung cancer
    K M Fong
    Department of Thoracic Medicine, The Prince Charles Hospital, Brisbane, Australia
    Respir Med 99:1071-8. 2005
    ..The integration of expert clinical experience, patient preference and high-quality evidence, including Cochrane systematic reviews, can only help improve outcomes from this highly lethal condition...
  13. ncbi request reprint Gene expression of lung squamous cell carcinoma reflects mode of lymph node involvement
    J E Larsen
    Dept of Thoracic Medicine, The Prince Charles Hospital, Brisbane, Australia
    Eur Respir J 30:21-5. 2007
    ..This is relevant for prognosis prediction and also for clinical management, particularly in selecting those patients most likely to benefit from adjuvant chemotherapy...
  14. doi request reprint Queensland Lung Cancer Screening Study: rationale, design and methods
    H M Marshall
    Department of Thoracic Medicine, The Prince Charles Hospital, Brisbane, Queensland, Australia
    Intern Med J 43:174-82. 2013
    ..The feasibility of screening in Australia is unknown. This paper describes the rationale, design and methods of the Queensland Lung Cancer Screening Study...
  15. ncbi request reprint The role of Toll-like receptors and related receptors of the innate immune system in asthma
    Ian A Yang
    Department of Thoracic Medicine, The Prince Charles Hospital, Brisbane, Queensland, Australia
    Curr Opin Allergy Clin Immunol 6:23-8. 2006
    ..This review summarizes recent studies of the role of innate immunity receptors, including Toll-like receptors and CD14, in the pathogenesis of asthma...
  16. ncbi request reprint Variation in the toll-like receptor 4 gene and susceptibility to myocardial infarction
    John W Holloway
    Human Genetics Division, School of Medicine, University of Southampton, Southampton, UK
    Pharmacogenet Genomics 15:15-21. 2005
    ....
  17. doi request reprint Interpatient variability in rates of asthma progression: can genetics provide an answer?
    John W Holloway
    Division of Infection, Inflammation and Repair, School of Medicine, University of Southampton, Southampton, United Kingdom
    J Allergy Clin Immunol 121:573-9. 2008
    ....
  18. ncbi request reprint Beta2-Adrenergic receptor polymorphism and asthma: true or false?
    John W Holloway
    Division of Infection, Inflammation and Repair, University of Southhampton, UK
    J Allergy Clin Immunol 115:960-2. 2005
  19. ncbi request reprint Association of tumor necrosis factor-alpha polymorphisms and ozone-induced change in lung function
    Ian A Yang
    Asthma Genetics Laboratory, Human Genetics Division, University of Southampton, United Kingdom
    Am J Respir Crit Care Med 171:171-6. 2005
    ..The results of this study support TNF as a genetic factor for susceptibility to ozone-induced changes in lung function in humans, and has potential implications for stratifying health risks of air pollution...
  20. ncbi request reprint Mucociliary clearance in patients with chronic asthma: effects of beta agonists
    Evangelia Daviskas
    Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    Respirology 10:426-35. 2005
    ..We investigated baseline MCC and the acute effect of terbutaline in chronic asthmatics with sputum production while on long-term treatment with salmeterol in combination with inhaled corticosteroids (ICS)...
  21. ncbi request reprint Association of asthma with a functional promoter polymorphism in the IL16 gene
    Kristin M Burkart
    Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    J Allergy Clin Immunol 117:86-91. 2006
    ..A T-->C single nucleotide polymorphism (SNP) at the -295 position in the promoter region of the IL16 gene has been described...
  22. ncbi request reprint Arg389Gly-beta1-adrenergic receptors determine improvement in left ventricular systolic function in nonischemic cardiomyopathy patients with heart failure after chronic treatment with carvedilol
    Lu Chen
    Department of Medicine, The University of Queensland, Brisbane, Queensland, Australia
    Pharmacogenet Genomics 17:941-9. 2007
    ..We aimed to determine whether these polymorphisms contribute to variability in response to carvedilol in patients with chronic heart failure...
  23. ncbi request reprint Beta2-adrenoceptor polymorphisms and obstructive airway diseases: important issues of study design
    Ian A Yang
    Department of Thoracic Medicine, The Prince Charles Hospital, and School of Medicine, The University of Queensland, Brisbane, Queensland, Australia
    Clin Exp Pharmacol Physiol 34:1029-36. 2007
    ..Enhancing these study design factors will provide high-quality evidence regarding the biological and clinical importance of beta(2)-adrenoceptor pharmacogenomics in asthma and COPD...
  24. ncbi request reprint Gene-environmental interaction in asthma
    Ian A Yang
    Department of Thoracic Medicine, The Prince Charles Hospital, Brisbane, Australia
    Curr Opin Allergy Clin Immunol 7:75-82. 2007
    ..Asthma is likely to result from the effects of environmental stimuli in genetically susceptible individuals. This review summarizes recent studies of gene-environmental interaction in the pathogenesis of asthma, focusing on study designs...