Genomes and Genes
Affiliation: University of Manchester
- Force and the spindle: mechanical cues in mitotic spindle orientationAlexander Nestor-Bergmann
Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom
Semin Cell Dev Biol 34:133-9. 2014....
- Spindle position in symmetric cell divisions during epiboly is controlled by opposing and dynamic apicobasal forcesSarah Woolner
Faculty of Life Sciences, Michael Smith Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
Dev Cell 22:775-87. 2012..We propose that this dynamic mechanism maintains symmetric divisions while allowing the quick adjustment of division plane to facilitate even tissue spreading...
- Unconventional myosins acting unconventionallySarah Woolner
Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester, UK
Trends Cell Biol 19:245-52. 2009..We suggest that the assumption that most unconventional myosins function primarily as organelle transporters might be misguided...
- Myosin-10 and actin filaments are essential for mitotic spindle functionSarah Woolner
Department of Zoology, University of Wisconsin Madison, Madison, WI 53706, USA
J Cell Biol 182:77-88. 2008....
- Imaging the cytoskeleton in live Xenopus laevis embryosSarah Woolner
University of Manchester, Manchester, UK
Methods Mol Biol 586:23-39. 2009..Here, we describe an approach to image the cytoskeleton in embryos of the frog, Xenopus laevis, using mRNA to express fluorescently tagged cytoskeletal probes and confocal microscopy to visualize their dynamic behavior...
- ERK and phosphoinositide 3-kinase temporally coordinate different modes of actin-based motility during embryonic wound healingJingjing Li
Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
J Cell Sci 126:5005-17. 2013..These findings reveal a new mechanism for coordinating different modes of actin-based motility in a complex tissue setting, namely embryonic wound healing...
- Morphogenesis: joining the dots to shape an embryoSarah Woolner
Department of Zoology, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
Curr Biol 17:R289-91. 2007..In the study of morphogenesis, how upstream signalling events are intricately linked to downstream cytoskeletal organisation is not entirely understood. Recent work in the Drosophila embryo has begun to shed light on this problem...
- Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesionLaura A Jones
Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, England, UK
J Cell Biol 207:499-516. 2014..This suggests a novel role for the dynein complex, counteracted by Eg5, in the maintenance of centriole cohesion during mitosis...
- Sisyphus, the Drosophila myosin XV homolog, traffics within filopodia transporting key sensory and adhesion cargosRaymond Liu
Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Development 135:53-63. 2008....
- Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryosBrian Stramer
Department of Physiology, School of Medical Sciences, University of Bristol, UK
EMBO Rep 9:465-71. 2008....
- The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closureSarah Woolner
Department of Anatomy, University College London, Gower Street, London WC1E 6BT, United Kingdom
Dev Biol 282:163-73. 2005....
- Expression in Xenopus oocytes shows that WT1 binds transcripts in vivo, with a central role for zinc finger oneMichael Ladomery
MRC Human Genetics Unit, Western General Hospital, Crewe Rd, Edinburgh EH4 2XU, UK
J Cell Sci 116:1539-49. 2003..We suggest that in evolution, WT1 has acquired the ability to interact with transcripts and splice factors because of the modification of zinc finger one and the +KTS alternative splice...
- Wound healing recapitulates morphogenesis in Drosophila embryosWilliam Wood
Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK
Nat Cell Biol 4:907-12. 2002..Our data suggest a more complex model for epithelial repair than previously envisaged and highlight remarkable similarities with the well-characterized morphogenetic movement of dorsal closure in Drosophila...
- Dynamic analysis of actin cable function during Drosophila dorsal closureAntonio Jacinto
Department of Anatomy andDevelopmental Biology, University College London, United Kingdom
Curr Biol 12:1245-50. 2002....
- Dynamic analysis of dorsal closure in Drosophila: from genetics to cell biologyAntonio Jacinto
Instituto Gulbenkian de Ciencia, Rua da Quinta Grande, 6, 2780 156, Oeiras, Portugal
Dev Cell 3:9-19. 2002....