Philip G Woodman

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. ncbi request reprint Biogenesis of the sorting endosome: the role of Rab5
    P G Woodman
    School of Biological Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK
    Traffic 1:695-701. 2000
  2. ncbi request reprint p97, a protein coping with multiple identities
    Philip G Woodman
    School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    J Cell Sci 116:4283-90. 2003
  3. ncbi request reprint Dynein is required for receptor sorting and the morphogenesis of early endosomes
    Owen J Driskell
    Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Nat Cell Biol 9:113-20. 2007
  4. ncbi request reprint Caspase-mediated cleavage of syntaxin 5 and giantin accompanies inhibition of secretory traffic during apoptosis
    Martin Lowe
    School of Biological Sciences, University of Manchester, 2 205 Stopford Building, Oxford Road, Manchester, M13 9PT, UK
    J Cell Sci 117:1139-50. 2004
  5. doi request reprint Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning
    Connie Lam
    Faculty of Life Sciences, University of Manchester, Manchester, M13 9PT, UK
    J Cell Sci 123:202-12. 2010
  6. pmc Roles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysis
    Neftali Flores-Rodriguez
    Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
    PLoS ONE 6:e24479. 2011
  7. ncbi request reprint Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects
    Aurelie Doyotte
    Faculty of Life Sciences, University of Manchester, Manchester, M13 9PT, UK
    J Cell Sci 118:3003-17. 2005
  8. doi request reprint The first passage probability of intracellular particle trafficking
    Salman S Rogers
    School of Physics and Astronomy, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Phys Chem Chem Phys 12:3753-61. 2010
  9. doi request reprint Modes of correlated angular motion in live cells across three distinct time scales
    Andrew W Harrison
    Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK
    Phys Biol 10:036002. 2013
  10. pmc Multivesicular bodies: co-ordinated progression to maturity
    Philip G Woodman
    Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom
    Curr Opin Cell Biol 20:408-14. 2008

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Biogenesis of the sorting endosome: the role of Rab5
    P G Woodman
    School of Biological Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK
    Traffic 1:695-701. 2000
    ..These advances may be profoundly important in changing the way that we view the sorting endosome and in developing models that properly reflect the dynamic qualities of the endocytic pathway...
  2. ncbi request reprint p97, a protein coping with multiple identities
    Philip G Woodman
    School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    J Cell Sci 116:4283-90. 2003
    ..However, some clues may be found from looking at the role of ubiquitin and the AAA ATPase Vps4 during sorting on the endocytic pathway...
  3. ncbi request reprint Dynein is required for receptor sorting and the morphogenesis of early endosomes
    Owen J Driskell
    Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Nat Cell Biol 9:113-20. 2007
    ..When dynein function is acutely disrupted, efficient recycling of transferrin from EGF-containing endosomes is retarded, loss of Rab5 is slowed and endosome enlargement is reduced...
  4. ncbi request reprint Caspase-mediated cleavage of syntaxin 5 and giantin accompanies inhibition of secretory traffic during apoptosis
    Martin Lowe
    School of Biological Sciences, University of Manchester, 2 205 Stopford Building, Oxford Road, Manchester, M13 9PT, UK
    J Cell Sci 117:1139-50. 2004
    ..The contribution that such an inhibition of trafficking may make towards the generation of an apoptotic phenotype is discussed...
  5. doi request reprint Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning
    Connie Lam
    Faculty of Life Sciences, University of Manchester, Manchester, M13 9PT, UK
    J Cell Sci 123:202-12. 2010
    ..Consistent with this hypothesis, expression of exogenous NDE1 or NDEL1 rescued the effects of LIS1 depletion on Golgi organisation, whereas LIS1 was only partially effective at rescuing the loss of NDE1 and NDEL1...
  6. pmc Roles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysis
    Neftali Flores-Rodriguez
    Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
    PLoS ONE 6:e24479. 2011
    ..Altogether, these findings identify how dynein helps define the dynamics of early endosomes...
  7. ncbi request reprint Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects
    Aurelie Doyotte
    Faculty of Life Sciences, University of Manchester, Manchester, M13 9PT, UK
    J Cell Sci 118:3003-17. 2005
    ..The cisternae are interleaved by a fine matrix but lack other surface elaborations, most notably clathrin...
  8. doi request reprint The first passage probability of intracellular particle trafficking
    Salman S Rogers
    School of Physics and Astronomy, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Phys Chem Chem Phys 12:3753-61. 2010
    ..We show the FPP can quantify complicated movement which is neither completely random nor completely deterministic, making it highly applicable to trafficked particles in cell biology...
  9. doi request reprint Modes of correlated angular motion in live cells across three distinct time scales
    Andrew W Harrison
    Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK
    Phys Biol 10:036002. 2013
    ..Correct analysis of the angular correlations of the detector noise is found to be crucial in modelling the observed phenomena...
  10. pmc Multivesicular bodies: co-ordinated progression to maturity
    Philip G Woodman
    Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom
    Curr Opin Cell Biol 20:408-14. 2008
    ..Cytoskeletal motors, through interactions with these machineries and by regulating MVB movement, help to co-ordinate events leading to a mature, fusion-competent MVB...
  11. pmc Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis
    Jon D Lane
    School of Biological Sciences, University of Manchester, Manchester M13 9PT, United Kingdom
    J Cell Biol 156:495-509. 2002
    ..Our results suggest that GRASP65 is an important structural component required for maintenance of Golgi apparatus integrity...
  12. ncbi request reprint Active relocation of chromatin and endoplasmic reticulum into blebs in late apoptotic cells
    Jon D Lane
    University of Bristol, Department of Biochemistry, School of Medicine, University Walk, Bristol, BS8 1TD, UK
    J Cell Sci 118:4059-71. 2005
    ..Formation of endoplasmic reticulum and chromatin-containing blebs requires both actin and microtubules, and is prevented by the caspase-6 inhibitor zVEID.fmk...