Miles Witham

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. ncbi request reprint Effects of an exercise intervention for older heart failure patients on caregiver burden and emotional distress
    Gerard J Molloy
    School of Psychology, University of Aberdeen, Aberdeen, Scotland, UK
    Eur J Cardiovasc Prev Rehabil 13:381-7. 2006
  2. doi request reprint Association of day length and weather conditions with physical activity levels in older community dwelling people
    Miles D Witham
    Ageing and Health, University of Dundee, Dundee, Scotland
    PLoS ONE 9:e85331. 2014
  3. ncbi request reprint Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomized, controlled trial
    Miles D Witham
    Ageing and Health, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, United Kingdom
    Hypertension 63:706-12. 2014
  4. ncbi request reprint Effect of short-term vitamin D supplementation on markers of vascular health in South Asian women living in the UK--a randomised controlled trial
    Miles D Witham
    Ageing and Health, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, UK Electronic address
    Atherosclerosis 230:293-9. 2013
  5. doi request reprint Effects of vitamin D supplementation on markers of vascular function after myocardial infarction--a randomised controlled trial
    Miles D Witham
    Ageing and Health, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, United Kingdom
    Int J Cardiol 167:745-9. 2013
  6. doi request reprint The effect of vitamin D replacement on markers of vascular health in stroke patients - a randomised controlled trial
    M D Witham
    Ageing and Health, Centre for Cardiovascular and Lung Biology, Division of Medicine, University of Dundee, Dundee DD1 9SY, UK
    Nutr Metab Cardiovasc Dis 22:864-70. 2012
  7. doi request reprint A comparison of the Endurance Shuttle Walk test and the Six Minute Walk test for assessment of exercise capacity in older people
    Miles D Witham
    Ageing and Health, Division of Medical Sciences, University of Dundee, Mailbox 1, Ninewells Hospital, Dundee DD1 9SY, UK
    Aging Clin Exp Res 24:176-80. 2012
  8. doi request reprint Efficacy and cost of an exercise program for functionally impaired older patients with heart failure: a randomized controlled trial
    Miles D Witham
    Ageing and Health and Department of Clinical Pharmacology, Centre for Cardiovascular and Lung Biology, Division of Medical Sciences, University of Dundee, Dundee, UK
    Circ Heart Fail 5:209-16. 2012
  9. pmc Do the malnutrition universal screening tool (MUST) and Birmingham nutrition risk (BNR) score predict mortality in older hospitalised patients?
    Sarah Henderson
    Section of Ageing and Health, University of Dundee, Ninewells Hospital, Dundee, UK
    BMC Geriatr 8:26. 2008
  10. ncbi request reprint Using an individualised quality of life measure in older heart failure patients
    Miles D Witham
    Section of Ageing and Health, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, United Kingdom
    Int J Cardiol 116:40-5. 2007

Detail Information

Publications47

  1. ncbi request reprint Effects of an exercise intervention for older heart failure patients on caregiver burden and emotional distress
    Gerard J Molloy
    School of Psychology, University of Aberdeen, Aberdeen, Scotland, UK
    Eur J Cardiovasc Prev Rehabil 13:381-7. 2006
    ..The impact of exercise programmes for heart failure on those close to the patient is largely unknown. We examined the effect of a hospital and home-based exercise intervention on burden, anxiety and depression of informal caregivers...
  2. doi request reprint Association of day length and weather conditions with physical activity levels in older community dwelling people
    Miles D Witham
    Ageing and Health, University of Dundee, Dundee, Scotland
    PLoS ONE 9:e85331. 2014
    ..We therefore examined the relationship between weather and physical activity in a cohort of older community-dwelling people...
  3. ncbi request reprint Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomized, controlled trial
    Miles D Witham
    Ageing and Health, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, United Kingdom
    Hypertension 63:706-12. 2014
    ..04). There was no significant change in cholesterol or glucose levels. Thus, 6 months of intermittent, high-dose oral vitamin D3 did not reduce blood pressure or left ventricular mass in patients with resistant hypertension. ..
  4. ncbi request reprint Effect of short-term vitamin D supplementation on markers of vascular health in South Asian women living in the UK--a randomised controlled trial
    Miles D Witham
    Ageing and Health, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, UK Electronic address
    Atherosclerosis 230:293-9. 2013
    ..This trial evaluated whether vitamin D supplementation could improve markers of vascular health in South Asian women with low 25-hydroxyvitamin D levels...
  5. doi request reprint Effects of vitamin D supplementation on markers of vascular function after myocardial infarction--a randomised controlled trial
    Miles D Witham
    Ageing and Health, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, United Kingdom
    Int J Cardiol 167:745-9. 2013
    ..We tested whether vitamin D supplementation could improve endothelial function and other markers of vascular function in patients with a history of myocardial infarction...
  6. doi request reprint The effect of vitamin D replacement on markers of vascular health in stroke patients - a randomised controlled trial
    M D Witham
    Ageing and Health, Centre for Cardiovascular and Lung Biology, Division of Medicine, University of Dundee, Dundee DD1 9SY, UK
    Nutr Metab Cardiovasc Dis 22:864-70. 2012
    ..We tested whether vitamin D supplementation could reduce blood pressure and improve markers of vascular health in patients who had previously suffered a stroke...
  7. doi request reprint A comparison of the Endurance Shuttle Walk test and the Six Minute Walk test for assessment of exercise capacity in older people
    Miles D Witham
    Ageing and Health, Division of Medical Sciences, University of Dundee, Mailbox 1, Ninewells Hospital, Dundee DD1 9SY, UK
    Aging Clin Exp Res 24:176-80. 2012
    ..We aimed to compare the reliability, responsiveness and completion rates of the six minute walk with a new test of aerobic exercise capacity - the endurance shuttle walk test...
  8. doi request reprint Efficacy and cost of an exercise program for functionally impaired older patients with heart failure: a randomized controlled trial
    Miles D Witham
    Ageing and Health and Department of Clinical Pharmacology, Centre for Cardiovascular and Lung Biology, Division of Medical Sciences, University of Dundee, Dundee, UK
    Circ Heart Fail 5:209-16. 2012
    ..We tested whether an exercise program tailored to the needs of these patients could improve exercise capacity and quality of life or reduce costs to the National Health Service...
  9. pmc Do the malnutrition universal screening tool (MUST) and Birmingham nutrition risk (BNR) score predict mortality in older hospitalised patients?
    Sarah Henderson
    Section of Ageing and Health, University of Dundee, Ninewells Hospital, Dundee, UK
    BMC Geriatr 8:26. 2008
    ..It is unclear whether screening tools such as the Birmingham Nutrition Risk (BNR) score and the Malnutrition Universal Screening Tool (MUST) can successfully predict outcome in this patient group...
  10. ncbi request reprint Using an individualised quality of life measure in older heart failure patients
    Miles D Witham
    Section of Ageing and Health, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, United Kingdom
    Int J Cardiol 116:40-5. 2007
    ..The Patient Generated Index is a recently introduced tool that allows individualised assessment of quality of life...
  11. ncbi request reprint Long-term follow-up of very old heart failure patients enrolled in a trial of exercise training
    Miles D Witham
    Section of Ageing and Health, University of Dundee, Ninewells Hospital, UK
    Am J Geriatr Cardiol 16:243-8. 2007
    ..6 m/month in nonattenders; P=.03). Similar results were seen for other outcomes. Only a small proportion of the variance in change of any of the outcomes was explained by differences in baseline variables...
  12. doi request reprint The effect of different doses of vitamin D(3) on markers of vascular health in patients with type 2 diabetes: a randomised controlled trial
    M D Witham
    Ageing and Health, Ninewells Hospital, Dundee DD1 9SY, UK
    Diabetologia 53:2112-9. 2010
    ..We compared the effect of 100,000 and 200,000 IU doses of vitamin D(3) on endothelial function, blood pressure and markers of glycaemic control in patients with type 2 diabetes...
  13. doi request reprint The effects of vitamin D supplementation on physical function and quality of life in older patients with heart failure: a randomized controlled trial
    Miles D Witham
    Section of Ageing and Health and Department of Clinical Pharmacology, Division of Medicine, Centre for Cardiovascular and Lung Biology, University of Dundee, Ninewells Hospital, Dundee, United Kingdom
    Circ Heart Fail 3:195-201. 2010
    ..We tested whether vitamin D supplementation of patients with heart failure and vitamin D insufficiency can improve physical function and quality of life...
  14. doi request reprint Interventions to achieve long-term weight loss in obese older people: a systematic review and meta-analysis
    Miles D Witham
    Section of Ageing and Health, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, UK
    Age Ageing 39:176-84. 2010
    ..the prevalence of obesity is rapidly increasing in older adults. Information is required about what interventions are effective in reducing obesity and influencing health outcomes in this age group...
  15. doi request reprint Pilot study of an exercise intervention suitable for older heart failure patients with left ventricular systolic dysfunction
    Miles D Witham
    Section of Ageing and Health, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, United Kingdom
    Eur J Cardiovasc Nurs 7:303-6. 2008
    ..Most studies of exercise training for heart failure have been conducted on relatively young patients with little comorbidity. Such programmes are unsuitable for the majority of older frail heart failure patients...
  16. pmc Validation of an individualised quality of life measure in older day hospital patients
    Miles D Witham
    Section of Ageing and Health, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, UK
    Health Qual Life Outcomes 6:27. 2008
    ..To test the ease of use, reliability, responsiveness and construct validity of the Patient Generated Index, an individualised quality of life score, in older people attending a Medicine for Older People Day Hospital...
  17. doi request reprint Effect of vitamin D on blood pressure: a systematic review and meta-analysis
    Miles D Witham
    Section of Ageing and Health, Centre for Cardiovascular and Lung Biology, Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland
    J Hypertens 27:1948-54. 2009
    ..Vitamin D insufficiency has been linked to hypertension and cardiovascular events in observational studies. It is unclear whether vitamin D supplementation can reduce blood pressure, and, if so, by how much...
  18. ncbi request reprint B-type natriuretic peptide is associated with mortality in older functionally impaired patients
    Miles D Witham
    Section of Aging and Health, University of Dundee, Ninewells Hospital, Dundee, Scotland
    J Am Geriatr Soc 53:1991-5. 2005
    ..To determine the predictive power of B-type natriuretic peptide (BNP) regarding death in older, functionally impaired patients with multiple comorbidity...
  19. doi request reprint Vitamin D in chronic heart failure
    Miles D Witham
    Section of Ageing and Health, Centre for Cardiovascular and Lung Biology, Division of Medical Sciences, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, Scotland, UK
    Curr Heart Fail Rep 8:123-30. 2011
    ..Further studies are needed to establish whether larger doses of vitamin D given over a longer period of time can reduce symptoms, hospitalization, and mortality in heart failure...
  20. ncbi request reprint Grossly elevated serum angiotensin-converting enzyme activities are still suppressible with ACE inhibitor therapy
    Miles D Witham
    Section of Ageing and Health, Ninewells Hospital, Dundee, Scotland
    J Renin Angiotensin Aldosterone Syst 3:138. 2002
  21. ncbi request reprint Occult transfixation of the sigmoid colon by suprapubic catheter
    Miles D Witham
    Section of Ageing and Health, Ninewells Hospital, Dundee DD1 9SY, UK
    Age Ageing 31:407-8. 2002
    ..One day after the catheter was changed, he passed faeculent material in the catheter and became unwell with abdominal pain. The catheter tip was visible per rectum...
  22. ncbi request reprint Exercise training as a therapy for chronic heart failure: can older people benefit?
    Miles D Witham
    Section of Aging and Health, Department of Clinical Pharmacology, Ninewells Hospital and Medical School, University of Dundee, UnitedKingdom
    J Am Geriatr Soc 51:699-709. 2003
    ..To realize these potential benefits, exercise programs that are suitable for older, frail people need to be established and tested in an older, frail, unselected population with comorbidities...
  23. ncbi request reprint Organising a regional teaching programme for the MRCP (UK) examination
    Miles Witham
    Section of Ageing and Health, Ninewells Hospital and Medical School, Dundee DD1 9SY
    BMJ 327:s172. 2003
  24. ncbi request reprint Hypothetical economic analysis of screening for left ventricular hypertrophy in high-risk normotensive populations
    M D Witham
    Section of Ageing and Health, Ninewells Hospital and Medical School, Dundee, UK
    QJM 97:87-93. 2004
    ..The prevalence of echocardiographic LVH in patients with high cardiovascular risk appears to be high, even in patients currently considered normotensive...
  25. ncbi request reprint Age is not a significant risk factor for failed trial of beta-blocker therapy in older patients with chronic heart failure
    Miles D Witham
    Section of Ageing and Health, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Age Ageing 33:467-72. 2004
    ..To evaluate how well older heart failure patients tolerate beta-blockers in everyday clinical practice...
  26. ncbi request reprint Effect of a seated exercise program to improve physical function and health status in frail patients > or = 70 years of age with heart failure
    Miles D Witham
    Section of Ageing and Health and Department of Clinical Pharmacology, University of Dundee, Ninewells Hospital, Dundee, United Kingdom
    Am J Cardiol 95:1120-4. 2005
    ..Six-minute walk distance and quality of life did not change between groups, but daily activity as measured by accelerometry increased in the exercise group relative to the control group...
  27. doi request reprint Trends in function and postdischarge mortality in a medicine for the elderly rehabilitation center over a 10-year period
    Miles D Witham
    Ageing and Health, University of Dundee, Ninewells Hospital, Dundee, Scotland, UK
    Arch Phys Med Rehabil 92:1288-92. 2011
    ..To ascertain trends in function and mortality after admission to a medicine for the elderly rehabilitation unit, and to analyze factors associated with these outcomes...
  28. ncbi request reprint Predictors of exercise capacity and everyday activity in older heart failure patients
    Miles D Witham
    Section of Ageing and Health, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, UK
    Eur J Heart Fail 8:203-7. 2006
    ..Exercise capacity and daily activity are key outcomes for older, frail heart failure patients. Little is known about the determinants of these outcomes in this patient group...
  29. pmc Tolerability of spironolactone in patients with chronic heart failure -- a cautionary message
    Miles D Witham
    Section of Ageing and Health, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Br J Clin Pharmacol 58:554-7. 2004
    ..To assess how well heart failure patients tolerate spironolactone in routine clinical practice...
  30. pmc Effect of perindopril on physical function in elderly people with functional impairment: a randomized controlled trial
    Deepa Sumukadas
    Section of Ageing and Health, University of Dundee, Dundee, UK
    CMAJ 177:867-74. 2007
    ..We sought to examine the effect of the angiotensin-converting-enzyme (ACE) inhibitor perindopril on physical function in elderly people with functional impairment who had no heart failure or left ventricular systolic dysfunction...
  31. ncbi request reprint Do ACE inhibitors improve the response to exercise training in functionally impaired older adults? A randomized controlled trial
    Deepa Sumukadas
    Division of Cardiovascular and Diabetes Medicine, University of Dundee, UK
    J Gerontol A Biol Sci Med Sci 69:736-43. 2014
    ..It is unclear whether ACEi provide additional benefit when added to a standard exercise training program. We examined the effects of ACEi therapy on physical function in older people undergoing exercise training...
  32. ncbi request reprint Defining the nutritional status and dietary intake of older heart failure patients
    Rosemary J G Price
    Section of Ageing and Health, Division of Medicine and Therapeutics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    Eur J Cardiovasc Nurs 6:178-83. 2007
    ..Little information exists about diet in the management of heart failure...
  33. ncbi request reprint Autonomic effects of spironolactone and MR blockers in heart failure
    Justine I Davies
    Department of Clinical Pharmacology, Division of Medicine, Dundee, Scotland, DD1 9SY
    Heart Fail Rev 10:63-9. 2005
    ..We conclude that neurohormonal dysfunction is an important component of chronic heart failure, which is affected by aldosterone and can be modified by the use of aldosterone receptor blockade...
  34. ncbi request reprint Using the RT3 accelerometer to measure everyday activity in functionally impaired older people
    Deepa Sumukadas
    Section of Ageing and Health, Department of Medicine and Therapeutics, University of Dundee, Dundee, UK
    Aging Clin Exp Res 20:15-8. 2008
    ..This study aimed to examine the effect of accelerometer placement, use of walking aids, and different types of physical activity on Stay- Healthy RT3 triaxial accelerometer readings in older people...
  35. ncbi request reprint Change in the use of renin-angiotensin system blockers in older patients fulfilling the HOPE criteria
    Deepa Sumukadas
    University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
    J Renin Angiotensin Aldosterone Syst 6:161-2. 2005
  36. ncbi request reprint Are elderly people with the HOPE criteria prescribed angiotensin-converting enzyme inhibitors?
    Deepa Sumukadas
    Department of Medicine and Therapeutics, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK
    J Renin Angiotensin Aldosterone Syst 5:26. 2004
  37. doi request reprint Vitamin D and cardiovascular prevention
    M Adnan Nadir
    Department of Clinical Pharmacology, Centre for Cardiovascular and Lung Biology, Division of Medicine, University of Dundee, Ninewells Hospital, Dundee, UK
    Cardiovasc Ther 28:e5-12. 2010
    ..This article reviews the physiology and function of vitamin D, examines the current observational and intervention data in cardiovascular disease, and discusses future research and current practice recommendations...
  38. ncbi request reprint Changes in serum magnesium and phosphate in older hospitalised patients--correlation with muscle strength and risk factors for refeeding syndrome
    S Henderson
    Department of Medicine for the Elderly, Royal Victoria Hospital, Edinburgh, UK
    J Nutr Health Aging 14:872-6. 2010
    ....
  39. pmc Health and welfare of older people in care homes
    Marion E T McMurdo
    BMJ 334:913-4. 2007
  40. ncbi request reprint Don't shoot the messenger: the 6-minute walk test is a useful outcome measure in exercise trials
    Miles D Witham
    Am Heart J 146:E7. 2003
  41. ncbi request reprint Hyperkalemia after the publication of RALES
    Miles D Witham
    N Engl J Med 351:2448-50; author reply 2448-50. 2004
  42. ncbi request reprint Pragmatic measures of outcome in trials of exercise training
    Miles D Witham
    Age Ageing 32:234-5. 2003
  43. pmc Exercise training and heart failure
    Miles D Witham
    Br J Gen Pract 52:413-4. 2002
  44. ncbi request reprint Family caregiving and congestive heart failure. Review and analysis
    Gerard J Molloy
    School of Psychology, University of St Andrews, St Andrews KY16 9JU, Scotland
    Eur J Heart Fail 7:592-603. 2005
    ..In this paper, we provide a review and analysis of studies that have explicitly investigated these issues in the informal carers of CHF patients...
  45. pmc Including older people in clinical research
    Marion E T McMurdo
    BMJ 331:1036-7. 2005
  46. ncbi request reprint ACE inhibitors for sarcopenia--as good as exercise training?
    Miles D Witham
    Age Ageing 37:363-5. 2008
  47. pmc Vitamin D deficiency: More evidence is needed before general supplementation
    Miles D Witham
    BMJ 336:1451. 2008